Comparison of Polysorbate 80 Hydrolysis and Oxidation on the Aggregation of a Monoclonal Antibody
Larson, Nicholas R., Wei, Yangjie, Prajapati, Indira, Chakraborty, Aishik, Peters, Bjorn, Kalonia, Cavan, Hudak, Suzanne, Choudhary, Sureshkumar, Esfandiary, Reza, Dhar, Prajna, Schöneich, Christian, Middaugh, C. Russell
Published in Journal of pharmaceutical sciences (01.01.2020)
Published in Journal of pharmaceutical sciences (01.01.2020)
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Effects of antibody disulfide bond reduction on purification process performance and final drug substance stability
Chung, Wai Keen, Russell, Brian, Yang, Yanhong, Handlogten, Michael, Hudak, Suzanne, Cao, Mingyan, Wang, Jihong, Robbins, David, Ahuja, Sanjeev, Zhu, Min
Published in Biotechnology and bioengineering (01.06.2017)
Published in Biotechnology and bioengineering (01.06.2017)
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Visible Light Degradation of a Monoclonal Antibody in a High-Concentration Formulation: Characterization of a Tryptophan-Derived Chromophoric Photo-product by Comparison to Photo-degradation of N‑Acetyl‑l‑tryptophan Amide
Prajapati, Indira, Larson, Nicholas R, Choudhary, Sureshkumar, Kalonia, Cavan, Hudak, Suzanne, Esfandiary, Reza, Middaugh, C. Russell, Schöneich, Christian
Published in Molecular pharmaceutics (06.09.2021)
Published in Molecular pharmaceutics (06.09.2021)
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Cis/Trans Isomerization of Unsaturated Fatty Acids in Polysorbate 80 During Light Exposure of a Monoclonal Antibody–Containing Formulation
Prajapati, Indira, Peters, Björn-Hendrik, Larson, Nicholas R., Wei, Yangjie, Choudhary, Sureshkumar, Kalonia, Cavan, Hudak, Suzanne, Esfandiary, Reza, Middaugh, C. Russell, Schöneich, Christian
Published in Journal of pharmaceutical sciences (01.01.2020)
Published in Journal of pharmaceutical sciences (01.01.2020)
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A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding
Douthwaite, Julie, Moisan, Jacques, Privezentzev, Cyril, Soskic, Blagoje, Sabbah, Shereen, Cohen, Suzanne, Collinson, Andie, England, Elizabeth, Huntington, Catherine, Kemp, Ben, Zhuang, Li, Hudak, Suzanne, Rees, D Gareth, Goldberg, Debbie, Barton, Chris, Chang, Linda, Vainshtein, Inna, Liang, Meina, Iciek, Laurie, Ambery, Philip, Peakman, Mark, Vaughan, Tristan J, Tree, Tim I M, Sansom, David M, Bowen, Michael A, Minter, Ralph R, Jermutus, Lutz
Published in The Journal of immunology (1950) (01.01.2017)
Published in The Journal of immunology (1950) (01.01.2017)
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Correction: A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding
Douthwaite, Julie, Moisan, Jacques, Privezentzev, Cyril, Soskic, Blagoje, Sabbah, Shereen, Cohen, Suzanne, Collinson, Andie, England, Elizabeth, Huntington, Catherine, Kemp, Ben, Zhuang, Li, Hudak, Suzanne, Rees, D Gareth, Goldberg, Debbie, Barton, Chris, Chang, Linda, Vainshtein, Inna, Liang, Meina, Iciek, Laurie, Ambery, Philip, Peakman, Mark, Vaughan, Tristan J, Tree, Tim I M, Sansom, David M, Bowen, Michael A, Minter, Ralph R, Jermutus, Lutz
Published in The Journal of immunology (1950) (01.09.2017)
Published in The Journal of immunology (1950) (01.09.2017)
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PREVENTION OF PROTEIN DISULFIDE BOND REDUCTION
HANDLOGTEN, Michael, CHUNG, Wai Keen, ZHU, Min, HWANG, Kenneth, WANG, Jihong, NARANG, Someet, RUSSELL, Brian, HUDAK, Suzanne, GOLDBERG, Deborah Sweet, AHUJA, Sanjeev
Year of Publication 31.03.2022
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Year of Publication 31.03.2022
Patent
Prevention of protein disulfide bond reduction
Zhu, Min, Chung, Wai Keen, Handlogten, Michael, Narang, Someet, Hwang, Kenneth, Wang, Jihong, Russell, Brian, Goldberg, Deborah Sweet, Hudak, Suzanne, Ahuja, Sanjeev
Year of Publication 30.04.2020
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Year of Publication 30.04.2020
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PREVENTION OF PROTEIN DISULFIDE BOND REDUCTION
CHUNG, Wai, Keen, HANDLOGTEN, Michael, ZHU, Min, HWANG, Kenneth, WANG, Jihong, NARANG, Someet, RUSSELL, Brian, HUDAK, Suzanne, GOLDBERG, Deborah, Sweet, AHUJA, Sanjeev
Year of Publication 15.01.2020
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Year of Publication 15.01.2020
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PREVENTION OF PROTEIN DISULFIDE BOND REDUCTION
HANDLOGTEN, Michael, CHUNG, Wai Keen, ZHU, Min, HWANG, Kenneth, WANG, Jihong, NARANG, Someet, RUSSELL, Brian, HUDAK, Suzanne, GOLDBERG, Deborah Sweet, AHUJA, Sanjeev
Year of Publication 18.04.2019
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Year of Publication 18.04.2019
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PREVENTION OF PROTEIN DISULFIDE BOND REDUCTION
CHUNG, Wai, Keen, HANDLOGTEN, Michael, ZHU, Min, HWANG, Kenneth, WANG, Jihong, NARANG, Someet, RUSSELL, Brian, HUDAK, Suzanne, GOLDBERG, Deborah, Sweet, AHUJA, Sanjeev
Year of Publication 20.03.2019
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Year of Publication 20.03.2019
Patent
Prevention of protein disulfide bond reduction
Zhu, Min, Chung, Wai Keen, Handlogten, Michael, Narang, Someet, Hwang, Kenneth, Wang, Jihong, Russell, Brian, Goldberg, Deborah Sweet, Hudak, Suzanne, Ahuja, Sanjeev
Year of Publication 13.12.2018
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Year of Publication 13.12.2018
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PREVENTION OF PROTEIN DISULFIDE BOND REDUCTION
CHUNG, Wai, Keen, HANDLOGTEN, Michael, ZHU, Min, HWANG, Kenneth, WANG, Jihong, NARANG, Someet, RUSSELL, Brian, HUDAK, Suzanne, GOLDBERG, Deborah, Sweet, AHUJA, Sanjeev
Year of Publication 16.11.2017
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Year of Publication 16.11.2017
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PREVENTION OF PROTEIN DISULFIDE BOND REDUCTION
NARANG, SOMEET, HUDAK, SUZANNE, AHUJA, SANJEEV, RUSSELL, BRIAN, ZHU, MIN, GOLDBERG, DEBORAH SWEET, HANDLOGTEN, MICHAEL, CHUNG, WAI KEEN, HWANG, KENNETH, WANG, JIHONG
Year of Publication 16.11.2017
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Year of Publication 16.11.2017
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PREVENTION OF PROTEIN DISULFIDE BOND REDUCTION
GOLDBERG DEBORAH SWEET, AHUJA SANJEEV, WANG JIHONG, HUDAK SUZANNE, CHUNG WAI KEEN, HANDLOGTEN MICHAEL, HWANG KENNETH, RUSSELL BRIAN, NARANG SOMEET, ZHU MIN
Year of Publication 01.03.2019
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Year of Publication 01.03.2019
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