TRPM7 in neurodevelopment and therapeutic prospects for neurodegenerative disease
Luo, Zhengwei, Zhang, Xinyang, Fleig, Andrea, Romo, Daniel, Hull, Kenneth G., Horgen, F. David, Sun, Hong-Shuo, Feng, Zhong-Ping
Published in Cell calcium (Edinburgh) (01.06.2024)
Published in Cell calcium (Edinburgh) (01.06.2024)
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Journal Article
Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A
Naineni, Sai Kiran, Liang, Jason, Hull, Kenneth, Cencic, Regina, Zhu, Mingzhao, Northcote, Peter, Teesdale-Spittle, Paul, Romo, Daniel, Nagar, Bhushan, Pelletier, Jerry
Published in Cell chemical biology (17.06.2021)
Published in Cell chemical biology (17.06.2021)
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Dopamine-Derived Guanidine Alkaloids from a Didemnidae Tunicate: Isolation, Synthesis, and Biological Activities
Sakai, Ryuichi, Matsumura, Ken, Uchimasu, Hajime, Miyako, Kei, Taniguchi, Tohru, Kovvuri, V. Raghavendra Rao, Acharige, Anjana Delpe, Hull, Kenneth G., Romo, Daniel, Thaveepornkul, Lakkana, Chimnaronk, Sarin, Miyamoto, Hiroko, Takada, Ayato, Watari, Hiromi, Fujita, Masaki J., Sakaue, Jiro
Published in Journal of organic chemistry (03.05.2024)
Published in Journal of organic chemistry (03.05.2024)
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Journal Article
Molecular Mechanism for Attractant Signaling to DHMA by E. coli Tsr
Orr, Asuka A., Yang, Jingyun, Sule, Nitesh, Chawla, Ravi, Hull, Kenneth G., Zhu, Mingzhao, Romo, Daniel, Lele, Pushkar P., Jayaraman, Arul, Manson, Michael D., Tamamis, Phanourios
Published in Biophysical journal (21.01.2020)
Published in Biophysical journal (21.01.2020)
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Interrogation of the Substrate Profile and Catalytic Properties of the Phosphotriesterase from Sphingobium sp. Strain TCM1: An Enzyme Capable of Hydrolyzing Organophosphate Flame Retardants and Plasticizers
Xiang, Dao Feng, Bigley, Andrew N, Ren, Zhongjie, Xue, Haoran, Hull, Kenneth G, Romo, Daniel, Raushel, Frank M
Published in Biochemistry (Easton) (29.12.2015)
Published in Biochemistry (Easton) (29.12.2015)
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Journal Article
A Novel Actin Binding Drug with In Vivo Efficacy
Ravichandran, Akshaya, Geng, Mengxin, Hull, Kenneth G, Li, Jing, Romo, Daniel, Lu, Shi-En, Albee, Aaron, Nutter, Christopher, Gordon, Donna M, Ghannoum, Mahmoud A, Lockless, Steve W, Smith, Leif
Published in Antimicrobial agents and chemotherapy (01.01.2019)
Published in Antimicrobial agents and chemotherapy (01.01.2019)
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Journal Article
Chemical Mechanism of the Phosphotriesterase from Sphingobium sp. Strain TCM1, an Enzyme Capable of Hydrolyzing Organophosphate Flame Retardants
Bigley, Andrew N, Xiang, Dao Feng, Ren, Zhongjie, Xue, Haoran, Hull, Kenneth G, Romo, Daniel, Raushel, Frank M
Published in Journal of the American Chemical Society (09.03.2016)
Published in Journal of the American Chemical Society (09.03.2016)
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Journal Article
Transient Receptor Potential Melastatin 7 (TRPM7) Ion Channel Inhibitors: Preliminary SAR and Conformational Studies of Xenicane Diterpenoids from the Hawaiian Soft Coral Sarcothelia edmondsoni
Yao, Guangmin, Parris, Matthew R., Kuo, W. Cedric, Pörzgen, Peter, Castillo, Brandi, Mason, Evan S., Chinchilla, Andres, Huang, Junhao, Suzuki, Sayuri, Ross, Rylee, Akana, Ellis, Vander Schuit, Savana, Miller, Steven P., Penner, Reinhold, Sun, Hong-Shuo, Feng, Zhong-Ping, Hull, Kenneth G., Romo, Daniel, Fleig, Andrea, Horgen, F. David
Published in Journal of natural products (Washington, D.C.) (26.04.2024)
Published in Journal of natural products (Washington, D.C.) (26.04.2024)
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Journal Article
Bioactive Seco-Lanostane-Type Triterpenoids from the Roots of Leplaea mayombensis
Sidjui, Lazare S, Eyong, Kenneth O, Hull, Kenneth G, Folefoc, Gabriel N, Leddet, Valérie M, Herbette, Gaëtan, Ollivier, Evelyne, Taube, Joseph, Klausmeyer, Kevin, Romo, Daniel
Published in Journal of natural products (Washington, D.C.) (27.10.2017)
Published in Journal of natural products (Washington, D.C.) (27.10.2017)
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Journal Article
Second-Shell Amino Acid R266 Helps Determine N‑Succinylamino Acid Racemase Reaction Specificity in Promiscuous N‑Succinylamino Acid Racemase/o‑Succinylbenzoate Synthase Enzymes
Truong, Dat P, Rousseau, Simon, Machala, Benjamin W, Huddleston, Jamison P, Zhu, Mingzhao, Hull, Kenneth G, Romo, Daniel, Raushel, Frank M, Sacchettini, James C, Glasner, Margaret E
Published in Biochemistry (Easton) (21.12.2021)
Published in Biochemistry (Easton) (21.12.2021)
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Journal Article
Creating novel translation inhibitors to target pro-survival proteins in chronic lymphocytic leukemia
Chen, Rong, Zhu, Mingzhao, Chaudhari, Rajan R., Robles, Omar, Chen, Yuling, Skillern, Wesley, Qin, Qun, Wierda, William G., Zhang, Shuxing, Hull, Kenneth G., Romo, Daniel, Plunkett, William
Published in Leukemia (01.07.2019)
Published in Leukemia (01.07.2019)
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Journal Article
Synthetic Tigliane Intermediates Engage Thiols to Induce Potent Cell Line Selective Anti‐Cancer Activity
Chow, Sharon, Krainz, Tanja, Bettencourt, Christian J., Broit, Natasa, Ferguson, Blake, Zhu, Mingzhao, Hull, Kenneth G., Pierens, Gregory K., Bernhardt, Paul V., Parsons, Peter G., Romo, Daniel, Boyle, Glen M., Williams, Craig M.
Published in Chemistry : a European journal (21.10.2020)
Published in Chemistry : a European journal (21.10.2020)
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Journal Article
Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV
Manchester, John I., Dussault, Daemian D., Rose, Jonathan A., Boriack-Sjodin, P. Ann, Uria-Nickelsen, Maria, Ioannidis, Georgine, Bist, Shanta, Fleming, Paul, Hull, Kenneth G.
Published in Bioorganic & medicinal chemistry letters (01.08.2012)
Published in Bioorganic & medicinal chemistry letters (01.08.2012)
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Journal Article
Waixenicin A, a marine-derived TRPM7 inhibitor: a promising CNS drug lead
Sun, Hong-Shuo, Horgen, F. David, Romo, Daniel, Hull, Kenneth G., Kiledal, Sigrid A., Fleig, Andrea, Feng, Zhong-Ping
Published in Acta pharmacologica Sinica (01.12.2020)
Published in Acta pharmacologica Sinica (01.12.2020)
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Journal Article
Comparison of Alicyclobacillus acidocaldarius o‑Succinylbenzoate Synthase to Its Promiscuous N‑Succinylamino Acid Racemase/o‑Succinylbenzoate Synthase Relatives
Odokonyero, Denis, McMillan, Andrew W, Ramagopal, Udupi A, Toro, Rafael, Truong, Dat P, Zhu, Mingzhao, Lopez, Mariana S, Somiari, Belema, Herman, Meghann, Aziz, Asma, Bonanno, Jeffrey B, Hull, Kenneth G, Burley, Stephen K, Romo, Daniel, Almo, Steven C, Glasner, Margaret E
Published in Biochemistry (Easton) (03.07.2018)
Published in Biochemistry (Easton) (03.07.2018)
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Journal Article
Novel topoisomerase inhibitors: microbiological characterisation and in vivo efficacy of pyrimidines
Uria-Nickelsen, Maria, Neckermann, Georg, Sriram, Shubha, Andrews, Beth, Manchester, John I, Carcanague, Dan, Stokes, Suzanne, Hull, Kenneth G
Published in International journal of antimicrobial agents (01.04.2013)
Published in International journal of antimicrobial agents (01.04.2013)
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Journal Article
Necator americanus Ancylostoma Secreted Protein-2 ( Na -ASP-2) Binds an Ascaroside (ascr#3) in Its Fatty Acid Binding Site
El Atab, Ola, Darwiche, Rabih, Truax, Nathanyal J, Schneiter, Roger, Hull, Kenneth G, Romo, Daniel, Asojo, Oluwatoyin A
Published in Frontiers in chemistry (17.12.2020)
Published in Frontiers in chemistry (17.12.2020)
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Journal Article
Triterpenoids from the stem bark of Vitellaria paradoxa (Sapotaceae) and derived esters exhibit cytotoxicity against a breast cancer cell line
Eyong, Kenneth O., Bairy, Guerisson, Eno, Anna A., Taube, Joseph, Hull, Kenneth G., Folefoc, Gabriel N., Foyet, Harquin S., Romo, Daniel
Published in Medicinal chemistry research (2018)
Published in Medicinal chemistry research (2018)
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Journal Article
A strategy for dual inhibition of the proteasome and fatty acid synthase with belactosin C-orlistat hybrids
Zhu, Mingzhao, Harshbarger, Wayne D., Robles, Omar, Krysiak, Joanna, Hull, Kenneth G., Cho, Sung Wook, Richardson, Robyn D., Yang, Yanyan, Garcia, Andres, Spiegelman, Lindsey, Ramirez, Bianca, Wilson, Christopher T., Yau, Ju Anne, Moore, James T., Walker, Caitlen B., Sacchettini, James C., Liu, Wenshe R., Sieber, Stephan A., Smith, Jeffrey W., Romo, Daniel
Published in Bioorganic & medicinal chemistry (01.06.2017)
Published in Bioorganic & medicinal chemistry (01.06.2017)
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Journal Article
Antiproliferative activity of naphthoquinones and indane carboxylic acids from lapachol against a panel of human cancer cell lines
Eyong, Kenneth O., Ketsemen, Herve L., Zhao, Zhenze, Du, Liqin, Ingels, Aude, Mathieu, Veronique, Kornienko, Alexander, Hull, Kenneth G., Folefoc, Gabriel N., Baskaran, Sundarababu, Romo, Daniel
Published in Medicinal chemistry research (01.06.2020)
Published in Medicinal chemistry research (01.06.2020)
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