Small‐Molecule Inhibitors of METTL3, the Major Human Epitranscriptomic Writer
Bedi, Rajiv K., Huang, Danzhi, Eberle, Stefanie A., Wiedmer, Lars, Śledź, Pawel, Caflisch, Amedeo
Published in ChemMedChem (06.05.2020)
Published in ChemMedChem (06.05.2020)
Get full text
Journal Article
METTL3 Inhibitors for Epitranscriptomic Modulation of Cellular Processes
Moroz‐Omori, Elena V., Huang, Danzhi, Kumar Bedi, Rajiv, Cheriyamkunnel, Sherry J., Bochenkova, Elena, Dolbois, Aymeric, Rzeczkowski, Maciej D., Li, Yaozong, Wiedmer, Lars, Caflisch, Amedeo
Published in ChemMedChem (06.10.2021)
Published in ChemMedChem (06.10.2021)
Get full text
Journal Article
Kinase selectivity potential for inhibitors targeting the ATP binding site: a network analysis
Huang, Danzhi, Zhou, Ting, Lafleur, Karine, Nevado, Cristina, Caflisch, Amedeo
Published in Bioinformatics (15.01.2010)
Published in Bioinformatics (15.01.2010)
Get full text
Journal Article
Quantum mechanical methods for drug design
Zhou, Ting, Huang, Danzhi, Caflisch, Amedeo
Published in Current topics in medicinal chemistry (2010)
Published in Current topics in medicinal chemistry (2010)
Get more information
Journal Article
The catalytic mechanism of the RNA methyltransferase METTL3
Corbeski, Ivan, Vargas-Rosales, Pablo Andrés, Bedi, Rajiv Kumar, Deng, Jiahua, Coelho, Dylan, Braud, Emmanuelle, Iannazzo, Laura, Li, Yaozong, Huang, Danzhi, Ethève-Quelquejeu, Mélanie, Cui, Qiang, Caflisch, Amedeo
Published in eLife (12.03.2024)
Published in eLife (12.03.2024)
Get full text
Journal Article
Structure-Based Optimization of Potent and Selective Inhibitors of the Tyrosine Kinase Erythropoietin Producing Human Hepatocellular Carcinoma Receptor B4 (EphB4)
Lafleur, Karine, Huang, Danzhi, Zhou, Ting, Caflisch, Amedeo, Nevado, Cristina
Published in Journal of medicinal chemistry (22.10.2009)
Published in Journal of medicinal chemistry (22.10.2009)
Get full text
Journal Article
Structure-based drug design identifies polythiophenes as antiprion compounds
Herrmann, Uli S, Schütz, Anne K, Shirani, Hamid, Huang, Danzhi, Saban, Dino, Nuvolone, Mario, Li, Bei, Ballmer, Boris, Åslund, Andreas K O, Mason, Jeffrey J, Rushing, Elisabeth, Budka, Herbert, Nyström, Sofie, Hammarström, Per, Böckmann, Anja, Caflisch, Amedeo, Meier, Beat H, Nilsson, K Peter R, Hornemann, Simone, Aguzzi, Adriano
Published in Science translational medicine (05.08.2015)
Published in Science translational medicine (05.08.2015)
Get more information
Journal Article
Is Quantum Mechanics Necessary for Predicting Binding Free Energy?
Zhou, Ting, Huang, Danzhi, Caflisch, Amedeo
Published in Journal of medicinal chemistry (24.07.2008)
Published in Journal of medicinal chemistry (24.07.2008)
Get full text
Journal Article
Flaviviral Protease Inhibitors Identified by Fragment-Based Library Docking into a Structure Generated by Molecular Dynamics
Ekonomiuk, Dariusz, Su, Xun-Cheng, Ozawa, Kiyoshi, Bodenreider, Christophe, Lim, Siew Pheng, Otting, Gottfried, Huang, Danzhi, Caflisch, Amedeo
Published in Journal of medicinal chemistry (13.08.2009)
Published in Journal of medicinal chemistry (13.08.2009)
Get full text
Journal Article
Structure-based design of ligands of the m6A-RNA reader YTHDC1
Li, Yaozong, Bedi, Rajiv Kumar, Nai, Francesco, von Roten, Valentin, Dolbois, Aymeric, Zálešák, František, Nachawati, Raed, Huang, Danzhi, Caflisch, Amedeo
Published in European journal of medicinal chemistry reports (01.08.2022)
Published in European journal of medicinal chemistry reports (01.08.2022)
Get full text
Journal Article
Discovery of Cell-Permeable Non-Peptide Inhibitors of β-Secretase by High-Throughput Docking and Continuum Electrostatics Calculations
Huang, Danzhi, Lüthi, Urs, Kolb, Peter, Edler, Karin, Cecchini, Marco, Audetat, Stephan, Barberis, Alcide, Caflisch, Amedeo
Published in Journal of medicinal chemistry (11.08.2005)
Published in Journal of medicinal chemistry (11.08.2005)
Get full text
Journal Article
Discovery of a non-peptidic inhibitor of west nile virus NS3 protease by high-throughput docking
Ekonomiuk, Dariusz, Su, Xun-Cheng, Ozawa, Kiyoshi, Bodenreider, Christophe, Lim, Siew Pheng, Yin, Zheng, Keller, Thomas H, Beer, David, Patel, Viral, Otting, Gottfried, Caflisch, Amedeo, Huang, Danzhi
Published in PLoS neglected tropical diseases (01.01.2009)
Published in PLoS neglected tropical diseases (01.01.2009)
Get full text
Journal Article