Defining tumor resistance to PD-1 pathway blockade: recommendations from the first meeting of the SITC Immunotherapy Resistance Taskforce
Kluger, Harriet M., Tawbi, Hussein A., Ascierto, Maria L., Bowden, Michaela, Callahan, Margaret K., Cha, Edward, Chen, Helen X., Drake, Charles G., Feltquate, David M., Ferris, Robert L., Gulley, James L., Gupta, Shilpa, Humphrey, Rachel W., LaVallee, Theresa M., Le, Dung T., Hubbard-Lucey, Vanessa M., Papadimitrakopoulou, Vassiliki A., Postow, Michael A., Rubin, Eric H., Sharon, Elad, Taube, Janis M., Topalian, Suzanne L., Zappasodi, Roberta, Sznol, Mario, Sullivan, Ryan J.
Published in Journal for immunotherapy of cancer (01.03.2020)
Published in Journal for immunotherapy of cancer (01.03.2020)
Get full text
Journal Article
Opportunities and Challenges in the Development of Experimental Drug Combinations for Cancer
W. Humphrey, Rachel, M. Brockway-Lunardi, Laura, T. Bonk, David, Dohoney, Kathleen M., Doroshow, James H., Meech, Sandra J., Ratain, Mark J., Topalian, Suzanne L., M. Pardoll, Drew
Published in JNCI : Journal of the National Cancer Institute (17.08.2011)
Published in JNCI : Journal of the National Cancer Institute (17.08.2011)
Get full text
Journal Article
Maximizing the value of phase III trials in immuno-oncology: A checklist from the Society for Immunotherapy of Cancer (SITC)
Atkins, Michael B, Abu-Sbeih, Hamzah, Ascierto, Paolo A, Bishop, Michael R, Chen, Daniel S, Dhodapkar, Madhav, Emens, Leisha A, Ernstoff, Marc S, Ferris, Robert L, Greten, Tim F, Gulley, James L, Herbst, Roy S, Humphrey, Rachel W, Larkin, James, Margolin, Kim A, Mazzarella, Luca, Ramalingam, Suresh S, Regan, Meredith M, Rini, Brian I, Sznol, Mario
Published in Journal for immunotherapy of cancer (01.09.2022)
Published in Journal for immunotherapy of cancer (01.09.2022)
Get full text
Journal Article
Detection of Serum Antibodies to a Kaposi's Sarcoma—Associated Herpesvirus-Specific Peptide
Davis, David A., Humphrey, Rachel W., Newcomb, Fonda M., O'Brien, Thomas R., Goedert, James J., Straus, Stephen E., Yarchoan, Robert
Published in The Journal of infectious diseases (01.05.1997)
Published in The Journal of infectious diseases (01.05.1997)
Get full text
Journal Article
Recommended changes to oncology clinical trial design: Revolution or evolution?
Ratain, Mark J, Humphrey, Rachel W, Gordon, Gary B, Fyfe, Gwen, Adamson, Peter C, Fleming, Thomas R, Stadler, Walter M, Berry, Donald A, Peck, Carl C
Published in European journal of cancer (1990) (01.01.2008)
Published in European journal of cancer (1990) (01.01.2008)
Get full text
Journal Article
Clinical pharmacokinetics of bdtx-189, an inhibitor of allosteric ErbB mutations, in patients with advanced solid malignancies in MasterKey-01 study
Waters, Nigel, Patel, Manish R., Schram, Alison M., Rodon Ahnert, Jordi, Jauhari, Shekeab, Sachdev, Jasgit C., Zhu, Viola Weijia, LoRusso, Patricia, Nguyen, Danny, Hong, David S., Tarilonte, Leticia, Humphrey, Rachel W., Janne, Pasi A., Hamilton, Erika P., Witt, Karsten
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
Get full text
Journal Article
Safety and preliminary efficacy from the phase 1 portion of MasterKey-01: A First-in-human dose-escalation study to determine the recommended phase 2 dose (RP2D), pharmacokinetics (PK) and preliminary antitumor activity of BDTX-189, an inhibitor of allosteric ErbB mutations, in patients (pts) with advanced solid malignancies
Schram, Alison M., Rodon Ahnert, Jordi, Patel, Manish R., Jauhari, Shekeab, Sachdev, Jasgit C., Zhu, Viola Weijia, LoRusso, Patricia, Nguyen, Danny, Le, Xiuning, O'Connor, Matthew, Waters, Nigel, Cook, Carl, Witt, Karsten, Humphrey, Rachel W., Janne, Pasi A., Hamilton, Erika P.
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
Get full text
Journal Article
Preliminary single-dose clinical pharmacokinetics of an anti–PD-L1 Probody therapeutic (Pb-Tx) in cancer patients
Stroh, Mark, Serwer, Laura, Lu, Hong, Huels, Vanessa, Wong, Chihunt, Zheng, Beiyao, Millard, Bjorn L., Apgar, Joshua F., Zheng, Nancy, Richardson, Jennifer Hope, Will, Matthias, Humphrey, Rachel W.
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
Get full text
Journal Article
PROCLAIM-001: A first-in-human trial to assess tolerability of the protease-activatable anti-PD-L1 Probody CX-072 in solid tumors and lymphomas
Spira, Alexander I., Middleton, Mark R., Naing, Aung, Autio, Karen A., Nemunaitis, John J., Bendell, Johanna C., Gordon, Michael, Humphrey, Rachel W., Wong, Chihunt, Rizvi, Naiyer A.
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
Get full text
Journal Article
Preliminary results of the first-in-human, dose-finding PROCLAIM-CX-072 trial of the PD-L1 Probody therapeutic CX-072 as monotherapy in patients (pts) with advanced solid tumors
Autio, Karen A., Arkenau, Hendrik-Tobias, O'Neil, Bert H., Bendell, Johanna C., El-Khoueiry, Anthony, Strauss, James, Weise, Amy, Uboha, Nataliya Volodymyrivna, Rizvi, Naiyer A., Zheng, Beiyao, Desnoyers, Luc, Stroh, Mark, Carman, Lori, Humphrey, Rachel W., Will, Matthias, Boni, Valentina, Spira, Alexander I., Naing, Aung
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
Get full text
Journal Article
Preliminary interim results of the first-in-human, dose-finding PROCLAIM-CX-072 trial of the PD-L1 Probody therapeutic (Pb-Tx) CX-072 in combination with ipilimumab (ipi) in patients (pts) with advanced solid tumors
Sanborn, Rachel E., Menke, Catharina Wilhelmina, Autio, Karen A., Arkenau, Hendrik-Tobias, Corbacho, Javier Garcia, LoRusso, Patricia, Plummer, Elizabeth Ruth, Uboha, Nataliya Volodymyrivna, Freeman, Morganna Louise, Wydmanski, Jerzy, Huels, Vanessa, Zheng, Beiyao, Will, Matthias, Humphrey, Rachel W., Thistlethwaite, Fiona, de Vries, Elisabeth G.E., El-Khoueiry, Anthony B.
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
Get full text
Journal Article
Phase II trial with dose titration of paclitaxel for the therapy of human immunodeficiency virus-associated Kaposi's sarcoma
Welles, L, Saville, M W, Lietzau, J, Pluda, J M, Wyvill, K M, Feuerstein, I, Figg, W D, Lush, R, Odom, J, Wilson, W H, Fajardo, M T, Humphrey, R W, Feigal, E, Tuck, D, Steinberg, S M, Broder, S, Yarchoan, R
Published in Journal of clinical oncology (01.03.1998)
Published in Journal of clinical oncology (01.03.1998)
Get more information
Journal Article
Relative Potency of Protease Inhibitors in Monocytes/Macrophages Acutely and Chronically Infected with Human Immunodeficiency Virus
Perno, Carlo-Federico, Newcomb, Fonda M., Davis, David A., Aquaro, Stefano, Humphrey, Rachel W., Caliò, Raffaele, Yarchoan, Robert
Published in The Journal of infectious diseases (01.08.1998)
Published in The Journal of infectious diseases (01.08.1998)
Get full text
Journal Article
Endpoints and other considerations in phase I studies of targeted anticancer therapy : Recommendations from the task force on Methodology for the Development of Innovative Cancer Therapies (MDICT). Commentary
RATAIN, Mark J, HUMPHREY, Rachel W, CALUERT, A. Hilary, GIACCONE, Giuseppe, LOBBEZOO, Marinus W, SEYMOUR, Lesley K, EISENHAUER, Elizabeth A, GORDON, Gary B, FYFE, Gwen, ADAMSON, Peter C, FLEMING, Thomas R, STADLERA, Walter M, BERRY, Donald A, PECK, Carl C, BOOTH, Christopher M
Published in European journal of cancer (1990) (2008)
Get full text
Published in European journal of cancer (1990) (2008)
Journal Article
Design and conduct of phase II studies of targeted anticancer therapy : Recommendations from the task force on methodology for the development of innovative cancer therapies (MDICT). Commentary
RATAIN, Mark J, HUMPHREY, Rachel W, CALUERT, A. Hilary, GIACCONE, Giuseppe, LOBBEZOO, Marinus W, EISENHAUER, Elizabeth A, SEYMOUR, Lesley K, GORDON, Gary B, FYFE, Gwen, ADAMSON, Peter C, FLEMING, Thomas R, STADLER, Walter M, BERRY, Donald A, PECK, Carl C, BOOTH, Christopher M
Published in European journal of cancer (1990) (2008)
Get full text
Published in European journal of cancer (1990) (2008)
Journal Article
Kaposi's sarcoma (KS)-associated herpesvirus-like DNA sequences in peripheral blood mononuclear cells : Association with KS and persistence in patients receiving anti-herpesvirus drugs
HUMPHREY, R. W, O'BRIEN, T. R, NEWCOMB, F. M, NISHIHARA, H, WYVILL, K. M, RAMOS, G. A, SAVILLE, M. W, GOEDERT, J. J, STRAUS, S. E, YARCHOAN, R
Published in Blood (01.07.1996)
Published in Blood (01.07.1996)
Get full text
Journal Article
Mitochondrial and myocardial performance. Response to ischemia and reperfusion
Weinstein, E S, Spector, M L, Adams, E M, Yokum, M D, Humphrey, R W, Fry, D E
Published in Archives of surgery (Chicago. 1960) (01.03.1986)
Published in Archives of surgery (Chicago. 1960) (01.03.1986)
Get more information
Journal Article