The Role of Mitochondrially Derived ATP in Synaptic Vesicle Recycling
Pathak, Divya, Shields, Lauren Y., Mendelsohn, Bryce A., Haddad, Dominik, Lin, Wei, Gerencser, Akos A., Kim, Hwajin, Brand, Martin D., Edwards, Robert H., Nakamura, Ken
Published in The Journal of biological chemistry (11.09.2015)
Published in The Journal of biological chemistry (11.09.2015)
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Journal Article
PINK1 Loss-of-Function Mutations Affect Mitochondrial Complex I Activity via NdufA10 Ubiquinone Uncoupling
Morais, Vanessa A., Haddad, Dominik, Craessaerts, Katleen, De Bock, Pieter-Jan, Swerts, Jef, Vilain, Sven, Aerts, Liesbeth, Overbergh, Lut, Grünewald, Anne, Seibler, Philip, Klein, Christine, Gevaert, Kris, Verstreken, Patrik, De Strooper, Bart
Published in Science (American Association for the Advancement of Science) (11.04.2014)
Published in Science (American Association for the Advancement of Science) (11.04.2014)
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Journal Article
Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration
Linsley, Jeremy W., Shah, Kevan, Castello, Nicholas, Chan, Michelle, Haddad, Dominik, Doric, Zak, Wang, Shijie, Leks, Wiktoria, Mancini, Jay, Oza, Viral, Javaherian, Ashkan, Nakamura, Ken, Kokel, David, Finkbeiner, Steven
Published in Nature communications (06.09.2021)
Published in Nature communications (06.09.2021)
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Journal Article
Vitamin K₂ Is a Mitochondrial Electron Carrier That Rescues Pink1 Deficiency
Vos, Melissa, Esposito, Giovanni, Edirisinghe, Janaka N., Vilain, Sven, Haddad, Dominik M., Slabbaert, Jan R., Van Meensel, Stefanie, Schaap, Onno, De Strooper, Bart, Meganathan, R., Morais, Vanessa A., Verstreken, Patrik
Published in Science (American Association for the Advancement of Science) (08.06.2012)
Published in Science (American Association for the Advancement of Science) (08.06.2012)
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Journal Article
Mutations in the Intellectual Disability Gene Ube2a Cause Neuronal Dysfunction and Impair Parkin-Dependent Mitophagy
Haddad, Dominik M., Vilain, Sven, Vos, Melissa, Esposito, Giovanni, Matta, Samer, Kalscheuer, Vera M., Craessaerts, Katleen, Leyssen, Maarten, Nascimento, Rafaella M.P., Vianna-Morgante, Angela M., De Strooper, Bart, Van Esch, Hilde, Morais, Vanessa A., Verstreken, Patrik
Published in Molecular cell (27.06.2013)
Published in Molecular cell (27.06.2013)
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Journal Article
Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function
Morais, Vanessa A., Verstreken, Patrik, Roethig, Anne, Smet, Joél, Snellinx, An, Vanbrabant, Mieke, Haddad, Dominik, Frezza, Christian, Mandemakers, Wim, Vogt‐Weisenhorn, Daniela, Van Coster, Rudy, Wurst, Wolfgang, Scorrano, Luca, De Strooper, Bart
Published in EMBO molecular medicine (01.05.2009)
Published in EMBO molecular medicine (01.05.2009)
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Journal Article
The yeast complex I equivalent NADH dehydrogenase rescues pink1 mutants
Vilain, Sven, Esposito, Giovanni, Haddad, Dominik, Schaap, Onno, Dobreva, Mariya P, Vos, Melissa, Van Meensel, Stefanie, Morais, Vanessa A, De Strooper, Bart, Verstreken, Patrik
Published in PLoS genetics (01.01.2012)
Published in PLoS genetics (01.01.2012)
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Journal Article
The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy
Cornelissen, Tom, Haddad, Dominik, Wauters, Fieke, Van Humbeeck, Cindy, Mandemakers, Wim, Koentjoro, Brianada, Sue, Carolyn, Gevaert, Kris, De Strooper, Bart, Verstreken, Patrik, Vandenberghe, Wim
Published in Human Molecular Genetics (01.10.2014)
Published in Human Molecular Genetics (01.10.2014)
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Journal Article
Web Resource
Isoflurane inhibition of endocytosis is an anesthetic mechanism of action
Jung, Sangwook, Zimin, Pavel I., Woods, Christian B., Kayser, Ernst-Bernhard, Haddad, Dominik, Reczek, Colleen R., Nakamura, Ken, Ramirez, Jan-Marino, Sedensky, Margaret M., Morgan, Philip G.
Published in Current biology (25.07.2022)
Published in Current biology (25.07.2022)
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Journal Article
LRRK2 Controls an EndoA Phosphorylation Cycle in Synaptic Endocytosis
Matta, Samer, Van Kolen, Kristof, da Cunha, Raquel, van den Bogaart, Geert, Mandemakers, Wim, Miskiewicz, Katarzyna, De Bock, Pieter-Jan, Morais, Vanessa A., Vilain, Sven, Haddad, Dominik, Delbroek, Lore, Swerts, Jef, Chávez-Gutiérrez, Lucía, Esposito, Giovanni, Daneels, Guy, Karran, Eric, Holt, Matthew, Gevaert, Kris, Moechars, Diederik W., De Strooper, Bart, Verstreken, Patrik
Published in Neuron (Cambridge, Mass.) (20.09.2012)
Published in Neuron (Cambridge, Mass.) (20.09.2012)
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Journal Article
Mitochondrial fission is a critical modulator of mutant APP-induced neural toxicity
Shields, Lauren Y., Li, Huihui, Nguyen, Kevin, Kim, Hwajin, Doric, Zak, Garcia, Joseph H., Gill, T. Michael, Haddad, Dominik, Vossel, Keith, Calvert, Meredith, Nakamura, Ken
Published in The Journal of biological chemistry (01.01.2021)
Published in The Journal of biological chemistry (01.01.2021)
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Journal Article
Vitamin K 2 Is a Mitochondrial Electron Carrier That Rescues Pink1 Deficiency
Vos, Melissa, Esposito, Giovanni, Edirisinghe, Janaka N., Vilain, Sven, Haddad, Dominik M., Slabbaert, Jan R., Van Meensel, Stefanie, Schaap, Onno, De Strooper, Bart, Meganathan, R., Morais, Vanessa A., Verstreken, Patrik
Published in Science (American Association for the Advancement of Science) (08.06.2012)
Published in Science (American Association for the Advancement of Science) (08.06.2012)
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Journal Article
Chronic hyperactivation of midbrain dopamine neurons causes preferential dopamine neuron degeneration
Rademacher, Katerina, Doric, Zak, Haddad, Dominik, Mamaligas, Aphroditi, Liao, Szu-Chi, Creed, Rose B, Kano, Kohei, Chatterton, Zac, Fu, Yuhong, Garcia, Joseph H, Vance, Victoria, Sei, Yoshitaka, Kreitzer, Anatol, Halliday, Glenda M, Nelson, Alexandra B, Margolis, Elyssa B, Nakamura, Ken
Published in bioRxiv (13.05.2024)
Published in bioRxiv (13.05.2024)
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Journal Article
Lysosomes and Mitophagy
Haddad, Dominik, Verstreken, Patrik
Published in Lysosomes: Biology, Diseases, and Therapeutics (27.06.2016)
Published in Lysosomes: Biology, Diseases, and Therapeutics (27.06.2016)
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