Distinct Neural Stem Cell Populations Give Rise to Disparate Brain Tumors in Response to N-MYC
Swartling, Fredrik J., Savov, Vasil, Persson, Anders I., Chen, Justin, Hackett, Christopher S., Northcott, Paul A., Grimmer, Matthew R., Lau, Jasmine, Chesler, Louis, Perry, Arie, Phillips, Joanna J., Taylor, Michael D., Weiss, William A.
Published in Cancer cell (15.05.2012)
Published in Cancer cell (15.05.2012)
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Journal Article
Engineering strategies to overcome the current roadblocks in CAR T cell therapy
Rafiq, Sarwish, Hackett, Christopher S, Brentjens, Renier J
Published in Nature reviews. Clinical oncology (01.03.2020)
Published in Nature reviews. Clinical oncology (01.03.2020)
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Journal Article
Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics
Huang, Xi, Dubuc, Adrian M, Hashizume, Rintaro, Berg, Jim, He, Ye, Wang, Ji, Chiang, Chin, Cooper, Michael K, Northcott, Paul A, Taylor, Michael D, Barnes, Michael J, Tihan, Tarik, Chen, Justin, Hackett, Christopher S, Weiss, William A, James, C David, Rowitch, David H, Shuman, Marc A, Jan, Yuh Nung, Jan, Lily Yeh
Published in Genes & development (15.08.2012)
Published in Genes & development (15.08.2012)
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Journal Article
Paracrine signaling through MYCN enhances tumor-vascular interactions in neuroblastoma
Chanthery, Yvan H, Gustafson, W Clay, Itsara, Melissa, Persson, Anders, Hackett, Christopher S, Grimmer, Matt, Charron, Elise, Yakovenko, Slava, Kim, Grace, Matthay, Katherine K, Weiss, William A
Published in Science translational medicine (04.01.2012)
Published in Science translational medicine (04.01.2012)
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Journal Article
Expression Quantitative Trait Loci and Receptor Pharmacology Implicate Arg1 and the GABA-A Receptor as Therapeutic Targets in Neuroblastoma
Hackett, Christopher S., Quigley, David A., Wong, Robyn A., Chen, Justin, Cheng, Christine, Song, Young K., Wei, Jun S., Pawlikowska, Ludmila, Bao, Yun, Goldenberg, David D., Nguyen, Kim, Gustafson, W. Clay, Rallapalli, Sundari K., Cho, Yoon-Jae, Cook, James M., Kozlov, Serguei, Mao, Jian-Hua, Van Dyke, Terry, Kwok, Pui-Yan, Khan, Javed, Balmain, Allan, Fan, QiWen, Weiss, William A.
Published in Cell reports (Cambridge) (06.11.2014)
Published in Cell reports (Cambridge) (06.11.2014)
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Journal Article
The genetics of splicing in neuroblastoma
Chen, Justin, Hackett, Christopher S, Zhang, Shile, Song, Young K, Bell, Robert J A, Molinaro, Annette M, Quigley, David A, Balmain, Allan, Song, Jun S, Costello, Joseph F, Gustafson, W Clay, Van Dyke, Terry, Kwok, Pui-Yan, Khan, Javed, Weiss, William A
Published in Cancer discovery (01.04.2015)
Published in Cancer discovery (01.04.2015)
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Journal Article
Fundamental differences in promoter CpG island DNA hypermethylation between human cancer and genetically engineered mouse models of cancer
Diede, Scott J, Yao, Zizhen, Keyes, C Chip, Tyler, Ashlee E, Dey, Joyoti, Hackett, Christopher S, Elsaesser, Katrina, Kemp, Christopher J, Neiman, Paul E, Weiss, William A, Olson, James M, Tapscott, Stephen J
Published in Epigenetics (01.12.2013)
Published in Epigenetics (01.12.2013)
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Journal Article
Multipurposing CARs: Same engine, different vehicles
Hossian, A.K.M. Nawshad, Hackett, Christopher S., Brentjens, Renier J., Rafiq, Sarwish
Published in Molecular therapy (06.04.2022)
Published in Molecular therapy (06.04.2022)
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Journal Article
Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis
Vaishnavi, Aria, Juan, Joseph, Jacob, Maebh, Stehn, Christopher, Gardner, Eric E, Scherzer, Michael T, Schuman, Sophia, Van Veen, J Edward, Murphy, Brandon, Hackett, Christopher S, Dupuy, Adam J, Chmura, Steven A, van der Weyden, Louise, Newberg, Justin Y, Liu, Annie, Mann, Karen, Rust, Alistair G, Weiss, William A, Kinsey, Conan G, Adams, David J, Grossmann, Allie, Mann, Michael B, McMahon, Martin
Published in Cancer research (Chicago, Ill.) (15.11.2022)
Published in Cancer research (Chicago, Ill.) (15.11.2022)
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Journal Article
miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN -amplified neuroblastoma
Swarbrick, Alexander, Goga, Andrei, Woods, Susan L, Shaw, Alexander, Balakrishnan, Asha, Phua, Yuwei, Nguyen, Akira, Chanthery, Yvan, Lim, Lionel, Ashton, Lesley J, Judson, Robert L, Huskey, Noelle, Blelloch, Robert, Haber, Michelle, Norris, Murray D, Lengyel, Peter, Hackett, Christopher S, Preiss, Thomas, Chetcuti, Albert, Sullivan, Christopher S, Marcusson, Eric G, Weiss, William, L'Etoile, Noelle
Published in Nature medicine (01.10.2010)
Published in Nature medicine (01.10.2010)
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Journal Article
Pleiotropic role for MYCN in medulloblastoma
Swartling, Fredrik J, Grimmer, Matthew R, Hackett, Christopher S, Northcott, Paul A, Fan, Qi-Wen, Goldenberg, David D, Lau, Jasmine, Masic, Selma, Nguyen, Kim, Yakovenko, Slava, Zhe, Xiao-Ning, Gilmer, Heather C Flynn, Collins, Rodney, Nagaoka, Mai, Phillips, Joanna J, Jenkins, Robert B, Tihan, Tarik, Vandenberg, Scott R, James, C David, Tanaka, Kohichi, Taylor, Michael D, Weiss, William A, Chesler, Louis
Published in Genes & development (15.05.2010)
Published in Genes & development (15.05.2010)
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Journal Article
A dual phosphoinositide-3-kinase alpha/mTOR inhibitor cooperates with blockade of epidermal growth factor receptor in PTEN-mutant glioma
Fan, Qi-Wen, Cheng, Christine K, Nicolaides, Theodore P, Hackett, Christopher S, Knight, Zachary A, Shokat, Kevan M, Weiss, William A
Published in Cancer research (Chicago, Ill.) (01.09.2007)
Published in Cancer research (Chicago, Ill.) (01.09.2007)
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Journal Article
Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethality
Collier, Lara S, Adams, David J, Hackett, Christopher S, Bendzick, Laura E, Akagi, Keiko, Davies, Michael N, Diers, Miechaleen D, Rodriguez, Fausto J, Bender, Aaron M, Tieu, Christina, Matise, Ilze, Dupuy, Adam J, Copeland, Neal G, Jenkins, Nancy A, Hodgson, J Graeme, Weiss, William A, Jenkins, Robert B, Largaespada, David A
Published in Cancer research (Chicago, Ill.) (01.11.2009)
Published in Cancer research (Chicago, Ill.) (01.11.2009)
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Journal Article
Structure-based prediction of insertion-site preferences of transposons into chromosomes
Geurts, Aron M., Hackett, Christopher S., Bell, Jason B., Bergemann, Tracy L., Collier, Lara S., Carlson, Corey M., Largaespada, David A., Hackett, Perry B.
Published in Nucleic acids research (01.01.2006)
Published in Nucleic acids research (01.01.2006)
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Journal Article
Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors
HACKETT, Christopher S, HODGSON, J. Graeme, JENKINS, Robert, GRAY, Joe W, WEISS, William A, LAW, Mark E, FRIDLYAND, Jane, OSOEGAWA, Kazutoyo, DE JONG, Pieter J, NOWAK, Norma J, PINKEL, Daniel, ALBERTSON, Donna G, JAIN, Ajay
Published in Cancer research (Chicago, Ill.) (01.09.2003)
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Published in Cancer research (Chicago, Ill.) (01.09.2003)
Journal Article
Cell lines from MYCN transgenic murine tumours reflect the molecular and biological characteristics of human neuroblastoma
Cheng, Andy J, Ching Cheng, Ngan, Ford, Jette, Smith, Janice, Murray, Jayne E, Flemming, Claudia, Lastowska, Maria, Jackson, Michael S, Hackett, Christopher S, Weiss, William A, Marshall, Glenn M, Kees, Ursula R, Norris, Murray D, Haber, Michelle
Published in European journal of cancer (1990) (01.06.2007)
Published in European journal of cancer (1990) (01.06.2007)
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Journal Article
TYRP1 directed CAR T cells control tumor progression in preclinical melanoma models
Hackett, Christopher S., Hirschhorn, Daniel, Tang, Meixian S., Purdon, Terence J., Marouf, Yacine, Piersigilli, Alessandra, Agaram, Narasimhan P., Liu, Cailian, Schad, Sara E., de Stanchina, Elisa, Rafiq, Sarwish, Monette, Sebastien, Wolchok, Jedd D., Merghoub, Taha, Brentjens, Renier J.
Published in Molecular Therapy Oncology (19.09.2024)
Published in Molecular Therapy Oncology (19.09.2024)
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Journal Article
CAR-engineered lymphocyte persistence is governed by a FAS ligand/FAS auto-regulatory circuit
Yi, Fei, Cohen, Tal, Zimmerman, Natalie, Dündar, Friederike, Zumbo, Paul, Eltilib, Razan, Brophy, Erica J, Arkin, Hannah, Feucht, Judith, Gormally, Michael V, Hackett, Christopher S, Kropp, Korbinian N, Etxeberria, Inaki, Chandran, Smita S, Park, Jae H, Hsu, Katharine C, Sadelain, Michel, Betel, Doron, Klebanoff, Christopher A
Published in bioRxiv (01.03.2024)
Published in bioRxiv (01.03.2024)
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