Translational PK/PD and model‐informed development of JNJ‐67842125, a Fab reversal agent for JNJ‐64179375, a long‐acting thrombin inhibitor
Ayyar, Vivaswath S., Jaiprasart, Pharavee, Geist, Brian, Huang Devine, Zheng, Case, Martin, Hazra, Anasuya, Hsu, Chyi‐Hung, Chintala, Madhu, Wang, Weirong
Published in British journal of pharmacology (01.10.2021)
Published in British journal of pharmacology (01.10.2021)
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Population pharmacokinetics and exposure‐response modeling analyses of guselkumab in patients with psoriatic arthritis
Chen, Yang, Miao, Xin, Hsu, Chyi‐Hung, Zhuang, Yanli, Kollmeier, Alexa, Xu, Zhenhua, Zhou, Honghui, Sharma, Amarnath
Published in Clinical and translational science (01.03.2022)
Published in Clinical and translational science (01.03.2022)
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Dynamic population pharmacokinetic–pharmacodynamic modelling and simulation supports similar efficacy in glycosylated haemoglobin response with once or twice‐daily dosing of canagliflozin
Winter, Willem, Dunne, Adrian, Trixhe, Xavier Woot, Devineni, Damayanthi, Hsu, Chyi‐Hung, Pinheiro, Jose, Polidori, David
Published in British journal of clinical pharmacology (01.05.2017)
Published in British journal of clinical pharmacology (01.05.2017)
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Phase I Dose-Finding Study of Weekly Single-Agent Patupilone in Patients With Advanced Solid Tumors
RUBIN, Eric H, ROTHERMEL, John, TESFAYE, Fisseha, TIANLING CHEN, HUBERT, Martine, HO, Yu-Yun, HSU, Chyi-Hung, OZA, Amit M
Published in Journal of clinical oncology (20.12.2005)
Published in Journal of clinical oncology (20.12.2005)
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Pharmacokinetics of an Everolimus‐Cyclosporine Immunosuppressive Regimen Over the First 6 Months After Kidney Transplantation
Kovarik, John M., Kaplan, Bruce, Silva, Hélio Tedesco, Kahan, Barry D., Dantal, Jacques, McMahon, Louis, Berthier, Stephane, Hsu, Chyi‐Hung, Rordorf, Christiane
Published in American journal of transplantation (01.05.2003)
Published in American journal of transplantation (01.05.2003)
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Translational PK/PD and model-informed development of JNJ-67842125, a F ab reversal agent for JNJ-64179375, a long-acting thrombin inhibitor
Ayyar, Vivaswath S, Jaiprasart, Pharavee, Geist, Brian, Huang Devine, Zheng, Case, Martin, Hazra, Anasuya, Hsu, Chyi-Hung, Chintala, Madhu, Wang, Weirong
Published in British journal of pharmacology (01.10.2021)
Published in British journal of pharmacology (01.10.2021)
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Trial Design and Statistical Considerations on the Assessment of Pharmacodynamic Similarity
Zhu, Peijuan, Hsu, Chyi-Hung, Liao, Jason, Xu, Steven, Zhang, Liping, Zhou, Honghui
Published in The AAPS journal (01.05.2019)
Published in The AAPS journal (01.05.2019)
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Everolimus in de novo cardiac transplantation: pharmacokinetics, therapeutic range, and influence on cyclosporine exposure
Kovarik, John M, Eisen, Howard, Dorent, Richard, Mancini, Donna, Vigano, Mario, Rouilly, Marisel, Hsu, Chyi-Hung, Rordorf, Christiane
Published in The Journal of heart and lung transplantation (01.10.2003)
Published in The Journal of heart and lung transplantation (01.10.2003)
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FTY720, a novel immunomodulator in de novo kidney transplant patients: pharmacokinetics and exposure-response relationship
Skerjanec, Andrej, Tedesco, Helio, Neumayer, Hans-H, Cole, Edward, Budde, Klemens, Hsu, Chyi-Hung, Schmouder, Robert
Published in Journal of clinical pharmacology (01.11.2005)
Published in Journal of clinical pharmacology (01.11.2005)
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Application of Trial Simulation in the Design of a Prospective Study for Concentration-QTc Analysis in Support of a Thorough QT Study Waiver
Zhu, Peijuan, Hsu, Chyi-Hung, Hu, Chuanpu, Wong, Peggy, Sy, Sherwin K. B., Nandy, Partha, Zhou, Honghui
Published in The AAPS journal (02.08.2020)
Published in The AAPS journal (02.08.2020)
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Open-label phase 3 study of intravenous golimumab in patients with polyarticular juvenile idiopathic arthritis
Ruperto, Nicolino, Brunner, Hermine I, Pacheco-Tena, César, Louw, Ingrid, Vega-Cornejo, Gabriel, Spindler, Alberto J, Kingsbury, Daniel J, Schmeling, Heinrike, Borzutzky, Arturo, Cuttica, Rubén, Inman, C J, Malievskiy, Victor, Scott, Christiaan, Keltsev, Vladimir, Terreri, Maria Teresa, Viola, Diego Oscar, Xavier, Ricardo M, Fernandes, Taciana A Pedrosa, Velázquez, María del Rocío Maldonado, Henrickson, Michael, Clark, Michael B, Bensley, Karen A, Li, Xiaoming, Lo, Kim Hung, Leu, Jocelyn H, Hsu, Chyi-Hung, Hsia, Elizabeth C, Xu, Zhenhua, Martini, Alberto, Lovell, Daniel J
Published in Rheumatology (Oxford, England) (02.10.2021)
Published in Rheumatology (Oxford, England) (02.10.2021)
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The method of averaging applied to pharmacokinetic/pharmacodynamic indirect response models
Dunne, Adrian, de Winter, Willem, Hsu, Chyi-Hung, Mariam, Shiferaw, Neyens, Martine, Pinheiro, José, de Trixhe, Xavier Woot
Published in Journal of pharmacokinetics and pharmacodynamics (01.08.2015)
Published in Journal of pharmacokinetics and pharmacodynamics (01.08.2015)
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Innovative Approaches for Designing and Analyzing Adaptive Dose-Ranging Trials
Bornkamp, Björn, Bretz, Frank, Dmitrienko, Alex, Enas, Greg, Gaydos, Brenda, Hsu, Chyi-Hung, König, Franz, Krams, Michael, Liu, Qing, Neuenschwander, Beat, Parke, Tom, Pinheiro, José, Roy, Amit, Sax, Rick, Shen, Frank
Published in Journal of biopharmaceutical statistics (01.01.2007)
Published in Journal of biopharmaceutical statistics (01.01.2007)
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The pharmacokinetics and pharmacodynamics of zoledronic acid in cancer patients with varying degrees of renal function
Skerjanec, Andrej, Berenson, James, Hsu, ChyiHung, Major, Pierre, Miller, Jr, Wilson H, Ravera, Christina, Schran, Horst, Seaman, John, Waldmeier, Felix
Published in Journal of clinical pharmacology (01.02.2003)
Published in Journal of clinical pharmacology (01.02.2003)
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Importance of Early Phase Insulin Secretion to Intravenous Glucose Tolerance in Subjects with Type 2 Diabetes Mellitus
Kahn, Steven E, Montgomery, Brenda, Howell, William, Ligueros-Saylan, Monica, Hsu, Chyi-Hung, Devineni, Damayanthi, McLeod, James F, Horowitz, Ann, Foley, James E
Published in The journal of clinical endocrinology and metabolism (01.12.2001)
Published in The journal of clinical endocrinology and metabolism (01.12.2001)
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Importance of early phase insulin secretion to intravenous glucose tolerance in subjects with type 2 diabetes mellitus
KAHN, Steven E, MONTGOMERY, Brenda, HOWELL, William, LIGUEROS-SAYLAN, Monica, HSU, Chyi-Hung, DEVINENI, Damayanthi, MCLEOD, James F, HOROWITZ, Ann, FOLEY, James E
Published in The journal of clinical endocrinology and metabolism (01.12.2001)
Published in The journal of clinical endocrinology and metabolism (01.12.2001)
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Adaptive and Model-Based Dose-Ranging Trials: Quantitative Evaluation and Recommendations. White Paper of the PhRMA Working Group on Adaptive Dose-Ranging Studies
Pinheiro, José, Sax, Frederic, Antonijevic, Zoran, Bornkamp, Björn, Bretz, Frank, Chuang-Stein, Christy, Dragalin, Vladimir, Fardipour, Parvin, Gallo, Paul, Gillespie, William, Hsu, Chyi-Hung, Miller, Frank, Padmanabhan, S. Krishna, Patel, Nitin, Perevozskaya, Inna, Roy, Amit, Sanil, Ashish, Smith, Jonathan R.
Published in Statistics in biopharmaceutical research (01.11.2010)
Published in Statistics in biopharmaceutical research (01.11.2010)
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