Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds
Delfosse, Vanessa, Dendele, Béatrice, Huet, Tiphaine, Grimaldi, Marina, Boulahtouf, Abdelhay, Gerbal-Chaloin, Sabine, Beucher, Bertrand, Roecklin, Dominique, Muller, Christina, Rahmani, Roger, Cavaillès, Vincent, Daujat-Chavanieu, Martine, Vivat, Valérie, Pascussi, Jean-Marc, Balaguer, Patrick, Bourguet, William
Published in Nature communications (03.09.2015)
Published in Nature communications (03.09.2015)
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A Vitamin D Receptor Selectively Activated by Gemini Analogs Reveals Ligand Dependent and Independent Effects
Huet, Tiphaine, Laverny, Gilles, Ciesielski, Fabrice, Molnár, Ferdinand, Ramamoorthy, Thanuja Gali, Belorusova, Anna Y., Antony, Pierre, Potier, Noelle, Metzger, Daniel, Moras, Dino, Rochel, Natacha
Published in Cell reports (Cambridge) (03.02.2015)
Published in Cell reports (Cambridge) (03.02.2015)
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Journal Article
The "Phantom Effect" of the Rexinoid LG100754: structural and functional insights
Sato, Yoshiteru, Ramalanjaona, Nick, Huet, Tiphaine, Potier, Noelle, Osz, Judit, Antony, Pierre, Peluso-Iltis, Carole, Poussin-Courmontagne, Pierre, Ennifar, Eric, Mély, Yves, Dejaegere, Annick, Moras, Dino, Rochel, Natacha
Published in PloS one (30.11.2010)
Published in PloS one (30.11.2010)
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Mechanistic insights into the synergistic activation of the RXR–PXR heterodimer by endocrine disruptor mixtures
Delfosse, Vanessa, Huet, Tiphaine, Harrus, Deborah, Granell, Meritxell, Bourguet, Maxime, Gardia-Parège, Caroline, Chiavarina, Barbara, Grimaldi, Marina, Le Mével, Sébastien, Blanc, Pauline, Huang, David, Gruszczyk, Jakub, Demeneix, Barbara, Cianférani, Sarah, Fini, Jean-Baptiste, Balaguer, Patrick, Bourguet, William
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2021)
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The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA recognition motifs
Arieti, Fabiana, Gabus, Caroline, Tambalo, Margherita, Huet, Tiphaine, Round, Adam, Thore, Stéphane
Published in Nucleic acids research (02.06.2014)
Published in Nucleic acids research (02.06.2014)
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Journal Article
Steroid receptor RNA activator : RNA binding, activity, and atomic model
Huet, Tiphaine, Miannay, Francois-Alexandre, Patton, Jeffrey R, Thore, Stephane
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
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Journal Article
Mechanistic insights into the synergistic activation ofthe RXR–PXR heterodimer by endocrinedisruptor mixtures
Delfosse, Vanessa, Huet, Tiphaine, Harrus, Deborah, Granell, Meritxell, Bourguet, Maxime, Gardia-Parège, Caroline, Chiavarina, Barbara, Grimaldi, Marina, Le Mével, Sébastien, Blanc, Pauline, Huang, David, Gruszczyk, Jakub, Demeneix, Barbara, Cianférani, Sarah, Fini, Jean-Baptiste, Balaguer, Patrick, Bourguet, William
Published in Acta crystallographica. Section A, Foundations and advances (14.08.2021)
Published in Acta crystallographica. Section A, Foundations and advances (14.08.2021)
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Journal Article
Structure-Function Relationships and Crystal Structures of the Vitamin D Receptor Bound 2 alpha-Methyl-(20S,23S)- and 2 alpha-Methyl-(20S,23R)-epoxymethano-1 alpha,25-dihydroxyvitamin D-3
Antony, Pierre, Sigueiro, Rita, Huet, Tiphaine, Sato, Yoshiteru, Ramalanjaona, Nick, Cezar Rodrigues, Luis, Mourino, Antonio, Moras, Dino, Rochel, Natacha
Published in Journal of medicinal chemistry (11.02.2010)
Published in Journal of medicinal chemistry (11.02.2010)
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Journal Article
Total chemical synthesis, refolding, and crystallographic structure of fully active immunophilin calstabin 2 (FKBP12.6)
Bacchi, Marine, Jullian, Magali, Sirigu, Serena, Fould, Benjamin, Huet, Tiphaine, Bruyand, Lisa, Antoine, Mathias, Vuillard, Laurent, Ronga, Luisa, Chavas, Leonard M. G., Nosjean, Olivier, Ferry, Gilles, Puget, Karine, Boutin, Jean A.
Published in Protein science (01.12.2016)
Published in Protein science (01.12.2016)
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Journal Article
Structure−Function Relationships and Crystal Structures of the Vitamin D Receptor Bound 2α-Methyl-(20S,23S)- and 2α-Methyl-(20S,23R)-epoxymethano-1α,25-dihydroxyvitamin D3
Antony, Pierre, Sigüeiro, Rita, Huet, Tiphaine, Sato, Yoshiteru, Ramalanjaona, Nick, Rodrigues, Luis Cezar, Mouriño, Antonio, Moras, Dino, Rochel, Natacha
Published in Journal of medicinal chemistry (11.02.2010)
Published in Journal of medicinal chemistry (11.02.2010)
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Journal Article
Total chemical synthesis, refolding, and crystallographic structure of fully active immunophilin calstabin 2 (FKBP12.6): Chemical Synthesis of Catalytically Active Calstabin and Mutants
Bacchi, Marine, Jullian, Magali, Sirigu, Serena, Fould, Benjamin, Huet, Tiphaine, Bruyand, Lisa, Antoine, Mathias, Vuillard, Laurent, Ronga, Luisa, Chavas, Leonard M. G., Nosjean, Olivier, Ferry, Gilles, Puget, Karine, Boutin, Jean A.
Published in Protein science (01.12.2016)
Published in Protein science (01.12.2016)
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Journal Article
Crystallization via tubing microfluidics permits both in situ and ex situ X‐ray diffraction
Gerard, Charline J. J., Ferry, Gilles, Vuillard, Laurent M., Boutin, Jean A., Chavas, Leonard M. G., Huet, Tiphaine, Ferte, Nathalie, Grossier, Romain, Candoni, Nadine, Veesler, Stéphane
Published in Acta crystallographica. Section F, Structural biology communications (01.10.2017)
Published in Acta crystallographica. Section F, Structural biology communications (01.10.2017)
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Journal Article
Design, Synthesis, Evaluation, and Structure of Vitamin D Analogues with Furan Side Chains
Fraga, Ramón, Zacconi, Flavia, Sussman, Fredy, Ordóñez-Morán, Paloma, Muñoz, Alberto, Huet, Tiphaine, Molnár, Ferdinand, Moras, Dino, Rochel, Natacha, Maestro, Miguel, Mouriño, Antonio
Published in Chemistry : a European journal (09.01.2012)
Published in Chemistry : a European journal (09.01.2012)
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Journal Article
Design, Synthesis, Evaluation, and Structure of VitaminD Analogues with Furan Side Chains
Fraga, Ramón, Zacconi, Flavia, Sussman, Fredy, Ordonez-Moran, Paloma, Munoz, Alberto, Huet, Tiphaine, Molnar, Ferdinand, Moras, Dino, Rochel, Natacha, Maestro, Miguel, Mourino, Antonio
Published in Chemistry : a European journal (09.01.2012)
Published in Chemistry : a European journal (09.01.2012)
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Journal Article
Structural views on the steroid receptor RNA activator
Thore, Stéphane, Arieti, Fabiana, Huet, Tiphaine, Gabus-Darlix, Caroline
Published in Acta crystallographica. Section A, Foundations of crystallography (25.08.2013)
Published in Acta crystallographica. Section A, Foundations of crystallography (25.08.2013)
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Structure-Function Relationships and Crystal Structures of the Vitamin D Receptor Bound 2α-Methyl-(20S,23S)- and 2α-Methyl-(20S,23R)-epoxymethano-1α,2S-dihydroxyvitamin D3
ANTONY, Pierre, SIGÜEIRO, Rita, HUET, Tiphaine, SATO, Yoshiteru, RAMALANJAONA, Nick, CEZAR RODRIGUES, Luis, MOURINO, Antonio, MORAS, Dino, ROCHEL, Natacha
Published in Journal of medicinal chemistry (2010)
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Published in Journal of medicinal chemistry (2010)
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