Current advances of tubulin inhibitors as dual acting small molecules for cancer therapy
Arnst, Kinsie E, Banerjee, Souvik, Chen, Hao, Deng, Shanshan, Hwang, Dong‐Jin, Li, Wei, Miller, Duane D
Published in Medicinal research reviews (01.07.2019)
Published in Medicinal research reviews (01.07.2019)
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A Potent, Metabolically Stable Tubulin Inhibitor Targets the Colchicine Binding Site and Overcomes Taxane Resistance
Arnst, Kinsie E, Wang, Yuxi, Hwang, Dong-Jin, Xue, Yi, Costello, Terry, Hamilton, David, Chen, Qiang, Yang, Jinliang, Park, Frank, Dalton, James T, Miller, Duane D, Li, Wei
Published in Cancer research (Chicago, Ill.) (01.01.2018)
Published in Cancer research (Chicago, Ill.) (01.01.2018)
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Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer
Ponnusamy, Suriyan, Coss, Christopher C, Thiyagarajan, Thirumagal, Watts, Kate, Hwang, Dong-Jin, He, Yali, Selth, Luke A, McEwan, Iain J, Duke, Charles B, Pagadala, Jayaprakash, Singh, Geetika, Wake, Robert W, Ledbetter, Christopher, Tilley, Wayne D, Moldoveanu, Tudor, Dalton, James T, Miller, Duane D, Narayanan, Ramesh
Published in Cancer research (Chicago, Ill.) (15.11.2017)
Published in Cancer research (Chicago, Ill.) (15.11.2017)
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An Overview of Next-Generation Androgen Receptor-Targeted Therapeutics in Development for the Treatment of Prostate Cancer
Mohler, Michael L, Sikdar, Arunima, Ponnusamy, Suriyan, Hwang, Dong-Jin, He, Yali, Miller, Duane D, Narayanan, Ramesh
Published in International journal of molecular sciences (20.02.2021)
Published in International journal of molecular sciences (20.02.2021)
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Journal Article
Computationally identified novel agonists for GPRC6A
Pi, Min, Kapoor, Karan, Ye, Ruisong, Hwang, Dong-Jin, Miller, Duane D, Smith, Jeremy C, Baudry, Jerome, Quarles, L Darryl
Published in PloS one (23.04.2018)
Published in PloS one (23.04.2018)
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Nonsteroidal Selective Androgen Receptor Modulators (SARMs): Dissociating the Anabolic and Androgenic Activities of the Androgen Receptor for Therapeutic Benefit
Mohler, Michael L, Bohl, Casey E, Jones, Amanda, Coss, Christopher C, Narayanan, Ramesh, He, Yali, Hwang, Dong Jin, Dalton, James T, Miller, Duane D
Published in Journal of medicinal chemistry (25.06.2009)
Published in Journal of medicinal chemistry (25.06.2009)
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Identification of a targetable JAK-STAT enriched androgen receptor and androgen receptor splice variant positive triple-negative breast cancer subtype
Asemota, Sarah, Effah, Wendy, Young, Kirsten L., Holt, Jeremiah, Cripe, Linnea, Ponnusamy, Suriyan, Thiyagarajan, Thirumagal, Hwang, Dong-Jin, He, Yali, Mcnamara, Keely, Johnson, Daniel, Wang, Yinan, Grimes, Brandy, Khosrosereshki, Yekta, Hollingsworth, T.J., Fleming, Martin D., Pritchard, Frances E., Hendrix, Ashley, Khan, Farhan, Fan, Meiyun, Makowski, Liza, Yin, Zheng, Sasano, Hironobu, Hayes, D. Neil, Pfeffer, Lawrence M., Miller, Duane D., Narayanan, Ramesh
Published in Cell reports (Cambridge) (26.12.2023)
Published in Cell reports (Cambridge) (26.12.2023)
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Anthrax toxin lethal factor domain 3 is highly mobile and responsive to ligand binding
Maize, Kimberly M., Kurbanov, Elbek K., De La Mora-Rey, Teresa, Geders, Todd W., Hwang, Dong-Jin, Walters, Michael A., Johnson, Rodney L., Amin, Elizabeth A., Finzel, Barry C.
Published in Acta crystallographica. Section D, Biological crystallography. (01.11.2014)
Published in Acta crystallographica. Section D, Biological crystallography. (01.11.2014)
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Exploration and Biological Evaluation of Basic Heteromonocyclic Propanamide Derivatives as SARDs for the Treatment of Enzalutamide-Resistant Prostate Cancer
He, Yali, Hwang, Dong-Jin, Ponnusamy, Suriyan, Thiyagarajan, Thirumagal, Mohler, Michael L, Narayanan, Ramesh, Miller, Duane D
Published in Journal of medicinal chemistry (12.08.2021)
Published in Journal of medicinal chemistry (12.08.2021)
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The Para Substituent of S-3-(Phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamides Is a Major Structural Determinant of in Vivo Disposition and Activity of Selective Androgen Receptor Modulators
Kim, Juhyun, Wu, Di, Hwang, Dong Jin, Miller, Duane D, Dalton, James T
Published in The Journal of pharmacology and experimental therapeutics (01.10.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2005)
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Metabolism-Guided Selective Androgen Receptor Antagonists: Design, Synthesis, and Biological Evaluation for Activity against Enzalutamide-Resistant Prostate Cancer
Hwang, Dong-Jin, He, Yali, Ponnusamy, Suriyan, Thiyagarajan, Thirumagal, Mohler, Michael L., Narayanan, Ramesh, Miller, Duane D.
Published in Journal of medicinal chemistry (09.03.2023)
Published in Journal of medicinal chemistry (09.03.2023)
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Pyrazol-1-yl-propanamides as SARD and Pan-Antagonists for the Treatment of Enzalutamide-Resistant Prostate Cancer
He, Yali, Hwang, Dong-Jin, Ponnusamy, Suriyan, Thiyagarajan, Thirumagal, Mohler, Michael L, Narayanan, Ramesh, Miller, Duane D
Published in Journal of medicinal chemistry (12.11.2020)
Published in Journal of medicinal chemistry (12.11.2020)
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New Generation of Selective Androgen Receptor Degraders: Our Initial Design, Synthesis, and Biological Evaluation of New Compounds with Enzalutamide-Resistant Prostate Cancer Activity
Hwang, Dong-Jin, He, Yali, Ponnusamy, Suriyan, Mohler, Michael L, Thiyagarajan, Thirumagal, McEwan, Iain J, Narayanan, Ramesh, Miller, Duane D
Published in Journal of medicinal chemistry (24.01.2019)
Published in Journal of medicinal chemistry (24.01.2019)
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Structural Optimization of Indole Derivatives Acting at Colchicine Binding Site as Potential Anticancer Agents
Hwang, Dong-Jin, Wang, Jin, Li, Wei, Miller, Duane D
Published in ACS medicinal chemistry letters (10.09.2015)
Published in ACS medicinal chemistry letters (10.09.2015)
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Orally Bioavailable Androgen Receptor Degrader, Potential Next-Generation Therapeutic for Enzalutamide-Resistant Prostate Cancer
Ponnusamy, Suriyan, He, Yali, Hwang, Dong-Jin, Thiyagarajan, Thirumagal, Houtman, Rene, Bocharova, Vera, Sumpter, Bobby G, Fernandez, Elias, Johnson, Daniel, Du, Ziyun, Pfeffer, Lawrence M, Getzenberg, Robert H, McEwan, Iain J, Miller, Duane D, Narayanan, Ramesh
Published in Clinical cancer research (15.11.2019)
Published in Clinical cancer research (15.11.2019)
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Colchicine Binding Site Agent DJ95 Overcomes Drug Resistance and Exhibits Antitumor Efficacy
Arnst, Kinsie E, Wang, Yuxi, Lei, Zi-Ning, Hwang, Dong-Jin, Kumar, Gyanendra, Ma, Dejian, Parke, Deanna N, Chen, Qiang, Yang, Jinliang, White, Stephen W, Seagroves, Tiffany N, Chen, Zhe-Sheng, Miller, Duane D, Li, Wei
Published in Molecular pharmacology (01.07.2019)
Published in Molecular pharmacology (01.07.2019)
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DJ-X-013 reduces LPS-induced inflammation, modulates Th17/ myeloid-derived suppressor cells, and alters NF-κB expression to ameliorate experimental colitis
Mandal, Mousumi, Rakib, Ahmed, Mamun, Md Abdullah Al, Kumar, Santosh, Park, Frank, Hwang, Dong-Jin, Li, Wei, Miller, Duane D., Singh, Udai P.
Published in Biomedicine & pharmacotherapy (01.10.2024)
Published in Biomedicine & pharmacotherapy (01.10.2024)
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