Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia
Li, Feng, Fushima, Tomofumi, Oyanagi, Gen, Townley-Tilson, H. W. Davin, Sato, Emiko, Nakada, Hironobu, Oe, Yuji, Hagaman, John R., Wilder, Jennifer, Li, Manyu, Sekimoto, Akiyo, Saigusa, Daisuke, Sato, Hiroshi, Ito, Sadayoshi, Jennette, J. Charles, Maeda, Nobuyo, Karumanchi, S. Ananth, Smithies, Oliver, Takahashi, Nobuyuki
Published in Proceedings of the National Academy of Sciences - PNAS (22.11.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (22.11.2016)
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eNOS Deficiency Acts through Endothelin to Aggravate sFlt-1―Induced Pre-Eclampsia―Like Phenotype
FENG LI, HAGAMAN, John R, KIM, Hyung-Suk, MAEDA, Nobuyo, CHARLES JENNETTE, J, FABER, James E, ANANTH KARUMANCHI, S, SMITHIES, Oliver, TAKAHASHI, Nobuyuki
Published in Journal of the American Society of Nephrology (01.04.2012)
Published in Journal of the American Society of Nephrology (01.04.2012)
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Endothelin-1 critically influences cardiac function via superoxide-MMP9 cascade
Hathaway, Catherine K., Grant, Ruriko, Hagaman, John R., Hiller, Sylvia, Li, Feng, Xu, Longquan, Chang, Albert S., Madden, Victoria J., Bagnell, C. Robert, Rojas, Mauricio, Kim, Hyung-Suk, Wu, Bingruo, Zhou, Bin, Smithies, Oliver, Kakoki, Masao
Published in Proceedings of the National Academy of Sciences - PNAS (21.04.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (21.04.2015)
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Cyanocobalamin prevents cardiomyopathy in type 1 diabetes by modulating oxidative stress and DNMT-SOCS1/3-IGF-1 signaling
Kakoki, Masao, Ramanathan, Purushotham V., Hagaman, John R., Grant, Ruriko, Wilder, Jennifer C., Taylor, Joan M., Charles Jennette, J., Smithies, Oliver, Maeda-Smithies, Nobuyo
Published in Communications biology (23.06.2021)
Published in Communications biology (23.06.2021)
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Primary aldosteronism and impaired natriuresis in mice underexpressing TGFβ1
Kakoki, Masao, Pochynyuk, Oleh M., Hathaway, Catherine M., Tomita, Hirofumi, Hagaman, John R., Kim, Hyung-Suk, Zaika, Oleg L., Mamenko, Mykola, Kayashima, Yukako, Matsuki, Kota, Hiller, Sylvia, Li, Feng, Xu, Longquan, Grant, Ruriko, Bertorello, Alejandro M., Smithies, Oliver
Published in Proceedings of the National Academy of Sciences - PNAS (02.04.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (02.04.2013)
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A Noninvasive Computerized Tail-Cuff System for Measuring Blood Pressure in Mice
Krege, John H, Hodgin, Jeffrey B, Hagaman, John R, Smithies, Oliver
Published in Hypertension (Dallas, Tex. 1979) (01.05.1995)
Published in Hypertension (Dallas, Tex. 1979) (01.05.1995)
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Angiotensin-Converting Enzyme and Male Fertility
Hagaman, John R., Moyer, Jeffrey S., Bachman, Eric S., Sibony, Mathilde, Magyar, Patricia L., Welch, Jeffrey E., Smithies, Oliver, Krege, John H., O'Brien, Deborah A.
Published in Proceedings of the National Academy of Sciences - PNAS (03.03.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (03.03.1998)
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Genetic Decreases in Atrial Natriuretic Peptide and Salt-Sensitive Hypertension
Simon W. M. John, Krege, John H., Oliver, Paula M., Hagaman, John R., Hodgin, Jeffrey B., Pang, Stephen C., Flynn, T. Geoffrey, Smithies, Oliver
Published in Science (American Association for the Advancement of Science) (03.02.1995)
Published in Science (American Association for the Advancement of Science) (03.02.1995)
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Minireview: Computer Simulations of Blood Pressure Regulation by the Renin-Angiotensin System
Takahashi, Nobuyuki, Hagaman, John R, Kim, Hyung-Suk, Smithies, Oliver
Published in Endocrinology (Philadelphia) (01.06.2003)
Published in Endocrinology (Philadelphia) (01.06.2003)
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Cardiac Hypertrophy and Sudden Death in Mice with a Genetically Clamped Renin Transgene
Kathleen M. I. Caron, James, Leighton R., Kim, Hyung-Suk, Knowles, Josh, Uhlir, Rick, Mao, Lan, Hagaman, John R., Cascio, Wayne, Rockman, Howard, Smithies, Oliver
Published in Proceedings of the National Academy of Sciences - PNAS (02.03.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (02.03.2004)
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Differences in aortic arch geometry, hemodynamics, and plaque patterns between C57BL/6 and 129/SvEv mice
Zhu, Hui, Zhang, Ji, Shih, Jessica, Lopez-Bertoni, Federico, Hagaman, John R, Maeda, Nobuyo, Friedman, Morton H
Published in Journal of biomechanical engineering (01.12.2009)
Published in Journal of biomechanical engineering (01.12.2009)
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Engulfment and cell motility protein 1 potentiates diabetic cardiomyopathy via Rac-dependent and Rac-independent ROS production
Kakoki, Masao, Bahnson, Edward M, Hagaman, John R, Siletzky, Robin M, Grant, Ruriko, Kayashima, Yukako, Li, Feng, Lee, Esther Y, Sun, Michelle T, Taylor, Joan M, Rice, Jessica C, Almeida, Michael F, Bahr, Ben A, Jennette, J Charles, Smithies, Oliver, Maeda-Smithies, Nobuyo
Published in JCI insight (20.06.2019)
Published in JCI insight (20.06.2019)
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Male-female differences in fertility and blood pressure in ACE-deficient mice
Krege, John H, John, Simon W. M, Langenbach, Laura L, Hodgin, Jeffrey B, Hagaman, John R, Bachman, Eric S, Jennette, J. Charles, O'Brien, Deborah A, Smithies, Oliver
Published in Nature (London) (11.05.1995)
Published in Nature (London) (11.05.1995)
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Genetic Control of Blood Pressure and the Angiotensinogen Locus
Kim, Hyung-Suk, Krege, John H., Kluckman, Kimberly D., Hagaman, John R., Hodgin, Jeffrey B., Best, Christopher F., Jennette, Charles, Coffman, Thomas M., Maeda, Nobuyo, Smithies, Oliver
Published in Proceedings of the National Academy of Sciences - PNAS (28.03.1995)
Published in Proceedings of the National Academy of Sciences - PNAS (28.03.1995)
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In vivo response to vascular injury in the absence of factor IX: Examination in factor IX knockout mice
Gui, Tong, Reheman, Adili, Funkhouser, William K, Bellinger, Dwight A, Hagaman, John R, Stafford, Darrel W, Monahan, Paul E, Ni, Heyu
Published in Thrombosis research (2007)
Published in Thrombosis research (2007)
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Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A–deficient mice
Knowles, Joshua W., Esposito, Giovanni, Mao, Lan, Hagaman, John R., Fox, Jennifer E., Smithies, Oliver, Rockman, Howard A., Maeda, Nobuyo
Published in The Journal of clinical investigation (15.04.2001)
Published in The Journal of clinical investigation (15.04.2001)
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Journal Article
Increased susceptibility to heart failure in response to volume overload in mice lacking natriuretic peptide receptor-A gene
NISHIKIMI, Toshio, HAGAMAN, John R, TAKAHASHI, Nobuyuki, KIM, Hyung-Suk, MATSUOKA, Hiroaki, SMITHIES, Oliver, MAEDA, Nobuyo
Published in Cardiovascular research (01.04.2005)
Published in Cardiovascular research (01.04.2005)
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Hypertension and abnormal fat distribution but not insulin resistance in mice with P465L PPARγ
Tsai, Yau-Sheng, Kim, Hyo-Jeong, Takahashi, Nobuyuki, Kim, Hyung-Suk, Hagaman, John R., Kim, Jason K., Maeda, Nobuyo
Published in The Journal of clinical investigation (15.07.2004)
Published in The Journal of clinical investigation (15.07.2004)
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Journal Article
Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice
Knowles, J W, Esposito, G, Mao, L, Hagaman, J R, Fox, J E, Smithies, O, Rockman, H A, Maeda, N
Published in The Journal of clinical investigation (01.04.2001)
Published in The Journal of clinical investigation (01.04.2001)
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