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Synthesis of CID-cleavable protein crosslinking agents containing quaternary amines for structural mass spectrometry
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Synthesis and biological activity of 5-amino- and 5-hydroxyquinolones, and the overwhelming influence of the remote N1-substituent in determining the structure-activity relationship
Domagala, John M, Bridges, Alex J, Culbertson, Townley P, Gambino, Laura, Hagen, Susan E, Karrick, Gregory, Porter, Kenneth, Sanchez, Joseph P, Sesnie, Josephine A
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4-Hydroxy-5,6-dihydropyrones as Inhibitors of HIV Protease: The Effect of Heterocyclic Substituents at C-6 on Antiviral Potency and Pharmacokinetic Parameters
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New quinolone antibacterial agents. Synthesis and biological activity of 7-(3,3- or 3,4-disubstituted-1-pyrrolidinyl)quinoline-3-carboxylic acids
Hagen, Susan E, Domagala, John M, Heifetz, Carl L, Sanchez, Joseph P, Solomon, Marjorie
Published in Journal of medicinal chemistry (01.02.1990)
Published in Journal of medicinal chemistry (01.02.1990)
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5,6-Dihydropyran-2-ones Possessing Various Sulfonyl Functionalities: Potent Nonpeptidic Inhibitors of HIV Protease
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A Novel Nonpeptide HIV-1 Protease Inhibitor: Elucidation of the Binding Mode and Its Application in the Design of Related Analogs
Lunney, Elizabeth A, Hagen, Susan E, Domagala, John M, Humblet, Christine, Kosinski, Janet, Tait, Bradley D, Warmus, Joseph S, Wilson, Michael, Ferguson, Donna
Published in Journal of medicinal chemistry (01.08.1994)
Published in Journal of medicinal chemistry (01.08.1994)
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Synthesis of CID-cleavable protein crosslinking agents containing quaternary amines for structural mass spectrometryElectronic supplementary information (ESI) available. See DOI: 10.1039/c8ob00329g
Hagen, Susan E, Liu, Kun, Jin, Yafei, Piersimoni, Lolita, Andrews, Philip C, Showalter, Hollis D
Year of Publication 26.09.2018
Year of Publication 26.09.2018
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Novel benzthiodiazepinones as antiherpetic agents: SAR improvement of therapeutic index by alterations of the seven-membered ring
HAMILTON, Harriet W, NISHIGUCHI, Gisele, IKEDA, Satoru, WATANABE, Wataru, HAGEN, Susan E, DOMAGALA, John D, WEBER, Peter C, GRACHECK, Stephen, BOULWARE, Stefanie L, NORDBY, Eric C, CHO, Hidetsura, NAKAMURA, Takeshi
Published in Bioorganic & medicinal chemistry letters (21.10.2002)
Published in Bioorganic & medicinal chemistry letters (21.10.2002)
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Quinolone antibacterial agents. Synthesis and structure-activity relationships of 8-substituted quinoline-3-carboxylic acids and 1,8-naphthyridine-3-carboxylic acids
Sanchez, Joseph P, Domagala, John M, Hagen, Susan E, Heifetz, Carl L, Hutt, Marland P, Nichols, Jeffry B, Trehan, Ashok K
Published in Journal of medicinal chemistry (01.05.1988)
Published in Journal of medicinal chemistry (01.05.1988)
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Quinolone antibacterials containing the new 7-[3-(1-aminoethyl)-1-pyrrolidinyl] side chain: the effects of the 1-aminoethyl moiety and its stereochemical configurations on potency and in vivo efficacy
Domagala, John M, Hagen, Susan E, Joannides, Themis, Kiely, John S, Laborde, Edgardo, Schroeder, Mel C, Sesnie, Josephine A, Shapiro, Martin A, Suto, Mark J, Vanderroest, Steven
Published in Journal of medicinal chemistry (01.04.1993)
Published in Journal of medicinal chemistry (01.04.1993)
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