Serine 776 of Ataxin-1 Is Critical for Polyglutamine-Induced Disease in SCA1 Transgenic Mice
Emamian, Effat S., Kaytor, Michael D., Duvick, Lisa A., Zu, Tao, Tousey, Susan K., Zoghbi, Huda Y., Clark, H.Brent, Orr, Harry T.
Published in Neuron (Cambridge, Mass.) (08.05.2003)
Published in Neuron (Cambridge, Mass.) (08.05.2003)
Get full text
Journal Article
insulin-like growth factor pathway is altered in spinocerebellar ataxia type 1 and type 7
Gatchel, Jennifer R, Watase, Kei, Thaller, Christina, Carson, James P, Jafar-Nejad, Paymaan, Shaw, Chad, Zu, Tao, Orr, Harry T, Zoghbi, Huda Y
Published in Proceedings of the National Academy of Sciences - PNAS (29.01.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (29.01.2008)
Get full text
Journal Article
Epigenetics and Human Disease
Zoghbi, Huda Y, Beaudet, Arthur L
Published in Cold Spring Harbor perspectives in biology (01.02.2016)
Published in Cold Spring Harbor perspectives in biology (01.02.2016)
Get full text
Journal Article
Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1
Nitschke, Larissa, Coffin, Stephanie L, Xhako, Eder, El-Najjar, Dany B, Orengo, James P, Alcala, Elizabeth, Dai, Yanwan, Wan, Ying-Wooi, Liu, Zhandong, Orr, Harry T, Zoghbi, Huda Y
Published in JCI insight (08.02.2021)
Published in JCI insight (08.02.2021)
Get full text
Journal Article
Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction
Helmlinger, Dominique, Hardy, Sara, Abou-Sleymane, Gretta, Eberlin, Adrien, Bowman, Aaron B, Gansmüller, Anne, Picaud, Serge, Zoghbi, Huda Y, Trottier, Yvon, Tora, Làszlò, Devys, Didier
Published in PLoS biology (01.03.2006)
Published in PLoS biology (01.03.2006)
Get full text
Journal Article
Increased Axonal Bouton Stability during Learning in the Mouse Model of MECP2 Duplication Syndrome
Ash, Ryan T, Fahey, Paul G, Park, Jiyoung, Zoghbi, Huda Y, Smirnakis, Stelios M
Published in eNeuro (01.05.2018)
Published in eNeuro (01.05.2018)
Get full text
Journal Article
Pharmacometabolomic signature of ataxia SCA1 mouse model and lithium effects
Perroud, Bertrand, Jafar-Nejad, Paymaan, Wikoff, William R, Gatchel, Jennifer R, Wang, Lu, Barupal, Dinesh K, Crespo-Barreto, Juan, Fiehn, Oliver, Zoghbi, Huda Y, Kaddurah-Daouk, Rima
Published in PloS one (02.08.2013)
Published in PloS one (02.08.2013)
Get full text
Journal Article
Math1: An Essential Gene for the Generation of Inner Ear Hair Cells
Bermingham, Nessan A., Hassan, Bassem A., Price, Steven D., Vollrath, Melissa A., Ben-Arie, Nissim, Eatock, Ruth Anne, Bellen, Hugo J., Lysakowski, Anna, Zoghbi, Huda Y.
Published in Science (American Association for the Advancement of Science) (11.06.1999)
Published in Science (American Association for the Advancement of Science) (11.06.1999)
Get full text
Journal Article
yin and yang of MeCP2 phosphorylation
Chao, Hsiao-Tuan, Zoghbi, Huda Y
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2009)
Get full text
Journal Article
Polyglutamine expansion down-regulates specific neuronal genes before pathologic changes in SCA1
Zoghbi, Huda Y, Lin, Xi, Antalffy, Barbara, Kang, Dongcheul, Orr, Harry T
Published in Nature neuroscience (01.02.2000)
Published in Nature neuroscience (01.02.2000)
Get full text
Journal Article
A Long CAG Repeat in the Mouse Sca1 Locus Replicates SCA1 Features and Reveals the Impact of Protein Solubility on Selective Neurodegeneration
Watase, Kei, Weeber, Edwin J., Xu, Bisong, Antalffy, Barbara, Yuva-Paylor, Lisa, Hashimoto, Kouichi, Kano, Masanobu, Atkinson, Richard, Sun, Yaling, Armstrong, Dawna L., Sweatt, J.David, Orr, Harry T., Paylor, Richard, Zoghbi, Huda Y.
Published in Neuron (Cambridge, Mass.) (13.06.2002)
Published in Neuron (Cambridge, Mass.) (13.06.2002)
Get full text
Journal Article
dAtaxin-2 mediates expanded Ataxin-1-induced neurodegeneration in a Drosophila model of SCA1
Al-Ramahi, Ismael, Pérez, Alma M, Lim, Janghoo, Zhang, Minghang, Sorensen, Rie, de Haro, Maria, Branco, Joana, Pulst, Stefan M, Zoghbi, Huda Y, Botas, Juan
Published in PLoS genetics (01.12.2007)
Published in PLoS genetics (01.12.2007)
Get full text
Journal Article
Neurodegeneration: From cellular concepts to clinical applications
Katsnelson, Alla, De Strooper, Bart, Zoghbi, Huda Y
Published in Science translational medicine (09.11.2016)
Published in Science translational medicine (09.11.2016)
Get more information
Journal Article
Mutation of the E6-AP Ubiquitin Ligase Reduces Nuclear Inclusion Frequency While Accelerating Polyglutamine-Induced Pathology in SCA1 Mice
Cummings, Christopher J, Reinstein, Eyal, Sun, Yaling, Antalffy, Barbara, Jiang, Yong-hui, Ciechanover, Aaron, Orr, Harry T, Beaudet, Arthur L, Zoghbi, Huda Y
Published in Neuron (Cambridge, Mass.) (01.12.1999)
Published in Neuron (Cambridge, Mass.) (01.12.1999)
Get full text
Journal Article
The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival
Wallis, Deeann, Hamblen, Melanie, Zhou, Yi, Venken, Koen J T., Schumacher, Armin, Grimes, H. Leighton, Zoghbi, Huda Y., Orkin, Stuart H., Bellen, Hugo J.
Published in Development (Cambridge) (01.01.2003)
Published in Development (Cambridge) (01.01.2003)
Get full text
Journal Article