Small molecule and macrocyclic pyrazole derived inhibitors of myeloperoxidase (MPO)
Hu, Carol H., Neissel Valente, Meriah W., Halpern, O. Scott, Jusuf, Sutjano, Khan, Javed A., Locke, Gregory A., Duke, Gerald J., Liu, Xiaoqin, Duclos, Franck J., Wexler, Ruth R., Kick, Ellen K., Smallheer, Joanne M.
Published in Bioorganic & medicinal chemistry letters (15.06.2021)
Published in Bioorganic & medicinal chemistry letters (15.06.2021)
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Journal Article
Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors
Hu, Carol H., Wang, Tammy C., Qiao, Jennifer X., Haque, Lauren, Chen, Alice Y.A., Taylor, David S., Ying, Xiaohong, Onorato, Joelle M., Galella, Michael, Shen, Hong, Huang, Christine S., Toussaint, Nathalie, Li, Yi-Xin, Abell, Lynn, Adam, Leonard P., Gordon, David, Wexler, Ruth R., Finlay, Heather J.
Published in Bioorganic & medicinal chemistry letters (15.12.2018)
Published in Bioorganic & medicinal chemistry letters (15.12.2018)
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Journal Article
2-Amino-1,3,4-thiadiazoles in the 7-hydroxy-N-neopentyl spiropiperidine indolinyl series as potent P2Y1 receptor antagonists
Hu, Carol H., Qiao, Jennifer X., Han, Ying, Wang, Tammy C., Hua, Ji, Price, Laura A., Wu, Qimin, Shen, Hong, Huang, Christine S., Rehfuss, Robert, Wexler, Ruth R., Lam, Patrick Y.S.
Published in Bioorganic & medicinal chemistry letters (01.06.2014)
Published in Bioorganic & medicinal chemistry letters (01.06.2014)
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Journal Article
4-Benzothiazole-7-hydroxyindolinyl Diaryl Ureas Are Potent P2Y1 Antagonists with Favorable Pharmacokinetics: Low Clearance and Small Volume of Distribution
Qiao, Jennifer X., Wang, Tammy C., Hiebert, Sheldon, Hu, Carol H., Schumacher, William A., Spronk, Steven A., Clark, Charles G., Han, Ying, Hua, Ji, Price, Laura A., Shen, Hong, Chacko, Silvi A., Everlof, Gerry, Bostwick, Jeffrey S., Steinbacher, Thomas E., Li, Yi-Xin, Huang, Christine S., Seiffert, Dietmar A., Rehfuss, Robert, Wexler, Ruth R., Lam, Patrick Y. S.
Published in ChemMedChem (01.10.2014)
Published in ChemMedChem (01.10.2014)
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Journal Article
Investigation of a Clostridium difficile cluster by multilocus sequence typing in a bone marrow transplant unit
Hu, Carol, MD, Sunday, Richard, MS, Bruminhent, Jackrapong, MD, Bobik, Brent, BS, Wagner, John, MD, Weiss, Mark, MD, Flomenberg, Phyllis, MD, Wang, Zi-Xuan, PhD
Published in American journal of infection control (01.06.2014)
Published in American journal of infection control (01.06.2014)
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Journal Article
2-Amino-1,3,4-thiadiazoles in the 7-hydroxy-N-neopentyl spiropiperidine indolinyl series as potent P2Y(1) receptor antagonists
Hu, Carol H., Qiao, Jennifer X., Han, Ying, Wang, Tammy C., Hua, Ji, Price, Laura A., Wu, Qimin, Shen, Hong, Huang, Christine S., Rehfuss, Robert, Wexler, Ruth R., Lam, Patrick Y. S.
Published in Bioorganic & medicinal chemistry letters (01.06.2014)
Published in Bioorganic & medicinal chemistry letters (01.06.2014)
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Journal Article
2-Amino-1,3,4-thiadiazoles in the 7-hydroxy-N-neopentyl spiropiperidine indolinyl series as potent P2Y sub(1) receptor antagonists
Hu, Carol H, Qiao, Jennifer X, Han, Ying, Wang, Tammy C, Hua, Ji, Price, Laura A, Wu, Qimin, Shen, Hong, Huang, Christine S, Rehfuss, Robert, Wexler, Ruth R, Lam, Patrick YS
Published in Bioorganic & medicinal chemistry letters (01.06.2014)
Published in Bioorganic & medicinal chemistry letters (01.06.2014)
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Journal Article
4-Benzothiazole-7-hydroxyindolinyl Diaryl Ureas Are Potent P2Y(1) Antagonists with Favorable Pharmacokinetics: Low Clearance and Small Volume of Distribution
Qiao, Jennifer X., Wang, Tammy C., Hiebert, Sheldon, Hu, Carol H., Schumacher, William A., Spronk, Steven A., Clark, Charles G., Han, Ying, Hua, Ji, Price, Laura A., Shen, Hong, Chacko, Silvi A., Everlof, Gerry, Bostwick, Jeffrey S., Steinbacher, Thomas E., Li, Yi-Xin, Huang, Christine S., Seiffert, Dietmar A., Rehfuss, Robert, Wexler, Ruth R., Lam, Patrick Y. S.
Published in ChemMedChem (01.10.2014)
Published in ChemMedChem (01.10.2014)
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Journal Article
Acute Perforated Appendicitis Secondary to Sarcoidosis
POLICHA, Aleksandra, HU, Carol, HOLMES, Phoebe, COHN, John R, MARTIN, Niels D
Published in The American surgeon (01.05.2012)
Published in The American surgeon (01.05.2012)
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Journal Article
4‐Benzothiazole‐7‐hydroxyindolinyl Diaryl Ureas Are Potent P2Y 1 Antagonists with Favorable Pharmacokinetics: Low Clearance and Small Volume of Distribution
Qiao, Jennifer X., Wang, Tammy C., Hiebert, Sheldon, Hu, Carol H., Schumacher, William A., Spronk, Steven A., Clark, Charles G., Han, Ying, Hua, Ji, Price, Laura A., Shen, Hong, Chacko, Silvi A., Everlof, Gerry, Bostwick, Jeffrey S., Steinbacher, Thomas E., Li, Yi‐Xin, Huang, Christine S., Seiffert, Dietmar A., Rehfuss, Robert, Wexler, Ruth R., Lam, Patrick Y. S.
Published in ChemMedChem (01.10.2014)
Published in ChemMedChem (01.10.2014)
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Journal Article
Clostridium Difficile Colonization and Disease in Patients Undergoing Hematopoietic Stem Cell Transplantation
Bruminhent, Jackrapong, Wang, Zi-Xuan, Hu, Carol, Wagner, John, Sunday, Richard, Bobik, Brent, Hegarty, Sarah, Keith, Scott, Alpdogan, Seyfettin, Carabasi, Matthew, Filicko-O’Hara, Joanne, Flomenberg, Neal, Kasner, Margaret, Outschoorn, Ubaldo Martinez, Weiss, Mark, Flomenberg, Phyllis
Published in Biology of blood and marrow transplantation (01.09.2014)
Published in Biology of blood and marrow transplantation (01.09.2014)
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Journal Article
Synthesis and Cardiac Imaging of 18F-Ligands Selective for β1-Adrenoreceptors
Radeke, Heike S, Purohit, Ajay, Harris, Thomas D, Hanson, Kelley, Jones, Reinaldo, Hu, Carol, Yalamanchili, Padmaja, Hayes, Megan, Yu, Ming, Guaraldi, Mary, Kagan, Mikhail, Azure, Michael, Cdebaca, Michael, Robinson, Simon, Casebier, David
Published in ACS medicinal chemistry letters (08.09.2011)
Published in ACS medicinal chemistry letters (08.09.2011)
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Journal Article
Synthesis and Cardiac Imaging of 18 F-Ligands Selective for β 1 -Adrenoreceptors
Radeke, Heike S., Purohit, Ajay, Harris, Thomas D., Hanson, Kelley, Jones, Reinaldo, Hu, Carol, Yalamanchili, Padmaja, Hayes, Megan, Yu, Ming, Guaraldi, Mary, Kagan, Mikhail, Azure, Michael, Cdebaca, Michael, Robinson, Simon, Casebier, David
Published in ACS medicinal chemistry letters (08.09.2011)
Published in ACS medicinal chemistry letters (08.09.2011)
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Journal Article
Synthesis and Cardiac Imaging of (18)F-Ligands Selective for β1-Adrenoreceptors
Radeke, Heike S, Purohit, Ajay, Harris, Thomas D, Hanson, Kelley, Jones, Reinaldo, Hu, Carol, Yalamanchili, Padmaja, Hayes, Megan, Yu, Ming, Guaraldi, Mary, Kagan, Mikhail, Azure, Michael, Cdebaca, Michael, Robinson, Simon, Casebier, David
Published in ACS medicinal chemistry letters (08.09.2011)
Published in ACS medicinal chemistry letters (08.09.2011)
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Journal Article
Triazolopyridine inhibitors of myeloperoxidase
Shaw, Scott A, Vokits, Benjamin P, Smallheer, Joanne M, Hu, Carol Hui, Valente, Meriah Neissel, Halpern, Oz Scott
Year of Publication 13.07.2021
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Year of Publication 13.07.2021
Patent
Triazolopyridine inhibitors of myeloperoxidase
Shaw, Scott A, Kick, Ellen K, Smallheer, Joanne M, Hu, Carol Hui, Halpern, Oz Scott
Year of Publication 10.09.2019
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Year of Publication 10.09.2019
Patent
Macrocyclic inhibitors of myeloperoxidase
Kick, Ellen K, Jusuf, Sutjano, Smallheer, Joanne M, Hu, Carol Hui, Valente, Meriah Neissel, Halpern, Oz Scott
Year of Publication 03.03.2020
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Year of Publication 03.03.2020
Patent