WED-365 Extended treatment of HBeAg+ CHB subjects with the Capsid assembly modulator ALG-000184 with or without Entecavir is associated with reductions in viral markers and favorable anti-HBeAb trends
Yuen, Man-Fung, Gane, Edward J., Agarwal, Kosh, Niu, Junqi, Ren, Hong, Ding, Yanhua, Liang, Xieer, Yu, Xian, Xu, Jia, Jucov, Alina, Haceatrean, Alexei, Wu, Min, Le, Kha, Maderazo, Maida, Blatt, Lawrence, Chanda, Sushmita, Lin, Tse-I, McClure, Matt, Hou, Jinlin
Published in Journal of hepatology (01.06.2024)
Published in Journal of hepatology (01.06.2024)
Get full text
Journal Article
WED-361 Dosing with the Capsid Assembly Modulator ALG-000184 in Untreated HBeAg Negative CHB Subjects Results in Potent Antiviral Effects Including Suppression of HBV DNA/RNA and Declines in HBcrAg Levels
Agarwal, Kosh, Gane, Edward J., Yuen, Man-Fung, Schwabe, Christian, Jucov, Alina, Haceatrean, Alexei, Wu, Min, Le, Kha, Maderazo, Maida, Blatt, Lawrence, Chanda, Sushmita, Lin, Tse-I, McClure, Matt
Published in Journal of hepatology (01.06.2024)
Published in Journal of hepatology (01.06.2024)
Get full text
Journal Article
Safety, pharmacokinetics, and antiviral activity of single ascending doses of ALG-125755, a GalNAc-conjugated small interfering RNA, in subjects with chronic hepatitis B
Jucov, Alina, Gane, Edward J., Fitzgerald, Megan, Le, Kha, Wang, Stanley, Ammar, Lynne, Burnett, Chris, Haceatrean, Alexei, Gupta, Kusum, Clark, Doug, Venkatraman, Meenakshi, Beigelman, Leonid, Blatt, Lawrence, Lin, Tse-I, Chanda, Sushmita, McClure, Matthew, Fry, John
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
Get full text
Journal Article
SAT-188 - Safety, pharmacokinetics, and antiviral activity of single ascending doses of ALG-125755, a GalNAc-conjugated small interfering RNA, in subjects with chronic hepatitis B
Jucov, Alina, Gane, Edward J., Fitzgerald, Megan, Le, Kha, Wang, Stanley, Ammar, Lynne, Burnett, Chris, Haceatrean, Alexei, Gupta, Kusum, Clark, Doug, Venkatraman, Meenakshi, Beigelman, Leonid, Blatt, Lawrence, Lin, Tse-I, Chanda, Sushmita, McClure, Matthew, Fry, John
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
Get full text
Journal Article
Phase Ib study of anti-mesothelin antibody drug conjugate anetumab ravtansine in combination with pegylated liposomal doxorubicin in platinum-resistant ovarian, fallopian tube, or primary peritoneal cancer
Bulat, Iurie, Moore, Kathleen N., Haceatrean, Alexei, Chung, John Woojune, Rajagopalan, Prabhu, Xia, Chenghua, Laurent, Dirk, Childs, Barrett H., Santin, Alessandro
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
Get full text
Journal Article