CRISPR/Cas9-mediated ELANE knockout enables neutrophilic maturation of primary hematopoietic stem and progenitor cells and induced pluripotent stem cells of severe congenital neutropenia patients
Nasri, Masoud, Ritter, Malte, Mir, Perihan, Dannenmann, Benjamin, Aghaallaei, Narges, Amend, Diana, Makaryan, Vahagn, Xu, Yun, Fletcher, Breanna, Bernhard, Regine, Steiert, Ingeborg, Hahnel, Karin, Berger, Jürgen, Koch, Iris, Sailer, Brigitte, Hipp, Katharina, Zeidler, Cornelia, Klimiankou, Maksim, Bajoghli, Baubak, Dale, David C, Welte, Karl, Skokowa, Julia
Published in Haematologica (Roma) (01.03.2020)
Published in Haematologica (Roma) (01.03.2020)
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Pretreatment frequency of circulating IL‐17+CD4+ T‐cells, but not Tregs, correlates with clinical response to whole‐cell vaccination in prostate cancer patients
Derhovanessian, Evelyna, Adams, Victoria, Hähnel, Karin, Groeger, Andrea, Pandha, Hardev, Ward, Stephen, Pawelec, Graham
Published in International journal of cancer (15.09.2009)
Published in International journal of cancer (15.09.2009)
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Journal Article
Infection with cytomegalovirus but not herpes simplex virus induces the accumulation of late-differentiated CD4+ and CD8+ T-cells in humans
DERHOVANESSIAN, Evelyna, MAIER, Andrea B, HÄHNEL, Karin, BECK, Robert, DE CRAEN, Anton J. M, SLAGBOOM, Eline P, WESTENDORP, Rudi G. J, PAWELEC, Graham
Published in Journal of general virology (01.12.2011)
Published in Journal of general virology (01.12.2011)
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Journal Article
Hallmark features of immunosenescence are absent in familial longevity
Derhovanessian, Evelyna, Maier, Andrea B, Beck, Robert, Jahn, Gerhard, Hähnel, Karin, Slagboom, P Eline, de Craen, Anton J M, Westendorp, Rudi G J, Pawelec, Graham
Published in The Journal of immunology (1950) (15.10.2010)
Published in The Journal of immunology (1950) (15.10.2010)
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Journal Article
CCR4+ Regulatory T Cells Accumulate in the Very Elderly and Correlate With Superior 8-Year Survival
Derhovanessian, Evelyna, Chen, Sijia, Maier, Andrea B, Hähnel, Karin, de Craen, Anton J M, Roelofs, Helene, Westendorp, Rudi, Pawelec, Graham
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.08.2015)
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.08.2015)
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Journal Article
Impact of Cytomegalovirus Infection and Genetic Background on the Frequencies of Peripheral Blood Suppressor Cells in Human Twins
Goldeck, David, Larsen, Lisbeth Aagaard, Christensen, Kaare, Hamprecht, Klaus, Öttinger, Lilly, Hähnel, Karin, Pawelec, Graham
Published in Pathogens (Basel) (30.07.2021)
Published in Pathogens (Basel) (30.07.2021)
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Journal Article
Lower proportion of naïve peripheral CD8+ T cells and an unopposed pro-inflammatory response to human Cytomegalovirus proteins in vitro are associated with longer survival in very elderly people
Derhovanessian, Evelyna, Maier, Andrea B., Hähnel, Karin, Zelba, Henning, de Craen, Anton J. M., Roelofs, Helene, Slagboom, Eline P., Westendorp, Rudi G. J., Pawelec, Graham
Published in AGE (01.08.2013)
Published in AGE (01.08.2013)
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Journal Article
Genetic Influence on the Peripheral Differentiation Signature of Vδ2+ γδ and CD4+ αβ T Cells in Adults
Beucke, Nicola, Wingerter, Svenja, Hähnel, Karin, Larsen, Lisbeth Aagaard, Christensen, Kaare, Pawelec, Graham, Wistuba-Hamprecht, Kilian
Published in Cells (Basel, Switzerland) (11.02.2021)
Published in Cells (Basel, Switzerland) (11.02.2021)
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Journal Article
Cytomegalovirus-associated accumulation of late-differentiated CD4 T-cells correlates with poor humoral response to influenza vaccination
Derhovanessian, Evelyna, Theeten, Heidi, Hähnel, Karin, Van Damme, Pierre, Cools, Nathalie, Pawelec, Graham
Published in Vaccine (11.01.2013)
Published in Vaccine (11.01.2013)
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Journal Article
Latent infection with cytomegalovirus is associated with poor memory CD4 responses to influenza A core proteins in the elderly
Derhovanessian, Evelyna, Maier, Andrea B, Hähnel, Karin, McElhaney, Janet E, Slagboom, Eline P, Pawelec, Graham
Published in The Journal of immunology (1950) (01.10.2014)
Published in The Journal of immunology (1950) (01.10.2014)
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Journal Article
New insights into the pathomechanism of cyclic neutropenia
Mir, Perihan, Klimiankou, Maksim, Findik, Betuel, Hähnel, Karin, Mellor‐Heineke, Sabine, Zeidler, Cornelia, Skokowa, Julia, Welte, Karl
Published in Annals of the New York Academy of Sciences (01.04.2020)
Published in Annals of the New York Academy of Sciences (01.04.2020)
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Journal Article
Cover Image, Volume 1466, Issue 1
Mir, Perihan, Klimiankou, Maksim, Findik, Betuel, Hähnel, Karin, Mellor‐Heineke, Sabine, Zeidler, Cornelia, Skokowa, Julia, Welte, Karl
Published in Annals of the New York Academy of Sciences (01.04.2020)
Published in Annals of the New York Academy of Sciences (01.04.2020)
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LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis
Morishima, Tatsuya, Krahl, Ann-Christin, Nasri, Masoud, Xu, Yun, Aghaallaei, Narges, Findik, Betül, Klimiankou, Maksim, Ritter, Malte, Hartmann, Marcus D., Gloeckner, Christian Johannes, Stefanczyk, Sylwia, Lindner, Christian, Oswald, Benedikt, Bernhard, Regine, Hähnel, Karin, Hermanutz-Klein, Ursula, Ebinger, Martin, Handgretinger, Rupert, Casadei, Nicolas, Welte, Karl, Andre, Maya, Müller, Patrick, Bajoghli, Baubak, Skokowa, Julia
Published in Blood (03.10.2019)
Published in Blood (03.10.2019)
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Journal Article
Phenotypic and functional immune attributes predicting survival in very elderly people (47.7)
Pawelec, Graham, Maier, Andrea, Hähnel, Karin, Zelba, Henning, de Craen, Anton, Roelofs, Helene, Slagboom, Eline, Westendorp, Rudi, Derhovanessian, Evelyna
Published in The Journal of immunology (1950) (01.05.2012)
Published in The Journal of immunology (1950) (01.05.2012)
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Journal Article
In vitro senescence models for human T lymphocytes
Pawelec, Graham, Adibzadeh, Medi, Rehbein, Arnika, Hähnel, Karin, Wagner, Wolfgang, Engel, Andrea
Published in Vaccine (25.02.2000)
Published in Vaccine (25.02.2000)
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Conference Proceeding
Extrathymic T cell differentiation in vitro from human CD34+ stem cells
Pawelec, Graham, Muller, Robert, Rehbein, Arnika, Hähnel, Karin, Ziegler, Benedikt L.
Published in Journal of leukocyte biology (01.12.1998)
Published in Journal of leukocyte biology (01.12.1998)
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