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Okarmus, Justyna, Bogetofte, Helle, Schmidt, Sissel Ida, Ryding, Matias, García-López, Silvia, Ryan, Brent James, Martínez-Serrano, Alberto, Hyttel, Poul, Meyer, Morten
Published in Scientific reports (24.06.2020)
Published in Scientific reports (24.06.2020)
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Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation
Ochalek, Anna, Mihalik, Balázs, Avci, Hasan X, Chandrasekaran, Abinaya, Téglási, Annamária, Bock, István, Giudice, Maria Lo, Táncos, Zsuzsanna, Molnár, Kinga, László, Lajos, Nielsen, Jørgen E, Holst, Bjørn, Freude, Kristine, Hyttel, Poul, Kobolák, Julianna, Dinnyés, András
Published in Alzheimer's research & therapy (01.12.2017)
Published in Alzheimer's research & therapy (01.12.2017)
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The transcriptomic landscape of neurons carrying PSEN1 mutations reveals changes in extracellular matrix components and non-coding gene expression
Corsi, Giulia I., Gadekar, Veerendra P., Haukedal, Henriette, Doncheva, Nadezhda T., Anthon, Christian, Ambardar, Sheetal, Palakodeti, Dasaradhi, Hyttel, Poul, Freude, Kristine, Seemann, Stefan E., Gorodkin, Jan
Published in Neurobiology of disease (01.03.2023)
Published in Neurobiology of disease (01.03.2023)
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Application of multi-omics data integration and machine learning approaches to identify epigenetic and transcriptomic differences between in vitro and in vivo produced bovine embryos
Rabaglino, Maria B, O'Doherty, Alan, Bojsen-Møller Secher, Jan, Lonergan, Patrick, Hyttel, Poul, Fair, Trudee, Kadarmideen, Haja N
Published in PloS one (24.05.2021)
Published in PloS one (24.05.2021)
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Glutamate-glutamine homeostasis is perturbed in neurons and astrocytes derived from patient iPSC models of frontotemporal dementia
Aldana, Blanca I, Zhang, Yu, Jensen, Pia, Chandrasekaran, Abinaya, Christensen, Sofie K, Nielsen, Troels T, Nielsen, Jørgen E, Hyttel, Poul, Larsen, Martin R, Waagepetersen, Helle S, Freude, Kristine K
Published in Molecular brain (14.09.2020)
Published in Molecular brain (14.09.2020)
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FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms
Stoklund Dittlau, Katarina, Terrie, Lisanne, Baatsen, Pieter, Kerstens, Axelle, De Swert, Lim, Janky, Rekin's, Corthout, Nikky, Masrori, Pegah, Van Damme, Philip, Hyttel, Poul, Meyer, Morten, Thorrez, Lieven, Freude, Kristine, Van Den Bosch, Ludo
Published in Molecular neurodegeneration (18.01.2023)
Published in Molecular neurodegeneration (18.01.2023)
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Transient p53 Suppression Increases Reprogramming of Human Fibroblasts without Affecting Apoptosis and DNA Damage
Rasmussen, Mikkel A., Holst, Bjørn, Tümer, Zeynep, Johnsen, Mads G., Zhou, Shuling, Stummann, Tina C., Hyttel, Poul, Clausen, Christian
Published in Stem cell reports (09.09.2014)
Published in Stem cell reports (09.09.2014)
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Golgi fragmentation - One of the earliest organelle phenotypes in Alzheimer's disease neurons
Haukedal, Henriette, Corsi, Giulia I, Gadekar, Veerendra P, Doncheva, Nadezhda T, Kedia, Shekhar, de Haan, Noortje, Chandrasekaran, Abinaya, Jensen, Pia, Schiønning, Pernille, Vallin, Sarah, Marlet, Frederik Ravnkilde, Poon, Anna, Pires, Carlota, Agha, Fawzi Khoder, Wandall, Hans H, Cirera, Susanna, Simonsen, Anja Hviid, Nielsen, Troels Tolstrup, Nielsen, Jørgen Erik, Hyttel, Poul, Muddashetty, Ravi, Aldana, Blanca I, Gorodkin, Jan, Nair, Deepak, Meyer, Morten, Larsen, Martin Røssel, Freude, Kristine
Published in Frontiers in neuroscience (16.02.2023)
Published in Frontiers in neuroscience (16.02.2023)
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Alpha7 nicotinic acetylcholine receptors and neural network synaptic transmission in human induced pluripotent stem cell-derived neurons
Larsen, Hjalte M., Hansen, Susanne K., Mikkelsen, Jens D., Hyttel, Poul, Stummann, Tina C.
Published in Stem cell research (01.12.2019)
Published in Stem cell research (01.12.2019)
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Identification of potential biomarkers in donor cows for in vitro embryo production by granulosa cell transcriptomics
Mazzoni, Gianluca, Salleh, Suraya M, Freude, Kristine, Pedersen, Hanne S, Stroebech, Lotte, Callesen, Henrik, Hyttel, Poul, Kadarmideen, Haja N
Published in PloS one (12.04.2017)
Published in PloS one (12.04.2017)
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Oocyte morphology and transcriptional silencing in relation to chromatin remodeling during the final phases of bovine oocyte growth
Lodde, Valentina, Modina, Silvia, Maddox-Hyttel, Poul, Franciosi, Federica, Lauria, Antonio, Luciano, Alberto M.
Published in Molecular reproduction and development (01.05.2008)
Published in Molecular reproduction and development (01.05.2008)
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Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B
Zhang, Yu, Schmid, Benjamin, Nikolaisen, Nanett K., Rasmussen, Mikkel A., Aldana, Blanca I., Agger, Mikkel, Calloe, Kirstine, Stummann, Tina C., Larsen, Hjalte M., Nielsen, Troels T., Huang, Jinrong, Xu, Fengping, Liu, Xin, Bolund, Lars, Meyer, Morten, Bak, Lasse K., Waagepetersen, Helle S., Luo, Yonglun, Nielsen, Jørgen E., Holst, Bjørn, Clausen, Christian, Hyttel, Poul, Freude, Kristine K.
Published in Stem cell reports (14.03.2017)
Published in Stem cell reports (14.03.2017)
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Neurosphere Based Differentiation of Human iPSC Improves Astrocyte Differentiation
Hyttel, Poul, Dinnyés, András, Freude, Kristine K., Avci, Hasan X., Rasmussen, Mikkel, Chandrasekaran, Abinaya, Nemes, Csilla, Varga, Eszter, Kobolák, Julianna, Ochalek, Anna, Szczesna, Karolina, Zhou, Shuling, Cirera, Susanna
Published in Stem cells international (01.01.2016)
Published in Stem cells international (01.01.2016)
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Cellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism who carries a novel variation (p.Q811R) in the POLG1 gene
Chumarina, Margarita, Russ, Kaspar, Azevedo, Carla, Heuer, Andreas, Pihl, Maria, Collin, Anna, Frostner, Eleonor Åsander, Elmer, Eskil, Hyttel, Poul, Cappelletti, Graziella, Zini, Michela, Goldwurm, Stefano, Roybon, Laurent
Published in Acta neuropathologica communications (16.12.2019)
Published in Acta neuropathologica communications (16.12.2019)
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DNA methylation in porcine preimplantation embryos developed in vivo and produced by in vitro fertilization, parthenogenetic activation and somatic cell nuclear transfer
Deshmukh, Rahul S., Østrup, Olga, Østrup, Esben, Vejlsted, Morten, Niemann, Heiner, Lucas-Hahn, Andrea, Petersen, Bjoern, Li, Juan, Callesen, Henrik, Hyttel, Poul
Published in Epigenetics (01.02.2011)
Published in Epigenetics (01.02.2011)
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Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1
Pires, Carlota, Schmid, Benjamin, Petræus, Carina, Poon, Anna, Nimsanor, Natakarn, Nielsen, Troels T., Waldemar, Gunhild, Hjermind, Lena E., Nielsen, Jørgen E., Hyttel, Poul, Freude, Kristine K.
Published in Stem cell research (01.09.2016)
Published in Stem cell research (01.09.2016)
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Development of the Entorhinal Cortex Occurs via Parallel Lamination During Neurogenesis
Liu, Yong, Bergmann, Tobias, Mori, Yuki, Peralvo Vidal, Juan Miguel, Pihl, Maria, Vasistha, Navneet A., Thomsen, Preben Dybdahl, Seemann, Stefan E., Gorodkin, Jan, Hyttel, Poul, Khodosevich, Konstantin, Witter, Menno P., Hall, Vanessa Jane
Published in Frontiers in neuroanatomy (05.05.2021)
Published in Frontiers in neuroanatomy (05.05.2021)
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