Multiple mechanisms confer drug resistance to mitoxantrone in the human 8226 myeloma cell line
HAZLEHURST, L. A, FOLEY, N. E, GLEASON-GUZMAN, M. C, HACKER, M. P, CRESS, A. E, GREENBERGER, L. W, DE JONG, M. C, DALTON, W. S
Published in Cancer research (Chicago, Ill.) (01.03.1999)
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Published in Cancer research (Chicago, Ill.) (01.03.1999)
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Cytotoxicity and antitumor activity of bis(platinum) complexes. A novel class of platinum complexes active in cell lines resistant to both cisplatin and 1,2-diaminocyclohexane complexes
Farrell, Nicholas, Qu, Yun, Hacker, Miles P
Published in Journal of medicinal chemistry (01.08.1990)
Published in Journal of medicinal chemistry (01.08.1990)
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Synthesis and Antitumor Evaluation of 2,5-Disubstituted- Indazolo[4,3-g h]isoquinolin-6(2H)-ones (9-Aza-anthrapyrazoles)
Krapcho, A. Paul, Menta, Ernesto, Oliva, Ambrogio, Di Domenico, Roberto, Fiocchi, Luigi, Maresch, Martin E, Gallagher, Cynthia E, Hacker, Miles P, Beggiolin, Gino, Giuliani, Fernando C, Pezzoni, Gabriella, Spinelli, Silvano
Published in Journal of medicinal chemistry (31.12.1998)
Published in Journal of medicinal chemistry (31.12.1998)
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Mechanisms of Asbestos-induced Nitric Oxide Production by Rat Alveolar Macrophages in Inhalation and in vitro Models
Quinlan, Timothy R, BeruBe, Kelly A, Hacker, Miles P, Taatjes, Douglas J, Timblin, Cynthia R, Goldberg, Jonathan, Kimberley, Priscilla, O’Shaughnessy, Patrick, Hemenway, David, Torino, Jennifer, Jimenez, Luis A, Mossman, Brooke T
Published in Free radical biology & medicine (15.03.1998)
Published in Free radical biology & medicine (15.03.1998)
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6,9-Bis[(aminoalkyl)amino]benzo[g]isoquinoline-5,10-diones. A Novel Class of Chromophore-Modified Antitumor Anthracene-9,10-diones: Synthesis and Antitumor Evaluations
Krapcho, A. Paul, Petry, Mary E, Getahun, Zelleka, Landi, John J, Stallman, John, Polsenberg, Johanna F, Gallagher, Cynthia E, Maresch, Martin J, Hacker, Miles P
Published in Journal of medicinal chemistry (01.03.1994)
Published in Journal of medicinal chemistry (01.03.1994)
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Chemical properties and antitumor activity of complexes of platinum containing substituted sulfoxides [PtCl(R'R''SO)(diamine)]NO3. Chirality and leaving-group ability of sulfoxide affecting biological activity
Farrell, Nicholas, Kiley, Donna M, Schmidt, Wendy, Hacker, Miles P
Published in Inorganic chemistry (01.02.1990)
Published in Inorganic chemistry (01.02.1990)
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A novel aza-anthrapyrazole modulates the development of CD4+ effector T cells (P5207)
Clark, Matthew, Hacker, Miles, Quinn, Anthony
Published in The Journal of immunology (1950) (01.05.2013)
Published in The Journal of immunology (1950) (01.05.2013)
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Synthesis and antitumor evaluations of symmetrically and unsymmetrically substituted 1,4-bis[(aminoalkyl)amino]anthracene-9,10-diones and 1,4-bis[(aminoalkyl)amino]-5,8-dihydroxyanthracene-9,10-diones
Krapcho, A. Paul, Getahun, Zelleka, Avery, Kenneth L, Vargas, Kevin J, Hacker, Miles P, Spinelli, Silvano, Pezzoni, Gabriella, Manzotti, Carla
Published in Journal of medicinal chemistry (01.08.1991)
Published in Journal of medicinal chemistry (01.08.1991)
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A novel aza-anthrapyrazole blocks the progression of experimental autoimmune encephalomyelitis after the priming of autoimmunity
Kiraly, Alex, Koffman, Boyd, Hacker, Miles, Gunning, William, Rasche, Sarah, Quinn, Anthony
Published in Clinical immunology (Orlando, Fla.) (01.12.2011)
Published in Clinical immunology (Orlando, Fla.) (01.12.2011)
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Abstract 3576: Pixantrone is chemically and mechanistically related to mitoxantrone (Mito) and doxorubicin (Dox) but lacks their iron binding properties and myocyte toxicity in vitro
Hacker, Miles P., Ata, Tariq, Gesler, Korie, Mazur, Jakub, McKennon, Marc, Singer, Jack
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Dissociation of Antitumor Potency from Anthracycline Cardiotoxicity in a Doxorubicin Analog
Sikic, Branimir Ivan, Ehsan, Mohamed N., Harker, W. Graydon, Friend, Nina F., Brown, Byron W., Newman, Robert A., Hacker, Miles P., Acton, Edward M.
Published in Science (American Association for the Advancement of Science) (28.06.1985)
Published in Science (American Association for the Advancement of Science) (28.06.1985)
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