Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice
Baldan, Lissandra Castellan, Williams, Kyle A, Gallezot, Jean-Dominique, Pogorelov, Vladimir, Rapanelli, Maximiliano, Crowley, Michael, Anderson, George M, Loring, Erin, Gorczyca, Roxanne, Billingslea, Eileen, Wasylink, Suzanne, Panza, Kaitlyn E, Ercan-Sencicek, A Gulhan, Krusong, Kuakarun, Leventhal, Bennett L, Ohtsu, Hiroshi, Bloch, Michael H, Hughes, Zoë A, Krystal, John H, Mayes, Linda, de Araujo, Ivan, Ding, Yu-Shin, State, Matthew W, Pittenger, Christopher
Published in Neuron (Cambridge, Mass.) (08.01.2014)
Published in Neuron (Cambridge, Mass.) (08.01.2014)
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Journal Article
The BTBR mouse model of autism spectrum disorders has learning and attentional impairments and alterations in acetylcholine and kynurenic acid in prefrontal cortex
McTighe, Stephanie M, Neal, Sarah J, Lin, Qian, Hughes, Zoë A, Smith, Daniel G
Published in PloS one (24.04.2013)
Published in PloS one (24.04.2013)
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Journal Article
Receptor and behavioral pharmacology of WAY-267464, a non-peptide oxytocin receptor agonist
Ring, Robert H., Schechter, Lee E., Leonard, Sarah K., Dwyer, Jason M., Platt, Brian J., Graf, Radka, Grauer, Steven, Pulicicchio, Claudine, Resnick, Lynn, Rahman, Zia, Sukoff Rizzo, Stacey J., Luo, Bin, Beyer, Chad E., Logue, Sheree F., Marquis, Karen L., Hughes, Zoë A., Rosenzweig-Lipson, Sharon
Published in Neuropharmacology (2010)
Published in Neuropharmacology (2010)
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Journal Article
Effects of a Balanced Translocation between Chromosomes 1 and 11 Disrupting the DISC1 Locus on White Matter Integrity
Whalley, Heather C, Dimitrova, Rali, Sprooten, Emma, Dauvermann, Maria R, Romaniuk, Liana, Duff, Barbara, Watson, Andrew R, Moorhead, Bill, Bastin, Mark, Semple, Scott I, Giles, Stephen, Hall, Jeremy, Thomson, Pippa, Roberts, Neil, Hughes, Zoe A, Brandon, Nick J, Dunlop, John, Whitcher, Brandon, Blackwood, Douglas H R, McIntosh, Andrew M, Lawrie, Stephen M
Published in PloS one (23.06.2015)
Published in PloS one (23.06.2015)
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Journal Article
5-HT1A receptor antagonism reverses and prevents fluoxetine-induced sexual dysfunction in rats
Sukoff Rizzo, Stacey J., Pulicicchio, Claudine, Malberg, Jessica E., Andree, Terrance H., Stack, Gary P., Hughes, Zoë A., Schechter, Lee E., Rosenzweig-Lipson, Sharon
Published in The international journal of neuropsychopharmacology (01.09.2009)
Published in The international journal of neuropsychopharmacology (01.09.2009)
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Journal Article
Critical data-based re-evaluation of minocycline as a putative specific microglia inhibitor
Möller, Thomas, Bard, Frédérique, Bhattacharya, Anindya, Biber, Knut, Campbell, Brian, Dale, Elena, Eder, Claudia, Gan, Li, Garden, Gwenn A., Hughes, Zoë A., Pearse, Damien D., Staal, Roland G. W., Sayed, Faten A., Wes, Paul D., Boddeke, Hendrikus W. G. M.
Published in Glia (01.10.2016)
Published in Glia (01.10.2016)
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Flow cytometric analysis of BrdU incorporation as a high-throughput method for measuring adult neurogenesis in the mouse
Balu, Darrick T., Hodes, Georgia E., Hill, Tiffany E., Ho, Nancy, Rahman, Zia, Bender, Corey N., Ring, Robert H., Dwyer, Jason M., Rosenzweig-Lipson, Sharon, Hughes, Zoe A., Schechter, Lee E., Lucki, Irwin
Published in Journal of pharmacological and toxicological methods (01.03.2009)
Published in Journal of pharmacological and toxicological methods (01.03.2009)
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Journal Article
Translational Pharmacology of PRAX‐944, a Novel T‐Type Calcium Channel Blocker in Development for the Treatment of Essential Tremor
Scott, Liam, Puryear, Corey B., Belfort, Gabriel M., Raines, Shane, Hughes, Zoë A., Matthews, Lillian G., Ravina, Bernard, Wittmann, Marion
Published in Movement disorders (01.06.2022)
Published in Movement disorders (01.06.2022)
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Journal Article
The novel persistent sodium current inhibitor PRAX‐562 has potent anticonvulsant activity with improved protective index relative to standard of care sodium channel blockers
Kahlig, Kristopher M., Scott, Liam, Hatch, Robert J., Griffin, Andrew, Martinez Botella, Gabriel, Hughes, Zoë A., Wittmann, Marion
Published in Epilepsia (Copenhagen) (01.03.2022)
Published in Epilepsia (Copenhagen) (01.03.2022)
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Journal Article
GM-1020: a novel, orally bioavailable NMDA receptor antagonist with rapid and robust antidepressant-like effects at well-tolerated doses in rodents
Klein, Adam K, Austin, Eric W, Cunningham, Michael J, Dvorak, Dino, Gatti, Silvia, Hulls, Sarah K, Kiss, Laszlo, Kruegel, Andrew C, Marek, Gerard J, Papp, Mariusz, Sporn, Jonathan, Hughes, Zoë A
Published in Neuropsychopharmacology (New York, N.Y.) (01.05.2024)
Published in Neuropsychopharmacology (New York, N.Y.) (01.05.2024)
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Journal Article
The isozyme selective phosphodiesterase-4 inhibitor, ABI-4, attenuates the effects of lipopolysaccharide in human cells and rodent models of peripheral and CNS inflammation
Hedde, Joseph R, Hanks, Ashley N, Schmidt, Christopher J, Hughes, Zoë A
Published in Brain, behavior, and immunity (01.08.2017)
Published in Brain, behavior, and immunity (01.08.2017)
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Journal Article
The metabotropic glutamate receptor 7 allosteric modulator AMN082: a monoaminergic agent in disguise?
Sukoff Rizzo, Stacey J, Leonard, Sarah K, Gilbert, Adam, Dollings, Paul, Smith, Deborah L, Zhang, Mei-Yi, Di, Li, Platt, Brian J, Neal, Sarah, Dwyer, Jason M, Bender, Corey N, Zhang, Jean, Lock, Tim, Kowal, Dianne, Kramer, Angela, Randall, Andrew, Huselton, Christine, Vishwanathan, Karthick, Tse, Susanna Y, Butera, John, Ring, Robert H, Rosenzweig-Lipson, Sharon, Hughes, Zoë A, Dunlop, John
Published in The Journal of pharmacology and experimental therapeutics (01.07.2011)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2011)
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Journal Article
Defining the brain circuits involved in psychiatric disorders: IMI-NEWMEDS
Artigas, Francesc, Schenker, Esther, Celada, Pau, Spedding, Michael, Lladó-Pelfort, Laia, Jurado, Noemi, Núñez, Mercedes, Santana, Noemi, Troyano-Rodriguez, Eva, Riga, Maurizio S., van den Munkhof, Hanna, Castañé, Anna, Shaban, Hamdy, Jay, Thérèse M., Tripathi, Anushree, Godsil, Bill P., Sebban, Claude, Mariani, Jean, Faure, Philippe, Takkilah, Samir, Hughes, Zoe A., Siok, Chester J., Hajos, Mihaily, Wicke, Karsten, Gass, Natalia, Weber-Fahr, Wolfgang, Sartorius, Alexander, Becker, Robert, Didriksen, Michael, Bastlund, Jesper F., Tricklebank, Mark, Risterucci, Céline, Meyer-Lindenberg, Andreas, Schwarz, Adam J.
Published in Nature reviews. Drug discovery (01.01.2017)
Published in Nature reviews. Drug discovery (01.01.2017)
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First-in-Human Evaluation of 18F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B
Wakabayashi, Yuichi, Stenkrona, Per, Arakawa, Ryosuke, Yan, Xuefeng, Van Buskirk, Maia G, Jenkins, Madeline D, Santamaria, Jose A Montero, Maresca, Kevin P, Takano, Akihiro, Liow, Jeih-San, Chappie, Thomas A, Varrone, Andrea, Nag, Sangram, Zhang, Lei, Hughes, Zoë A, Schmidt, Christopher J, Doran, Shawn D, Mannes, Andrew, Zanotti-Fregonara, Paolo, Ooms, Maarten, Morse, Cheryl L, Zoghbi, Sami S, Halldin, Christer, Pike, Victor W, Innis, Robert B
Published in The Journal of nuclear medicine (1978) (01.12.2022)
Published in The Journal of nuclear medicine (1978) (01.12.2022)
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Journal Article
Ablation of the Locus Coeruleus Increases Oxidative Stress in Tg-2576 Transgenic but Not Wild-Type Mice
Boudonck, Kurt, Hurko, Orest, Gonzales, Cathleen, Hughes, Zoe A., Jacobsen, J. Steve, Reinhart, Peter H., Crowther, Daniel
Published in International journal of alzheimer's disease (2010)
Published in International journal of alzheimer's disease (2010)
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