The Mycobacterium tuberculosis MmpL3 inhibitor MSU-43085 is active in a mouse model of infection
Williams, John T, Giletto, Matthew, Haiderer, Elizabeth R, Aleiwi, Bilal, Krieger-Burke, Teresa, Ellsworth, Edmund, Abramovitch, Robert B
Published in Microbiology spectrum (11.01.2024)
Published in Microbiology spectrum (11.01.2024)
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Identification of New MmpL3 Inhibitors by Untargeted and Targeted Mutant Screens Defines MmpL3 Domains with Differential Resistance
Williams, John T, Haiderer, Elizabeth R, Coulson, Garry B, Conner, Kayla N, Ellsworth, Edmund, Chen, Chao, Alvarez-Cabrera, Nadine, Li, Wei, Jackson, Mary, Dick, Thomas, Abramovitch, Robert B
Published in Antimicrobial agents and chemotherapy (01.10.2019)
Published in Antimicrobial agents and chemotherapy (01.10.2019)
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Discovery and characterization of antimycobacterial nitro-containing compounds with distinct mechanisms of action and in vivo efficacy
Eke, Ifeanyichukwu E., Williams, John T., Haiderer, Elizabeth R., Albrecht, Veronica J., Murdoch, Heather M., Abdalla, Bassel J., Abramovitch, Robert B.
Published in Antimicrobial agents and chemotherapy (19.09.2023)
Published in Antimicrobial agents and chemotherapy (19.09.2023)
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Total synthesis of dissectol A, using an enediolate-based Tsuji-Trost reaction
Andringa, Ruben L. H, Marinus, Nittert, Bunt, Daan V, Haiderer, Elizabeth R, Abramovitch, Robert B, Brown, Christopher D, Rhee, Kyu Y, Witte, Martin D, Minnaard, Adriaan J
Published in Chemical science (Cambridge) (10.07.2024)
Published in Chemical science (Cambridge) (10.07.2024)
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Targeting Mycobacterium tuberculosis Sensitivity to Thiol Stress at Acidic pH Kills the Bacterium and Potentiates Antibiotics
Coulson, Garry B., Johnson, Benjamin K., Zheng, Huiqing, Colvin, Christopher J., Fillinger, Robert J., Haiderer, Elizabeth R., Hammer, Neal D., Abramovitch, Robert B.
Published in Cell chemical biology (17.08.2017)
Published in Cell chemical biology (17.08.2017)
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Acidic pH-dependent depletion of Mycobacterium tuberculosis thiol pools potentiates antibiotics and oxidizing agents
Coulson, Garry B, Johnson, Benjamin K, Colvin, Christopher J, Fillinger, Robert J, Zheng, Huiqing, Haiderer, Elizabeth R, Hammer, Neal D, Abramovitch, Robert B
Published in bioRxiv (21.12.2016)
Published in bioRxiv (21.12.2016)
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