Characterization of residual debris on packaged hip arthroplasty stems demonstrates the dominance of less than 10 μm sized particulate: Updated USP788 guidelines for orthopedic implants
Hallab, Nadim J, Hallab, Salem R, Alexander, Anastasia, Pourzal, Robin
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01.02.2024)
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01.02.2024)
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Cobalt Alloy Implant Debris Induces Inflammation and Bone Loss Primarily through Danger Signaling, Not TLR4 Activation: Implications for DAMP-ening Implant Related Inflammation
Samelko, Lauryn, Landgraeber, Stefan, McAllister, Kyron, Jacobs, Joshua, Hallab, Nadim James
Published in PloS one (28.07.2016)
Published in PloS one (28.07.2016)
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Orthopedic implant cobalt-alloy particles produce greater toxicity and inflammatory cytokines than titanium alloy and zirconium alloy-based particles in vitro, in human osteoblasts, fibroblasts, and macrophages
Dalal, Ali, Pawar, Vivek, McAllister, Kyron, Weaver, Carolyn, Hallab, Nadim J.
Published in Journal of biomedical materials research. Part A (01.08.2012)
Published in Journal of biomedical materials research. Part A (01.08.2012)
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Journal Article
Biologic effects of implant debris
Hallab, Nadim J, Jacobs, Joshua J
Published in Bulletin of the NYU Hospital for Joint Diseases (2009)
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Published in Bulletin of the NYU Hospital for Joint Diseases (2009)
Journal Article
Soluble and particulate Co-Cr-Mo alloy implant metals activate the inflammasome danger signaling pathway in human macrophages: A novel mechanism for implant debris reactivity
Caicedo, Marco S., Desai, Ronak, McAllister, Kyron, Reddy, Anand, Jacobs, Joshua J., Hallab, Nadim J.
Published in Journal of orthopaedic research (01.07.2009)
Published in Journal of orthopaedic research (01.07.2009)
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Journal Article
Increasing both CoCrMo-alloy particle size and surface irregularity induces increased macrophage inflammasome activation in vitro potentially through lysosomal destabilization mechanisms
Caicedo, Marco S., Samelko, Lauryn, McAllister, Kyron, Jacobs, Joshua J., Hallab, Nadim J.
Published in Journal of orthopaedic research (01.10.2013)
Published in Journal of orthopaedic research (01.10.2013)
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Journal Article
Trunnion Corrosion in Total Hip Arthroplasty-Basic Concepts
Urish, Kenneth L, Giori, Nicholas John, Lemons, Jack E, Mihalko, William M, Hallab, Nadim
Published in The Orthopedic clinics of North America (01.07.2019)
Published in The Orthopedic clinics of North America (01.07.2019)
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Sterile particle-induced inflammation is mediated by macrophages releasing IL-33 through a Bruton's tyrosine kinase-dependent pathway
Mishra, Pankaj K, Palma, Mark, Buechel, Bonnie, Moore, Jeffrey, Davra, Viralkumar, Chu, Niansheng, Millman, Ariel, Hallab, Nadim J, Kanneganti, Thirumala-Devi, Birge, Raymond B, Behrens, Edward M, Rivera, Amariliz, Beebe, Kathleen S, Benevenia, Joseph, Gause, William C
Published in Nature materials (01.03.2019)
Published in Nature materials (01.03.2019)
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Journal Article
Do Battlefield Injury-acquired Indwelling Metal Fragments Induce Metal Immunogenicity?
Samelko, Lauryn, Petfield, Joseph, McAllister, Kyron, Hsu, Joseph, Hawkinson, Michael, Jacobs, Joshua J, Hallab, Nadim J
Published in Clinical orthopaedics and related research (01.04.2020)
Published in Clinical orthopaedics and related research (01.04.2020)
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Soluble ions more than particulate cobalt-alloy implant debris induce monocyte costimulatory molecule expression and release of proinflammatory cytokines critical to metal-induced lymphocyte reactivity
Caicedo, Marco S., Pennekamp, Peter H., McAllister, Kyron, Jacobs, Joshua J., Hallab, Nadim J.
Published in Journal of biomedical materials research. Part A (15.06.2010)
Published in Journal of biomedical materials research. Part A (15.06.2010)
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Journal Article
Fretting-corrosion in hip taper modular junctions: The influence of topography and pH levels – An in-vitro study
Royhman, Dmitry, Pourzal, Robin, Hall, Deborah, Lundberg, Hannah J., Wimmer, Markus A., Jacobs, Joshua, Hallab, Nadim J., Mathew, Mathew T.
Published in Journal of the mechanical behavior of biomedical materials (01.06.2021)
Published in Journal of the mechanical behavior of biomedical materials (01.06.2021)
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Females with Unexplained Joint Pain Following Total Joint Arthroplasty Exhibit a Higher Rate and Severity of Hypersensitivity to Implant Metals Compared with Males: Implications of Sex-Based Bioreactivity Differences
Caicedo, Marco S, Solver, Edward, Coleman, Latasha, Jacobs, Joshua J, Hallab, Nadim J
Published in Journal of bone and joint surgery. American volume (19.04.2017)
Published in Journal of bone and joint surgery. American volume (19.04.2017)
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