LRRK2 Inhibition by BIIB122 in Healthy Participants and Patients with Parkinson's Disease
Jennings, Danna, Huntwork‐Rodriguez, Sarah, Vissers, Maurits F.J.M., Daryani, Vinay M., Diaz, Dolores, Goo, Marisa S., Chen, John J., Maciuca, Romeo, Fraser, Kyle, Mabrouk, Omar S., Wetering de Rooij, Jeroen, Heuberger, Jules A.A.C., Groeneveld, Geert Jan, Borin, Marie T., Cruz‐Herranz, Andrés, Graham, Danielle, Scearce‐Levie, Kimberly, De Vicente, Javier, Henry, Anastasia G., Chin, Peter, Ho, Carole, Troyer, Matthew D.
Published in Movement disorders (01.03.2023)
Published in Movement disorders (01.03.2023)
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A leucine‐rich repeat kinase 2 (LRRK2) pathway biomarker characterization study in patients with Parkinson's disease with and without LRRK2 mutations and healthy controls
Vissers, Maurits F. J. M., Troyer, Matthew D., Thijssen, Eva, Pereira, Diana R., Heuberger, | Jules A. A. C., Groeneveld, Geert Jan, Huntwork‐Rodriguez, Sarah
Published in Clinical and translational science (01.08.2023)
Published in Clinical and translational science (01.08.2023)
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Journal Article
DLK initiates a transcriptional program that couples apoptotic and regenerative responses to axonal injury
Watkins, Trent A., Wang, Bei, Huntwork-Rodriguez, Sarah, Yang, Jing, Jiang, Zhiyu, Eastham-Anderson, Jeffrey, Modrusan, Zora, Kaminker, Joshua S., Tessier-Lavigne, Marc, Lewcock, Joseph W.
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2013)
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JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis
Huntwork-Rodriguez, Sarah, Wang, Bei, Watkins, Trent, Ghosh, Arundhati Sengupta, Pozniak, Christine D, Bustos, Daisy, Newton, Kim, Kirkpatrick, Donald S, Lewcock, Joseph W
Published in The Journal of cell biology (02.09.2013)
Published in The Journal of cell biology (02.09.2013)
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The Current State-of-the Art of LRRK2-Based Biomarker Assay Development in Parkinson’s Disease
Rideout, Hardy J., Chartier-Harlin, Marie-Christine, Fell, Matthew J., Hirst, Warren D., Huntwork-Rodriguez, Sarah, Leyns, Cheryl E. G., Mabrouk, Omar S., Taymans, Jean-Marc
Published in Frontiers in neuroscience (18.08.2020)
Published in Frontiers in neuroscience (18.08.2020)
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Journal Article
Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult
Larhammar, Martin, Huntwork-Rodriguez, Sarah, Jiang, Zhiyu, Solanoy, Hilda, Sengupta Ghosh, Arundhati, Wang, Bei, Kaminker, Joshua S, Huang, Kevin, Eastham-Anderson, Jeffrey, Siu, Michael, Modrusan, Zora, Farley, Madeline M, Tessier-Lavigne, Marc, Lewcock, Joseph W, Watkins, Trent A
Published in eLife (25.04.2017)
Published in eLife (25.04.2017)
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Differential regulation of evoked and spontaneous neurotransmitter release by C-terminal modifications of complexin
Buhl, Lauren K., Jorquera, Ramon A., Akbergenova, Yulia, Huntwork-Rodriguez, Sarah, Volfson, Dina, Littleton, J. Troy
Published in Molecular and cellular neuroscience (01.01.2013)
Published in Molecular and cellular neuroscience (01.01.2013)
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Journal Article
METHODS OF MODULATING DLK STABILITY
KIRKPATRICK DONALD, GHOSH ARUNDHATI SENGUPTA, HUNTWORK RODRIGUEZ SARAH, BUSTOS DAISY, LEWCOCK JOSEPH WESLEY
Year of Publication 06.11.2015
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Year of Publication 06.11.2015
Patent
Association of caffeine and related analytes with resistance to Parkinson disease among LRRK2 mutation carriers: A metabolomic study
Crotty, Grace F, Maciuca, Romeo, Macklin, Eric A, Wang, Junhua, Montalban, Manuel, Davis, Sonnet S, Alkabsh, Jamal I, Bakshi, Rachit, Chen, Xiqun, Ascherio, Alberto, Astarita, Giuseppe, Huntwork-Rodriguez, Sarah, Schwarzschild, Michael A
Published in Neurology (15.12.2020)
Published in Neurology (15.12.2020)
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Complexin controls spontaneous and evoked neurotransmitter release by regulating the timing and properties of synaptotagmin activity
Jorquera, Ramon A, Huntwork-Rodriguez, Sarah, Akbergenova, Yulia, Cho, Richard W, Littleton, J Troy
Published in The Journal of neuroscience (12.12.2012)
Published in The Journal of neuroscience (12.12.2012)
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Genetic analysis reveals that amyloid precursor protein and death receptor 6 function in the same pathway to control axonal pruning independent of β-secretase
Olsen, Olav, Kallop, Dara Y, McLaughlin, Todd, Huntwork-Rodriguez, Sarah, Wu, Zhuhao, Duggan, Cynthia D, Simon, David J, Lu, Yanmei, Easley-Neal, Courtney, Takeda, Kentaro, Hass, Philip E, Jaworski, Alexander, O'Leary, Dennis D M, Weimer, Robby M, Tessier-Lavigne, Marc
Published in The Journal of neuroscience (07.05.2014)
Published in The Journal of neuroscience (07.05.2014)
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Phospho-Rab antibodies, assays and methods of use thereof
Moerke, Nathan, Wang, Xiang, Dugas, Jason C, Maloney, Michael T, Huntwork-Rodriguez, Sarah, Negrou, Ella, Henry, Anastasia
Year of Publication 30.05.2023
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Year of Publication 30.05.2023
Patent
PHOSPHO-RAB ANTIBODIES, ASSAYS AND METHODS OF USE THEREOF
Moerke, Nathan, Wang, Xiang, Dugas, Jason C, Maloney, Michael T, Huntwork-Rodriguez, Sarah, Negrou, Ella, Henry, Anastasia
Year of Publication 20.05.2021
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Year of Publication 20.05.2021
Patent