Clinical advances and ongoing trials of mRNA vaccines for cancer treatment
Lorentzen, Cathrine Lund, Haanen, John B, Met, Özcan, Svane, Inge Marie
Published in The lancet oncology (01.10.2022)
Published in The lancet oncology (01.10.2022)
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Adoptive cellular therapies: the current landscape
Rohaan, Maartje W., Wilgenhof, Sofie, Haanen, John B. A. G.
Published in Virchows Archiv : an international journal of pathology (01.04.2019)
Published in Virchows Archiv : an international journal of pathology (01.04.2019)
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The "cancer immunogram"
Blank, Christian U., Haanen, John B., Ribas, Antoni, Schumacher, Ton N.
Published in Science (American Association for the Advancement of Science) (06.05.2016)
Published in Science (American Association for the Advancement of Science) (06.05.2016)
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Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial
Voorwerk, Leonie, Slagter, Maarten, Horlings, Hugo M., Sikorska, Karolina, van de Vijver, Koen K., de Maaker, Michiel, Nederlof, Iris, Kluin, Roelof J. C., Warren, Sarah, Ong, SuFey, Wiersma, Terry G., Russell, Nicola S., Lalezari, Ferry, Schouten, Philip C., Bakker, Noor A. M., Ketelaars, Steven L. C., Peters, Dennis, Lange, Charlotte A. H., van Werkhoven, Erik, van Tinteren, Harm, Mandjes, Ingrid A. M., Kemper, Inge, Onderwater, Suzanne, Chalabi, Myriam, Wilgenhof, Sofie, Haanen, John B. A. G., Salgado, Roberto, de Visser, Karin E., Sonke, Gabe S., Wessels, Lodewyk F. A., Linn, Sabine C., Schumacher, Ton N., Blank, Christian U., Kok, Marleen
Published in Nature medicine (01.06.2019)
Published in Nature medicine (01.06.2019)
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Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers
Scheper, Wouter, Kelderman, Sander, Fanchi, Lorenzo F., Linnemann, Carsten, Bendle, Gavin, de Rooij, Marije A. J., Hirt, Christian, Mezzadra, Riccardo, Slagter, Maarten, Dijkstra, Krijn, Kluin, Roelof J. C., Snaebjornsson, Petur, Milne, Katy, Nelson, Brad H., Zijlmans, Henry, Kenter, Gemma, Voest, Emile E., Haanen, John B. A. G., Schumacher, Ton N.
Published in Nature medicine (01.01.2019)
Published in Nature medicine (01.01.2019)
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Avelumab plus axitinib versus sunitinib in advanced renal cell carcinoma: biomarker analysis of the phase 3 JAVELIN Renal 101 trial
Motzer, Robert J., Robbins, Paul B., Powles, Thomas, Albiges, Laurence, Haanen, John B., Larkin, James, Mu, Xinmeng Jasmine, Ching, Keith A., Uemura, Motohide, Pal, Sumanta K., Alekseev, Boris, Gravis, Gwenaelle, Campbell, Matthew T., Penkov, Konstantin, Lee, Jae Lyun, Hariharan, Subramanian, Wang, Xiao, Zhang, Weidong, Wang, Jing, Chudnovsky, Aleksander, di Pietro, Alessandra, Donahue, Amber C., Choueiri, Toni K.
Published in Nature medicine (01.11.2020)
Published in Nature medicine (01.11.2020)
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Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers
Chalabi, Myriam, Fanchi, Lorenzo F., Dijkstra, Krijn K., Van den Berg, José G., Aalbers, Arend G., Sikorska, Karolina, Lopez-Yurda, Marta, Grootscholten, Cecile, Beets, Geerard L., Snaebjornsson, Petur, Maas, Monique, Mertz, Marjolijn, Veninga, Vivien, Bounova, Gergana, Broeks, Annegien, Beets-Tan, Regina G., de Wijkerslooth, Thomas R., van Lent, Anja U., Marsman, Hendrik A., Nuijten, Elvira, Kok, Niels F., Kuiper, Maria, Verbeek, Wieke H., Kok, Marleen, Van Leerdam, Monique E., Schumacher, Ton N., Voest, Emile E., Haanen, John B.
Published in Nature medicine (01.04.2020)
Published in Nature medicine (01.04.2020)
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Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma
Vos, Joris L., Elbers, Joris B. W., Krijgsman, Oscar, Traets, Joleen J. H., Qiao, Xiaohang, van der Leun, Anne M., Lubeck, Yoni, Seignette, Iris M., Smit, Laura A., Willems, Stefan M., van den Brekel, Michiel W. M., Dirven, Richard, Baris Karakullukcu, M., Karssemakers, Luc, Klop, W. Martin C., Lohuis, Peter J. F. M., Schreuder, Willem H., Smeele, Ludi E., van der Velden, Lilly-Ann, Bing Tan, I., Onderwater, Suzanne, Jasperse, Bas, Vogel, Wouter V., Al-Mamgani, Abrahim, Keijser, Astrid, van der Noort, Vincent, Broeks, Annegien, Hooijberg, Erik, Peeper, Daniel S., Schumacher, Ton N., Blank, Christian U., de Boer, Jan Paul, Haanen, John B. A. G., Zuur, Charlotte L.
Published in Nature communications (22.12.2021)
Published in Nature communications (22.12.2021)
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Adoptive transfer of tumor-infiltrating lymphocytes in melanoma: a viable treatment option
Rohaan, Maartje W, van den Berg, Joost H, Kvistborg, Pia, Haanen, John B A G
Published in Journal for Immunotherapy of Cancer (03.10.2018)
Published in Journal for Immunotherapy of Cancer (03.10.2018)
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Book Review
Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial
Long, Georgina V, MD, Stroyakovskiy, Daniil, MD, Gogas, Helen, MD, Levchenko, Evgeny, MD, de Braud, Filippo, MD, Larkin, James, FRCP, Garbe, Claus, Prof, Jouary, Thomas, MD, Hauschild, Axel, Prof, Grob, Jean-Jacques, Prof, Chiarion-Sileni, Vanna, MD, Lebbe, Celeste, Prof, Mandalà, Mario, MD, Millward, Michael, Prof, Arance, Ana, MD, Bondarenko, Igor, Prof, Haanen, John B A G, Prof, Hansson, Johan, Prof, Utikal, Jochen, Prof, Ferraresi, Virginia, MD, Kovalenko, Nadezhda, Prof, Mohr, Peter, MD, Probachai, Volodymr, MD, Schadendorf, Dirk, Prof, Nathan, Paul, MD, Robert, Caroline, MD, Ribas, Antoni, Prof, DeMarini, Douglas J, PhD, Irani, Jhangir G, MA, Swann, Suzanne, PhD, Legos, Jeffrey J, PhD, Jin, Fan, MD, Mookerjee, Bijoyesh, MD, Flaherty, Keith, MD
Published in The Lancet (British edition) (01.08.2015)
Published in The Lancet (British edition) (01.08.2015)
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Phase III Randomized Clinical Trial Comparing Tremelimumab With Standard-of-Care Chemotherapy in Patients With Advanced Melanoma
RIBAS, Antoni, KEFFORD, Richard, LORIGAN, Paul, KENDRA, Kari L, MAIO, Michele, TREFZER, Uwe, SMYLIE, Michael, MCARTHUR, Grant A, DRENO, Brigitte, NATHAN, Paul D, MACKIEWICZ, Jacek, KIRKWOOD, John M, MARSHALL, Margaret A, GOMEZ-NAVARRO, Jesus, BO HUANG, PAVLOV, Dmitri, HAUSCHILD, Axel, PUNT, Cornelis J. A, HAANEN, John B, MARMOL, Maribel, GARBE, Claus, GOGAS, Helen, SCHACHTER, Jacob, LINETTE, Gerald
Published in Journal of clinical oncology (10.02.2013)
Published in Journal of clinical oncology (10.02.2013)
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Cancer immunotherapy – revisited
Punt, Cornelis J. A, Lesterhuis, W. Joost, Haanen, John B. A. G
Published in Nature reviews. Drug discovery (01.08.2011)
Published in Nature reviews. Drug discovery (01.08.2011)
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Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy
Logtenberg, Meike E. W., Jansen, J. H. Marco, Raaben, Matthijs, Toebes, Mireille, Franke, Katka, Brandsma, Arianne M., Matlung, Hanke L., Fauster, Astrid, Gomez-Eerland, Raquel, Bakker, Noor A. M., van der Schot, Simone, Marijt, Koen A., Verdoes, Martijn, Haanen, John B. A. G., van den Berg, Joost H., Neefjes, Jacques, van den Berg, Timo K., Brummelkamp, Thijn R., Leusen, Jeanette H. W., Scheeren, Ferenc A., Schumacher, Ton N.
Published in Nature medicine (01.04.2019)
Published in Nature medicine (01.04.2019)
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Tissue-resident memory CD8⁺ T cells continuously patrol skin epithelia to quickly recognize local antigen
Ariotti, Silvia, Beltman, Joost B, Chodaczek, Grzegorz, Hoekstra, Mirjam E, van Beek, Anna E, Gomez-Eerland, Raquel, Ritsma, Laila, van Rheenen, Jacco, Marée, Athanasius F. M, Zal, Tomasz, de Boer, Rob J, Haanen, John B. A. G, Schumacher, Ton N
Published in Proceedings of the National Academy of Sciences - PNAS (27.11.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (27.11.2012)
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Identification of patient-specific CD4+ and CD8+ T cell neoantigens through HLA-unbiased genetic screens
Cattaneo, Chiara M., Battaglia, Thomas, Urbanus, Jos, Moravec, Ziva, Voogd, Rhianne, de Groot, Rosa, Hartemink, Koen J., Haanen, John B. A. G., Voest, Emile E., Schumacher, Ton N., Scheper, Wouter
Published in Nature biotechnology (01.06.2023)
Published in Nature biotechnology (01.06.2023)
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Sunitinib pretreatment improves tumor-infiltrating lymphocyte expansion by reduction in intratumoral content of myeloid-derived suppressor cells in human renal cell carcinoma
Guislain, Aurelie, Gadiot, Jules, Kaiser, Andrew, Jordanova, Ekaterina S., Broeks, Annegien, Sanders, Joyce, van Boven, Hester, de Gruijl, Tanja D., Haanen, John B. A. G., Bex, Axel, Blank, Christian U.
Published in Cancer Immunology, Immunotherapy (01.10.2015)
Published in Cancer Immunology, Immunotherapy (01.10.2015)
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COVID-19 vaccination: the VOICE for patients with cancer
van der Veldt, Astrid A. M., Oosting, Sjoukje F., Dingemans, Anne-Marie C., Fehrmann, Rudolf S. N., GeurtsvanKessel, Corine, Jalving, Mathilde, Rimmelzwaan, Guus F., Kvistborg, Pia, Blank, Christian U., Smit, Egbert F., Lemmens, Valery E. E. P., Hiltermann, T. Jeroen N., Koopmans, Marion P. G., Huckriede, Anke L. W., Rots, Nynke Y., van Els, Cecile A. C. M., van Baarle, Debbie, Haanen, John B. A. G., de Vries, Elisabeth G. E.
Published in Nature medicine (01.04.2021)
Published in Nature medicine (01.04.2021)
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Neoadjuvant atezolizumab plus chemotherapy in gastric and gastroesophageal junction adenocarcinoma: the phase 2 PANDA trial
Verschoor, Yara L., van de Haar, Joris, van den Berg, José G., van Sandick, Johanna W., Kodach, Liudmila L., van Dieren, Jolanda M., Balduzzi, Sara, Grootscholten, Cecile, IJsselsteijn, Marieke E., Veenhof, Alexander A. F. A., Hartemink, Koen J., Vollebergh, Marieke A., Jurdi, Adham, Sharma, Shruti, Spickard, Erik, Owers, Emilia C., Bartels-Rutten, Annemarieke, den Hartog, Peggy, de Miranda, Noel F. C. C., van Leerdam, Monique E., Haanen, John B. A. G., Schumacher, Ton N., Voest, Emile E., Chalabi, Myriam
Published in Nature medicine (01.02.2024)
Published in Nature medicine (01.02.2024)
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[18F]FDG-PET accurately identifies pathological response early upon neoadjuvant immune checkpoint blockade in head and neck squamous cell carcinoma
Vos, Joris L., Zuur, Charlotte L., Smit, Laura A., de Boer, Jan Paul, Al-Mamgani, Abrahim, van den Brekel, Michiel W. M., Haanen, John B. A. G., Vogel, Wouter V.
Published in European journal of nuclear medicine and molecular imaging (01.05.2022)
Published in European journal of nuclear medicine and molecular imaging (01.05.2022)
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