INBRX-120, a CD8α-targeted detuned IL-2 that selectively expands and activates tumoricidal effector cells for safe and durable in vivo responses
Sulzmaier, Florian J, Kern, Nadja, Ahn, Sae Jeong, Polovina, Anya, Ho, Jason, Hussain, Abrahim, Cyprus, Garrett, Macedo, Chelsie, Pandit, Rajay, Crago, William, Rowell, Emily, Timmer, John C, Eckelman, Brendan P
Published in Journal for immunotherapy of cancer (01.01.2023)
Published in Journal for immunotherapy of cancer (01.01.2023)
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Journal Article
722 INBRX-121 is an NKp46-targeted detuned IL-2 with antitumor activity as a monotherapy or in combination with multiple cancer immunotherapy modalities
Sulzmaier, Florian, Kinkead, Heather, Polovina, Anya, Kern, Nadja, Sanabria, Angelica, Macedo, Chelsie, Hussain, Abrahim, Ahn, Sae Jeong, Pandit, Rajay, Crago, William, Timmer, John, Heidt, Analeah, Eckelman, Brendan
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
Preclinical Characterization and Phase I Trial Results of INBRX-109, A Third-Generation, Recombinant, Humanized, Death Receptor 5 Agonist Antibody, in Chondrosarcoma
Subbiah, Vivek, Chawla, Sant P, Conley, Anthony P, Wilky, Breelyn A, Tolcher, Anthony, Lakhani, Nehal J, Berz, David, Andrianov, Vasily, Crago, William, Holcomb, Monica, Hussain, Abrahim, Veldstra, Carson, Kalabus, James, O'Neill, Brianne, Senne, Lane, Rowell, Emily, Heidt, Analeah B, Willis, Katelyn M, Eckelman, Brendan P
Published in Clinical cancer research (15.08.2023)
Published in Clinical cancer research (15.08.2023)
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1077 Development of a molecular targeted cytokine that specifically expands Vgamma9Vdelta2 T cells and potentiates anti-tumor activity
Becklund, Bryan, Robinson, Kaitlyn, Jones, Kyle, Sanabria, Angelica, Torretti, Elisebeth, Eckles, Andrew, Hussain, Abrahim, Sae Jeong Ahn, Pandit, Rajay, Sulzmaier, Florian, Timmer, John, Eckelman, Brendan
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
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Journal Article
Abstract 3513: INBRX-121, a safe and efficacious molecular targeted cytokine that enhances NK cell-mediated tumor killing
Kinkead, Heather, Sulzmaier, Florian J., Polovina, Anya, Kern, Nadja, Sanabria, Angelica, Ho, Jason, Macedo, Chelsie, Henderson, Ryan, Hussain, Abrahim, Pandit, Rajay, Crago, William, Rowell, Emily, Eckelman, Brendan P.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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MULTIVALENT AND MULTISPECIFIC DR5-BINDING FUSION PROTEINS
HUSSAIN ABRAHIM, AMIR S RAZAI, KYLE S JONES, KATELYN M WILLIS, QUINN DEVERAUX, BRENDAN P ECKELMAN, JOHN C TIMMER
Year of Publication 25.03.2021
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Year of Publication 25.03.2021
Patent
다가 및 다중특이적 GITR 결합 융합 단백질
TIMMER JOHN C, RAZAI AMIR S, HUSSAIN ABRAHIM, WILLIS KATELYN M, DEVERAUX QUINN, ECKELMAN BRENDAN P, JONES KYLE S
Year of Publication 28.03.2018
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Year of Publication 28.03.2018
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다가 및 다중특이적 DR5-결합 융합 단백질
TIMMER JOHN C, RAZAI AMIR S, HUSSAIN ABRAHIM, WILLIS KATELYN M, DEVERAUX QUINN, ECKELMAN BRENDAN P, JONES KYLE S
Year of Publication 23.03.2018
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Year of Publication 23.03.2018
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다가 및 다중특이적 OX40-결합 융합 단백질
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Year of Publication 04.09.2018
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Year of Publication 04.09.2018
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다가 및 다중특이적 41BB-결합 융합 단백질
TIMMER JOHN C, HUSSAIN ABRAHIM, RAZAI AMIR S, DEVERAUX QUINN, HATA CHELSIE, KAPLAN MIKE, BECKLUND BRYAN, ECKELMAN BRENDAN P, PANDIT RAJAY, JONES KYLE S, RASON LUCAS
Year of Publication 29.08.2018
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Year of Publication 29.08.2018
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MULTIVALENT AND MULTISPECIFIC 41BB-BINDING FUSION PROTEINS
JONES, Kyle S, HUSSAIN, Abrahim, RASCON, Lucas, PANDIT, Rajay, HATA, Chelsie, KAPLAN, Mike, BECKLUND, Bryan, TIMMER, John C, RAZAI, Amir S, DEVERAUX, Quinn, ECKELMAN, Brendan P
Year of Publication 30.10.2024
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Year of Publication 30.10.2024
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MULTIVALENT AND MULTISPECIFIC GITR-BINDING FUSION PROTEINS
JONES, Kyle S, HUSSAIN, Abrahim, TIMMER, John C, RAZAI, Amir S, WILLIS, Katelyn M, DEVERAUX, Quinn, ECKELMAN, Brendan P
Year of Publication 06.09.2023
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Year of Publication 06.09.2023
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Multivalent and multispecific gitr-binding fusion proteins
Timmer, John C, Eckelman, Brendan P, Jones, Kyle S, Razai, Amir S, Willis, Katelyn M, Hussain, Abrahim, Deveraux, Quinn
Year of Publication 25.08.2023
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Year of Publication 25.08.2023
Patent
Multivalent and multispecific OX40-binding fusion proteins
Timmer, John C, Becklund, Bryan, Eckelman, Brendan P, Rascon, Lucas, Jones, Kyle S, Razai, Amir S, Pandit, Rajay, Kaplan, Mike, Hussain, Abrahim, Deveraux, Quinn, Hata, Chelsie
Year of Publication 22.02.2024
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Year of Publication 22.02.2024
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Multivalent and Multispecific 41BB-Binding Proteins
Timmer, John C, Becklund, Bryan, Eckelman, Brendan P, Rascon, Lucas, Macedo, Chelsie, Jones, Kyle S, Razai, Amir S, Pandit, Rajay, Kaplan, Mike, Hussain, Abrahim, Deveraux, Quinn
Year of Publication 28.12.2023
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Year of Publication 28.12.2023
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Multivalent and multispecific DR5-binding fusion proteins
JONES, Kyle S, HUSSAIN, Abrahim, TIMMER, John C, RAZAI, Amir S, WILLIS, Katelyn M, DEVERAUX, Quinn, ECKELMAN, Brendan P
Year of Publication 02.02.2023
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Year of Publication 02.02.2023
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Multivalent and multispecific OX40-binding fusion proteins
Timmer, John C, Becklund, Bryan, Eckelman, Brendan P, Rascon, Lucas, Jones, Kyle S, Razai, Amir S, Pandit, Rajay, Kaplan, Mike, Hussain, Abrahim, Deveraux, Quinn, Hata, Chelsie
Year of Publication 07.12.2023
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Year of Publication 07.12.2023
Patent
Multivalent and multispecific DR5-binding fusion proteins
Timmer, John C, Eckelman, Brendan P, Jones, Kyle S, Razai, Amir S, Willis, Katelyn M, Hussain, Abrahim, Deveraux, Quinn
Year of Publication 29.09.2022
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Year of Publication 29.09.2022
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PDL1-binding proteins
Timmer, John C, Becklund, Bryan, Eckelman, Brendan P, Rascon, Lucas, Macedo, Chelsie, Jones, Kyle S, Razai, Amir S, Pandit, Rajay, Kaplan, Mike, Hussain, Abrahim, Deveraux, Quinn
Year of Publication 31.01.2023
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Year of Publication 31.01.2023
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