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Chen, Yi-Fong, Lawal, Bashir, Huang, Li-Jiau, Kuo, Sheng-Chu, Sumitra, Maryam Rachmawati, Mokgautsi, Ntlotlang, Lin, Hung-Yun, Huang, Hsu-Shan
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Design, Synthesis, and Preclinical Evaluation of New 5,6- (or 6,7-) Disubstituted-2-(fluorophenyl)quinolin-4-one Derivatives as Potent Antitumor Agents
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Synthesis and SAR studies of novel 6,7,8‐substituted 4‐substituted benzyloxyquinolin‐2(1H)‐one derivatives for anticancer activity
Chen, Yi‐Fong, Lin, Yi‐Chien, Morris‐Natschke, Susan L, Wei, Chen‐Fang, Shen, Ting‐Chen, Lin, Hui‐Yi, Hsu, Mei‐Hua, Chou, Li‐Chen, Zhao, Yu, Kuo, Sheng‐Chu, Lee, Kuo‐Hsiung, Huang, Li‐Jiau
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Ginger and Its Bioactive Component Inhibit Enterotoxigenic Escherichia coli Heat-Labile Enterotoxin-Induced Diarrhea in Mice
Chen, Jaw-Chyun, Huang, Li-Jiau, Wu, Shih-Lu, Kuo, Sheng-Chu, Ho, Tin-Yun, Hsiang, Chien-Yun
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Three new clerodane diterpenes from Polyalthia longifolia var. pendula
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Published in Molecules (Basel, Switzerland) (13.02.2014)
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The anti‐inflammatory carbazole, LCY‐2‐CHO, inhibits lipopolysaccharide‐induced inflammatory mediator expression through inhibition of the p38 mitogen‐activated protein kinase signaling pathway in macrophages
Ho, Feng‐Ming, Lai, Chih‐Chang, Huang, Li‐Jiau, Kuo, Tsun Cheng, Chao, Chien M, Lin, Wan‐Wan
Published in British journal of pharmacology (01.03.2004)
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Novel quinolone CHM-1 induces apoptosis and inhibits metastasis in a human osterogenic sarcoma cell line
Hsu, Shu-Chun, Yang, Jai-Sing, Kuo, Chao-Lin, Lo, Chyi, Lin, Jing-Pin, Hsia, Te-Chun, Lin, Jen-Jyh, Lai, Kuang-Chi, Kuo, Hsiu-Maan, Huang, Li-Jiau, Kuo, Sheng-Chu, Wood, W. Gibson, Chung, Jing-Gung
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synthesized 2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-one (CHM-1) promoted G2/M arrest through inhibition of CDK1 and induced apoptosis through the mitochondrial-dependent pathway in CT-26 murine colorectal adenocarcinoma cells
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Published in Journal of gastroenterology (01.10.2009)
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Anticancer mechanisms of YC-1 in human lung cancer cell line, NCI-H226
Chen, Chun-Jen, Hsu, Mei-Hua, Huang, Li-Jiau, Yamori, Takao, Chung, Jing-Gung, Lee, Fang-Yu, Teng, Che-Ming, Kuo, Sheng-Chu
Published in Biochemical pharmacology (15.01.2008)
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Inhibition of nitric oxide production by the carbazole compound LCY-2-CHO via blockade of activator protein-1 and CCAAT/enhancer-binding protein activation in microglia
Chang, Ling-Chu, Tsao, Lo-Ti, Chang, Chi-Sen, Chen, Chun-Jung, Huang, Li-Jiau, Kuo, Sheng-Chu, Lin, Ruey-Hseng, Wang, Jih-Pyang
Published in Biochemical pharmacology (15.08.2008)
Published in Biochemical pharmacology (15.08.2008)
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Proteomic approach to studying the cytotoxicity of YC-1 on U937 leukemia cells and antileukemia activity in orthotopic model of leukemia mice
Chung, Jing-Gung, Yang, Jai-Sing, Huang, Li-Jiau, Lee, Fang-Yu, Teng, Che-Ming, Tsai, Sheng-Chung, Lin, Kuei-Li, Wang, Shu-Fang, Kuo, Sheng-Chu
Published in Proteomics (Weinheim) (01.09.2007)
Published in Proteomics (Weinheim) (01.09.2007)
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Signaling mechanisms of inhibition of phospholipase D activation by CHS-111 in formyl peptide-stimulated neutrophils
Chang, Ling-Chu, Huang, Tai-Hung, Chang, Chi-Sen, Tsai, Ya-Ru, Lin, Ruey-Hseng, Lee, Pin-Wen, Hsu, Mei-Feng, Huang, Li-Jiau, Wang, Jih-Pyang
Published in Biochemical pharmacology (15.01.2011)
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Neuroprotective Effects of Ugonin K on Hydrogen Peroxide-Induced Cell Death in Human Neuroblastoma SH-SY5Y Cells
Lin, Yi-Chien, Huang, Yaun-Chao, Chen, Sheng-Chih, Liaw, Chih-Chuang, Kuo, Sheng-Chu, Huang, Li-Jiau, Gean, Po-Wu
Published in Neurochemical research (01.05.2009)
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Mechanistic studies on regioselective dephosphorylation of phosphate prodrugs during a facile synthesis of antitumor phosphorylated 2-phenyl-6,7-methylenedioxy-1H-quinolin-4-one
Cheng, Yung-Yi, Liu, Chin-Yu, Huang, Li-Jiau, Huang, Chi-Hung, Lee, Kuo-Hsiung, Lin, Cheng-Tung, Kuo, Sheng-Chu
Published in Molecules (Basel, Switzerland) (08.07.2013)
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Synthesis and antiplatelet activity of ethyl 4-(1-benzyl-1 H-indazol-3-yl)benzoate (YD-3) derivatives
Chen, Hua-Sin, Kuo, Sheng-Chu, Teng, Che-Ming, Lee, Fang-Yu, Wang, Jih-Pyang, Lee, Yu-Chun, Kuo, Chiung-Wen, Huang, Ching-Che, Wu, Chin-Chung, Huang, Li-Jiau
Published in Bioorganic & medicinal chemistry (01.02.2008)
Published in Bioorganic & medicinal chemistry (01.02.2008)
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Geraniin-mediated apoptosis by cleavage of focal adhesion kinase through up-regulation of Fas ligand expression in human melanoma cells
Lee, Jang-Chang, Tsai, Chih-Yen, Kao, Jung-Yie, Kao, Ming-Ching, Tsai, Shih-Chang, Chang, Chih-Shiang, Huang, Li-Jiau, Kuo, Sheng-Chu, Lin, Jen-Kun, Way, Tzong-Der
Published in Molecular nutrition & food research (01.06.2008)
Published in Molecular nutrition & food research (01.06.2008)
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Synthesis and biological relationships of 3′,6-substituted 2-phenyl-4-quinolone-3-carboxylic acid derivatives as antimitotic agents
Lai, Ya-Yun, Huang, Li-Jiau, Lee, Kuo-Hsiung, Xiao, Zhiyan, Bastow, Kenneth F., Yamori, Takao, Kuo, Sheng-Chu
Published in Bioorganic & medicinal chemistry (03.01.2005)
Published in Bioorganic & medicinal chemistry (03.01.2005)
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