Protein O-fucosylation: structure and function
Holdener, Bernadette C, Haltiwanger, Robert S
Published in Current opinion in structural biology (01.06.2019)
Published in Current opinion in structural biology (01.06.2019)
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Journal Article
Significance of glycosylation in Notch signaling
Takeuchi, Hideyuki, Haltiwanger, Robert S.
Published in Biochemical and biophysical research communications (17.10.2014)
Published in Biochemical and biophysical research communications (17.10.2014)
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Journal Article
Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity
Luca, Vincent C., Kim, Byoung Choul, Ge, Chenghao, Kakuda, Shinako, Wu, Di, Roein-Peikar, Mehdi, Haltiwanger, Robert S., Zhu, Cheng, Ha, Taekjip, Garcia, K. Christopher
Published in Science (American Association for the Advancement of Science) (24.03.2017)
Published in Science (American Association for the Advancement of Science) (24.03.2017)
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Journal Article
Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2
Kakuda, Shinako, LoPilato, Rachel K., Ito, Atsuko, Haltiwanger, Robert S.
Published in The Journal of biological chemistry (23.10.2020)
Published in The Journal of biological chemistry (23.10.2020)
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Journal Article
O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking
Takeuchi, Hideyuki, Yu, Hongjun, Hao, Huilin, Takeuchi, Megumi, Ito, Atsuko, Li, Huilin, Haltiwanger, Robert S.
Published in The Journal of biological chemistry (22.09.2017)
Published in The Journal of biological chemistry (22.09.2017)
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Journal Article
Regulation of Notch Function by O-Glycosylation
Harvey, Beth M, Haltiwanger, Robert S
Published in Advances in experimental medicine and biology (01.01.2018)
Published in Advances in experimental medicine and biology (01.01.2018)
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Journal Article
Peters Plus Syndrome Mutations Disrupt a Noncanonical ER Quality-Control Mechanism
Vasudevan, Deepika, Takeuchi, Hideyuki, Johar, Sumreet Singh, Majerus, Elaine, Haltiwanger, Robert S.
Published in Current biology (02.02.2015)
Published in Current biology (02.02.2015)
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Journal Article
Jagged1 heterozygosity in mice results in a congenital cholangiopathy which is reversed by concomitant deletion of one copy of Poglut1 (Rumi)
Thakurdas, Shakeel M., Lopez, Mario F., Kakuda, Shinako, Fernandez‐Valdivia, Rodrigo, Zarrin‐Khameh, Neda, Haltiwanger, Robert S., Jafar‐Nejad, Hamed
Published in Hepatology (Baltimore, Md.) (01.02.2016)
Published in Hepatology (Baltimore, Md.) (01.02.2016)
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Journal Article
Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism
Yu, Hongjun, Takeuchi, Megumi, LeBarron, Jamie, Kantharia, Joshua, London, Erwin, Bakker, Hans, Haltiwanger, Robert S, Li, Huilin, Takeuchi, Hideyuki
Published in Nature chemical biology (01.11.2015)
Published in Nature chemical biology (01.11.2015)
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Journal Article
Fringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligands
Taylor, Paul, Takeuchi, Hideyuki, Sheppard, Devon, Chillakuri, Chandramouli, Lea, Susan M., Haltiwanger, Robert S., Handford, Penny A.
Published in Proceedings of the National Academy of Sciences - PNAS (20.05.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (20.05.2014)
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Journal Article
Inhibition of Delta-induced Notch signaling using fucose analogs
Schneider, Michael, Kumar, Vivek, Nordstrøm, Lars Ulrik, Feng, Lei, Takeuchi, Hideyuki, Hao, Huilin, Luca, Vincent C, Garcia, K Christopher, Stanley, Pamela, Wu, Peng, Haltiwanger, Robert S
Published in Nature chemical biology (01.01.2018)
Published in Nature chemical biology (01.01.2018)
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Journal Article
O-Fucosylation of ADAMTSL2 is required for secretion and is impacted by geleophysic dysplasia-causing mutations
Zhang, Ao, Berardinelli, Steven J., Leonhard-Melief, Christina, Vasudevan, Deepika, Liu, Ta-Wei, Taibi, Andrew, Giannone, Sharee, Apte, Suneel S., Holdener, Bernadette C., Haltiwanger, Robert S.
Published in The Journal of biological chemistry (13.11.2020)
Published in The Journal of biological chemistry (13.11.2020)
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Journal Article
Hydrocephalus in mouse B3glct mutants is likely caused by defects in multiple B3GLCT substrates in ependymal cells and subcommissural organ
Neupane, Sanjiv, Goto, June, Berardinelli, Steven J, Ito, Atsuko, Haltiwanger, Robert S, Holdener, Bernadette C
Published in Glycobiology (Oxford) (09.09.2021)
Published in Glycobiology (Oxford) (09.09.2021)
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