Vascularised cardiac spheroids-on-a-chip for testing the toxicity of therapeutics
Di Cio, Stefania, Marhuenda, Emilie, Haddrick, Malcolm, Gautrot, Julien E.
Published in Scientific reports (09.02.2024)
Published in Scientific reports (09.02.2024)
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Journal Article
Understanding Cytotoxicity and Cytostaticity in a High-Throughput Screening Collection
Mervin, Lewis H, Cao, Qing, Barrett, Ian P, Firth, Mike A, Murray, David, McWilliams, Lisa, Haddrick, Malcolm, Wigglesworth, Mark, Engkvist, Ola, Bender, Andreas
Published in ACS chemical biology (18.11.2016)
Published in ACS chemical biology (18.11.2016)
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Journal Article
Mesothelial Cells Exhibit Characteristics of Perivascular Cells in an In Vitro Angiogenesis Assay
Koukorava, Chrysa, Ward, Kelly, Ahmed, Katie, Almaghrabi, Shrouq, Dauleh, Sumaya, Pereira, Sofia M, Taylor, Arthur, Haddrick, Malcolm, Cross, Michael J, Wilm, Bettina
Published in Cells (Basel, Switzerland) (01.10.2023)
Published in Cells (Basel, Switzerland) (01.10.2023)
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Journal Article
Modeling the mechanical stiffness of pancreatic ductal adenocarcinoma
Kpeglo, Delanyo, Hughes, Matthew D.G., Dougan, Lorna, Haddrick, Malcolm, Knowles, Margaret A., Evans, Stephen D., Peyman, Sally A.
Published in Matrix biology plus (01.06.2022)
Published in Matrix biology plus (01.06.2022)
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Journal Article
Modelling and breaking down the biophysical barriers to drug delivery in pancreatic cancer
Kpeglo, Delanyo, Haddrick, Malcolm, Knowles, Margaret A, Evans, Stephen D, Peyman, Sally A
Published in Lab on a chip (13.02.2024)
Published in Lab on a chip (13.02.2024)
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Journal Article
A novel, label-free system to interrogate the function and 3D phenotype of iPSC cardiomyocyte co-culture spheroids for discovery applications
Burnham, Matthew, Harvey, Rachel, Thomas, Ulrich, Fertig, Niels, Haddrick, Malcolm
Published in Journal of pharmacological and toxicological methods (01.09.2018)
Published in Journal of pharmacological and toxicological methods (01.09.2018)
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Journal Article
A Scalable Approach Reveals Functional Responses of iPSC Cardiomyocyte 3D Spheroids
Burnham, Matthew P., Harvey, Rachel, Sargeant, Rebecca, Fertig, Niels, Haddrick, Malcolm
Published in SLAS discovery (01.03.2021)
Published in SLAS discovery (01.03.2021)
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Journal Article
A Study of the Dimerization of Rous Sarcoma Virus RNA in Vitro and in Vivo
Lear, Andrew L., Haddrick, Malcolm, Heaphy, Shaun
Published in Virology (New York, N.Y.) (10.09.1995)
Published in Virology (New York, N.Y.) (10.09.1995)
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Journal Article
Biologic Studies of Chimeras of Highly and Moderately Virulent Molecular Clones of Simian Immunodeficiency Virus SIVsmPBj Suggest a Critical Role for Envelope in Acute AIDS Virus Pathogenesis
Haddrick, Malcolm, Brown, Charles R., Plishka, Ronald, Buckler-White, Alicia, Hirsch, Vanessa M., Ginsberg, Harold
Published in Journal of Virology (01.07.2001)
Published in Journal of Virology (01.07.2001)
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Journal Article
Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumor drug accumulation and limiting bioavailability and toxicity in normal tissues
Ingram, Nicola, McVeigh, Laura E, Abou-Saleh, Radwa H, Maynard, Juliana, Peyman, Sally A, McLaughlan, James R, Fairclough, Michael, Marston, Gemma, Valleley, Elizabeth M A, Jimenez-Macias, Jorge L, Charalambous, Antonia, Townley, William, Haddrick, Malcolm, Wierzbicki, Antonia, Wright, Alexander, Volpato, Milène, Simpson, Peter B, Treanor, Darren E, Thomson, Neil H, Loadman, Paul M, Bushby, Richard J, Johnson, Benjamin R G, Jones, Pamela F, Evans, J Anthony, Freear, Steven, Markham, Alexander F, Evans, Stephen D, Coletta, P Louise
Published in Theranostics (01.01.2020)
Published in Theranostics (01.01.2020)
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Journal Article
Structure‐Based Design of Selective Noncovalent CDK12 Inhibitors
Johannes, Jeffrey W., Denz, Christopher R., Su, Nancy, Wu, Allan, Impastato, Anna C., Mlynarski, Scott, Varnes, Jeffrey G., Prince, D. Bryan, Cidado, Justin, Gao, Ning, Haddrick, Malcolm, Jones, Natalie H., Li, Shaobin, Li, Xiuwei, Liu, Yang, Nguyen, Toan B., O'Connell, Nichole, Rivers, Emma, Robbins, Daniel W., Tomlinson, Ronald, Yao, Tieguang, Zhu, Xiahui, Ferguson, Andrew D., Lamb, Michelle L., Manchester, John I., Guichard, Sylvie
Published in ChemMedChem (06.02.2018)
Published in ChemMedChem (06.02.2018)
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Journal Article
A fluorescent BSEP inhibition assay: A novel in vitro tool for predictive toxicology
Munro, Kirsten M., Walker, Clare L., Stahl, Simone, Dawson, Sarah, Kenna, Gerry, Brown, Dearg, Haddrick, Malcolm, Valentin, Jean- Pierre
Published in Journal of pharmacological and toxicological methods (01.07.2011)
Published in Journal of pharmacological and toxicological methods (01.07.2011)
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Journal Article
Cryopreservation of HepG2 and H4-II-E-c3 cells for use in high content biology assays
Thompson, Emma L., Atwal, Saseela, Brown, Martin R., Sharpe, Paul M., Jones, Darren I., Haddrick, Malcolm, Valentin, Jean-Pierre
Published in Journal of pharmacological and toxicological methods (01.07.2011)
Published in Journal of pharmacological and toxicological methods (01.07.2011)
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Journal Article
Evidence that a Kissing Loop Structure Facilitates Genomic RNA Dimerisation in HIV-1
Haddrick, Malcolm, Lear, Andrew L., Cann, Alan J., Heaphy, Shaun
Published in Journal of molecular biology (31.05.1996)
Published in Journal of molecular biology (31.05.1996)
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Journal Article