Synthesis and biological evaluation of substituted benzoxazoles as inhibitors of mPGES-1: Use of a conformation-based hypothesis to facilitate compound design
Walker, Daniel P., Arhancet, Graciela B., Lu, Hwang-Fun, Heasley, Steven E., Metz, Sue, Kablaoui, Natasha M., Franco, Francisco M., Hanau, Cathleen E., Scholten, Jeffrey A., Springer, John R., Fobian, Yvette M., Carter, Jeffrey S., Xing, Li, Yang, Shengtian, Shaffer, Alexander F., Jerome, Gina M., Baratta, Michael T., Moore, William M., Vazquez, Michael L.
Published in Bioorganic & medicinal chemistry letters (15.02.2013)
Published in Bioorganic & medicinal chemistry letters (15.02.2013)
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Selective peptidic and peptidomimetic inhibitors of Candida albicans myristoylCoA: Protein N-myristoyltransferase: A new approach to antifungal therapy
Sikorski, James A., Devadas, Balekudru, Zupec, Mark E., Freeman, Sandra K., Brown, David L., Lu, Hwang-Fun, Nagarajan, Srinivasan, Mehta, Pramod P., Wade, Arlene C., Kishore, Nandini S., Bryant, Martin L., Getman, Daniel P., McWherter, Charles A., Gordon, Jeffrey I.
Published in Biopolymers (1997)
Published in Biopolymers (1997)
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Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease
Nagarajan, Srinivasan R, De Crescenzo, Gary A, Getman, Daniel P, Lu, Hwang-Fun, Sikorski, James A, Walker, Jeffrey L, McDonald, Joseph J, Houseman, Kathryn A, Kocan, Geralyn P, Kishore, Nandini, Mehta, Pramod P, Funkes-Shippy, Christie L, Blystone, Lisa
Published in Bioorganic & medicinal chemistry (03.11.2003)
Published in Bioorganic & medicinal chemistry (03.11.2003)
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R-isomers of Arg-Gly-Asp (RGD) mimics as potent αvβ3 inhibitors
NAGARAJAN, Srinivasan R, DEVADAS, Balekudru, LANTZ, Melissa K, JUN ZHU, GREEN, Nawasa F, RUSSELL, Mark A, LANDIS, Bryan H, MILLER, Lawrence M, MEYER, Debra M, DUFFIN, Tiffany D, ENGLEMAN, V. Wayne, FINN, Mary B, MALECHA, James W, FREEMAN, Sandra K, GRIGGS, David W, WILLIAMS, Melanie L, NICKOLS, Maureen A, PEGG, Jodi A, SHANNON, Kristen E, STEININGER, Christina, WESTLIN, Marisa M, NICKOLS, G. Alan, KEENE, Jeffery L, LU, Hwang-Fun, RUMINSKI, Peter G, RICO, Joseph G, ROGERS, Thomas E, MARRUFO, Laura D, COLLINS, Joe T, KLEINE, H. Peter
Published in Bioorganic & medicinal chemistry (01.06.2007)
Published in Bioorganic & medicinal chemistry (01.06.2007)
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Discovery of + (2 -{4 -[2 -(5,6,7,8 -tetrahydro -1,8 -naphthyridin -2-yl )ethoxy ]phenyl} -cyclopropyl )acetic acid as potent and selective αvβ3 inhibitor : Design, synthesis, and optimization
NAGARAJAN, Srinivasan R, LU, Hwang-Fun, KEENE, Jeffery L, DUFFIN, Tiffany, ENGLEMAN, V. Wayne, FINN, Mary B, FREEMAN, Sandra K, KLOVER, Jon A, NICKOLS, G. Alan, NICKOLS, Maureen A, SHANNON, Kristen E, STEININGER, Christina A, GASIECKI, Alan F, WESTLIN, William F, WESTLIN, Marisa M, WILLIAMS, Melanie L, KHANNA, Ish K, PARIKH, Mihir D, DESAI, Bipinchandra N, ROGERS, Thomas E, CLARE, Michael, CHEN, Barbara B, RUSSELL, Mark A
Published in Bioorganic & medicinal chemistry (15.05.2007)
Published in Bioorganic & medicinal chemistry (15.05.2007)
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Replacements for lysine in l-seryl- l-lysyl dipeptide amide inhibitors of candida albicans myristoyl-CoA:protein N-myristoyltransferase
Brown, David L., Devadas, Balekudru, Lu, Hwang-Fun, Nagarajan, Srinivasan, Zupec, Mark E., Freeman, Sandra K., McWherter, Charles A., Getman, Daniel P., Sikorski, James A.
Published in Bioorganic & medicinal chemistry letters (04.02.1997)
Published in Bioorganic & medicinal chemistry letters (04.02.1997)
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Journal Article
Conformationally Constrained [p-(ω-Aminoalkyl)phenacetyl]-l-seryl-l-lysyl Dipeptide Amides as Potent Peptidomimetic Inhibitors of Candida albicans and Human Myristoyl-CoA:Protein N-Myristoyl Transferase
Nagarajan, Srinivasan R, Devadas, Balekudru, Zupec, Mark E, Freeman, Sandra K, Brown, David L, Lu, Hwang-Fun, Mehta, Pramod P, Kishore, Nandini S, McWherter, Charles A, Getman, Daniel P, Gordon, Jeffrey I, Sikorski, James A
Published in Journal of medicinal chemistry (09.05.1997)
Published in Journal of medicinal chemistry (09.05.1997)
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A Practical Synthesis of [(1S,3S)-3-Aminocyclohexyl]methanol and 2-[(1S,3S)-3-Aminocyclohexyl]propan-2-ol, Useful Intermediates for the Preparation of Novel mPGES-1 Inhibitors
Walker, Daniel P., Heasley, Steven E., MacInnes, Allison, Anjeh, Tizah, Lu, Hwang-Fun, Fobian, Yvette M., Collins, Joe T., Vazquez, Michael L., Mao, Michael K.
Published in Synlett (01.12.2011)
Published in Synlett (01.12.2011)
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Journal Article
Discovery of +(2-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acid as potent and selective alphavbeta3 inhibitor: design, synthesis, and optimization
Nagarajan, Srinivasan R, Lu, Hwang-Fun, Gasiecki, Alan F, Khanna, Ish K, Parikh, Mihir D, Desai, Bipinchandra N, Rogers, Thomas E, Clare, Michael, Chen, Barbara B, Russell, Mark A, Keene, Jeffery L, Duffin, Tiffany, Engleman, V Wayne, Finn, Mary B, Freeman, Sandra K, Klover, Jon A, Nickols, G Alan, Nickols, Maureen A, Shannon, Kristen E, Steininger, Christina A, Westlin, William F, Westlin, Marisa M, Williams, Melanie L
Published in Bioorganic & medicinal chemistry (15.05.2007)
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Published in Bioorganic & medicinal chemistry (15.05.2007)
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Discovery of +(2-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acid as potent and selective α vβ 3 inhibitor: Design, synthesis, and optimization
Nagarajan, Srinivasan R., Lu, Hwang-Fun, Gasiecki, Alan F., Khanna, Ish K., Parikh, Mihir D., Desai, Bipinchandra N., Rogers, Thomas E., Clare, Michael, Chen, Barbara B., Russell, Mark A., Keene, Jeffery L., Duffin, Tiffany, Engleman, V. Wayne, Finn, Mary B., Freeman, Sandra K., Klover, Jon A., Nickols, G. Alan, Nickols, Maureen A., Shannon, Kristen E., Steininger, Christina A., Westlin, William F., Westlin, Marisa M., Williams, Melanie L.
Published in Bioorganic & medicinal chemistry (2007)
Published in Bioorganic & medicinal chemistry (2007)
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Journal Article
R-isomers of Arg-Gly-Asp (RGD) mimics as potent alphavbeta3 inhibitors
Nagarajan, Srinivasan R, Devadas, Balekudru, Malecha, James W, Lu, Hwang-Fun, Ruminski, Peter G, Rico, Joseph G, Rogers, Thomas E, Marrufo, Laura D, Collins, Joe T, Kleine, H Peter, Lantz, Melissa K, Zhu, Jun, Green, Nawasa F, Russell, Mark A, Landis, Bryan H, Miller, Lawrence M, Meyer, Debra M, Duffin, Tiffany D, Engleman, V Wayne, Finn, Mary B, Freeman, Sandra K, Griggs, David W, Williams, Melanie L, Nickols, Maureen A, Pegg, Jodi A, Shannon, Kristen E, Steininger, Christina, Westlin, Marisa M, Nickols, G Alan, Keene, Jeffery L
Published in Bioorganic & medicinal chemistry (01.06.2007)
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Published in Bioorganic & medicinal chemistry (01.06.2007)
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R-Isomers of Arg-Gly-Asp (RGD) mimics as potent α vβ 3 inhibitors
Nagarajan, Srinivasan R., Devadas, Balekudru, Malecha, James W., Lu, Hwang-Fun, Ruminski, Peter G., Rico, Joseph G., Rogers, Thomas E., Marrufo, Laura D., Collins, Joe T., Kleine, H. Peter, Lantz, Melissa K., Zhu, Jun, Green, Nawasa F., Russell, Mark A., Landis, Bryan H., Miller, Lawrence M., Meyer, Debra M., Duffin, Tiffany D., Engleman, V. Wayne, Finn, Mary B., Freeman, Sandra K., Griggs, David W., Williams, Melanie L., Nickols, Maureen A., Pegg, Jodi A., Shannon, Kristen E., Steininger, Christina, Westlin, Marisa M., Nickols, G. Alan, Keene, Jeffery L.
Published in Bioorganic & medicinal chemistry (2007)
Published in Bioorganic & medicinal chemistry (2007)
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Design and Synthesis of Novel Imidazole-Substituted Dipeptide Amides as Potent and Selective Inhibitors of Candida albicans MyristoylCoA:Protein N-Myristoyltransferase and Identification of Related Tripeptide Inhibitors with Mechanism-Based Antifungal Activity
Devadas, Balekudru, Freeman, Sandra K, Zupec, Mark E, Lu, Hwang-Fun, Nagarajan, Srinivasan R, Kishore, Nandini S, Lodge, Jennifer K, Kuneman, David W, McWherter, Charles A, Vinjamoori, Dutt V, Getman, Daniel P, Gordon, Jeffrey I, Sikorski, James A
Published in Journal of medicinal chemistry (01.08.1997)
Published in Journal of medicinal chemistry (01.08.1997)
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Structure-activity studies of fluoroalkyl-substituted gamma-butyrolactone and gamma-thiobutyrolactone modulators of GABA(A) receptor function
Canney, D J, Lu, H F, McKeon, A C, Yoon, K W, Xu, K, Holland, K D, Rothman, S M, Ferrendelli, J A, Covey, D F
Published in Bioorganic & medicinal chemistry (01.01.1998)
Published in Bioorganic & medicinal chemistry (01.01.1998)
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Journal Article
Structure-activity studies of fluoroaljyl-substituted γ-butyrolactone and γ-thiobutyrolactone modulators of GABAA receptor function
Canney, Daniel J., Lu, Hwang-Fun, McKeon, Ann C., Yoon, Kong-Woo, Xu, Kun, Holland, Katherine D., Rothman, Steven M., Ferrendelli, James A., Covey, Douglas F.
Published in Bioorganic & medicinal chemistry (01.01.1998)
Published in Bioorganic & medicinal chemistry (01.01.1998)
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Journal Article
Structure-activity studies of fluoroaljyl-substituted γ-butyrolactone and γ-thiobutyrolactone modulators of GABA A receptor function
Canney, Daniel J., Lu, Hwang-Fun, McKeon, Ann C., Yoon, Kong-Woo, Xu, Kun, Holland, Katherine D., Rothman, Steven M., Ferrendelli, James A., Covey, Douglas F.
Published in Bioorganic & medicinal chemistry (1998)
Published in Bioorganic & medicinal chemistry (1998)
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Cycloalkyl alkanoic acids as integrin receptor antagonists
Clare, Michael, Khanna, Ish Kumar, Gasiecki, Alan, Rogers, Thomas, Chen, Barbara, Lu, Hwang-Fun
Year of Publication 23.12.2004
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Year of Publication 23.12.2004
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