A high-fat diet promotes depression-like behavior in mice by suppressing hypothalamic PKA signaling
Vagena, Eirini, Ryu, Jae Kyu, Baeza-Raja, Bernat, Walsh, Nicola M., Syme, Catriona, Day, Jonathan P., Houslay, Miles D., Baillie, George S.
Published in Translational psychiatry (10.05.2019)
Published in Translational psychiatry (10.05.2019)
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Journal Article
Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1
Havekes, Robbert, Park, Alan J, Tudor, Jennifer C, Luczak, Vincent G, Hansen, Rolf T, Ferri, Sarah L, Bruinenberg, Vibeke M, Poplawski, Shane G, Day, Jonathan P, Aton, Sara J, Radwańska, Kasia, Meerlo, Peter, Houslay, Miles D, Baillie, George S, Abel, Ted
Published in eLife (23.08.2016)
Published in eLife (23.08.2016)
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Journal Article
Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1
Penzes, Peter, Houslay, Miles D, Brandon, Nicholas J, Murdoch, Hannah, Hayashi-Takagi, Akiko, Dunlop, Allan J, Graziane, Nick, Sawa, Akira, Makino, Yuichi, Yan, Zhen, Ishizuka, Koko, Takaki, Manabu, Xie, Zhong, Srivastava, Deepak P, Kamiya, Atsushi, Seshadri, Anupamaa J, Seshadri, Saurav, Baraban, Jay M, Tomoda, Toshifumi
Published in Nature neuroscience (01.03.2010)
Published in Nature neuroscience (01.03.2010)
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Journal Article
Oxygen-Dependent Cleavage of the p75 Neurotrophin Receptor Triggers Stabilization of HIF-1α
Le Moan, Natacha, Houslay, Daniel M., Christian, Frank, Houslay, Miles D., Akassoglou, Katerina
Published in Molecular cell (04.11.2011)
Published in Molecular cell (04.11.2011)
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Journal Article
PKA phosphorylation of p62/SQSTM1 regulates PB1 domain interaction partner binding
Christian, Frank, Krause, Eberhard, Houslay, Miles D., Baillie, George S.
Published in Biochimica et biophysica acta (01.11.2014)
Published in Biochimica et biophysica acta (01.11.2014)
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Journal Article
Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit
Jaaro-Peled, Hanna, Kumar, Sunil, Hughes, Dalton, Sumitomo, Akiko, Kim, Sun-Hong, Zoubovsky, Sandra, Hirota-Tsuyada, Yuki, Zala, Diana, Bruyere, Julie, Katz, Brittany M., Huang, Beverly, Flores, Rafael, Narayan, Soumya, Hou, Zhipeng, Economides, Aris N., Hikida, Takatoshi, Wetsel, William C., Deisseroth, Karl, Mori, Susumu, Brandon, Nicholas J., Tanaka, Motomasa, Ishizuka, Koko, Houslay, Miles D., Saudou, Frédéric, Dzirasa, Kafui, Sawa, Akira, Tomoda, Toshifumi
Published in Molecular psychiatry (01.03.2022)
Published in Molecular psychiatry (01.03.2022)
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Journal Article
Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ
Perino, Alessia, Ghigo, Alessandra, Ferrero, Enrico, Morello, Fulvio, Santulli, Gaetano, Baillie, George S, Damilano, Federico, Dunlop, Allan J, Pawson, Catherine, Walser, Romy, Levi, Renzo, Altruda, Fiorella, Silengo, Lorenzo, Langeberg, Lorene K, Neubauer, Gitte, Heymans, Stephane, Lembo, Giuseppe, Wymann, Matthias P, Wetzker, Reinhard, Houslay, Miles D, Iaccarino, Guido, Scott, John D, Hirsch, Emilio
Published in Molecular cell (08.04.2011)
Published in Molecular cell (08.04.2011)
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Journal Article
The role of ventral striatal cAMP signaling in stress-induced behaviors
Plattner, Florian, Hayashi, Kanehiro, Hernández, Adan, Benavides, David R, Tassin, Tara C, Tan, Chunfeng, Day, Jonathan, Fina, Maggy W, Yuen, Eunice Y, Yan, Zhen, Goldberg, Matthew S, Nairn, Angus C, Greengard, Paul, Nestler, Eric J, Taussig, Ronald, Nishi, Akinori, Houslay, Miles D, Bibb, James A
Published in Nature neuroscience (01.08.2015)
Published in Nature neuroscience (01.08.2015)
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Journal Article
Protein Kinase A Type I and Type II Define Distinct Intracellular Signaling Compartments
Di Benedetto, Giulietta, Zoccarato, Anna, Lissandron, Valentina, Terrin, Anna, Li, Xiang, Houslay, Miles D, Baillie, George S, Zaccolo, Manuela
Published in Circulation research (10.10.2008)
Published in Circulation research (10.10.2008)
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Journal Article
Compartmentalized PDE4A5 Signaling Impairs Hippocampal Synaptic Plasticity and Long-Term Memory
Havekes, Robbert, Park, Alan J, Tolentino, Rosa E, Bruinenberg, Vibeke M, Tudor, Jennifer C, Lee, Yool, Hansen, Rolf T, Guercio, Leonardo A, Linton, Edward, Neves-Zaph, Susana R, Meerlo, Peter, Baillie, George S, Houslay, Miles D, Abel, Ted
Published in The Journal of neuroscience (24.08.2016)
Published in The Journal of neuroscience (24.08.2016)
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Journal Article
Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington's disease
Tanaka, Motomasa, Ishizuka, Koko, Nekooki-Machida, Yoko, Endo, Ryo, Takashima, Noriko, Sasaki, Hideyuki, Komi, Yusuke, Gathercole, Amy, Huston, Elaine, Ishii, Kazuhiro, Hui, Kelvin Kai-Wan, Kurosawa, Masaru, Kim, Sun-Hong, Nukina, Nobuyuki, Takimoto, Eiki, Houslay, Miles D, Sawa, Akira
Published in The Journal of clinical investigation (01.04.2017)
Published in The Journal of clinical investigation (01.04.2017)
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Journal Article
EPAC and PKA allow cAMP dual control over DNA-PK nuclear translocation
Huston, Elaine, Lynch, Martin J, Mohamed, Ahmed, Collins, Daniel M, Hill, Elaine V, MacLeod, Ruth, Krause, Eberhard, Baillie, George S, Houslay, Miles D
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.2008)
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Journal Article
Structures of the four subfamilies of phosphodiesterase-4 provide insight into the selectivity of their inhibitors
Wang, Huanchen, Peng, Ming-Sheng, Chen, Yi, Geng, Jie, Robinson, Howard, Houslay, Miles D, Cai, Jiwen, Ke, Hengming
Published in Biochemical journal (01.12.2007)
Published in Biochemical journal (01.12.2007)
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Journal Article
Isoform-Selective Susceptibility of DISC1/Phosphodiesterase-4 Complexes to Dissociation by Elevated Intracellular cAMP Levels
Murdoch, Hannah, Mackie, Shaun, Collins, Daniel M, Hill, Elaine V, Bolger, Graeme B, Klussmann, Enno, Porteous, David J, Millar, J. Kirsty, Houslay, Miles D
Published in The Journal of neuroscience (29.08.2007)
Published in The Journal of neuroscience (29.08.2007)
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Journal Article
p75 Neurotrophin Receptor Regulates Energy Balance in Obesity
Baeza-Raja, Bernat, Sachs, Benjamin D., Li, Pingping, Christian, Frank, Vagena, Eirini, Davalos, Dimitrios, Le Moan, Natacha, Ryu, Jae Kyu, Sikorski, Shoana L., Chan, Justin P., Scadeng, Miriam, Taylor, Susan S., Houslay, Miles D., Baillie, George S., Saltiel, Alan R., Olefsky, Jerrold M., Akassoglou, Katerina
Published in Cell reports (Cambridge) (12.01.2016)
Published in Cell reports (Cambridge) (12.01.2016)
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Journal Article
Fluorescence Resonance Energy Transfer–Based Analysis of cAMP Dynamics in Live Neonatal Rat Cardiac Myocytes Reveals Distinct Functions of Compartmentalized Phosphodiesterases
Mongillo, Marco, McSorley, Theresa, Evellin, Sandrine, Sood, Arvind, Lissandron, Valentina, Terrin, Anna, Huston, Elaine, Hannawacker, Annette, Lohse, Martin J, Pozzan, Tullio, Houslay, Miles D, Zaccolo, Manuela
Published in Circulation research (09.07.2004)
Published in Circulation research (09.07.2004)
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Journal Article
Phosphorylation of RACK1 on Tyrosine 52 by c-Abl Is Required for Insulin-like Growth Factor I-mediated Regulation of Focal Adhesion Kinase
Kiely, Patrick A., Baillie, George S., Barrett, Robert, Buckley, Deirdre A., Adams, David R., Houslay, Miles D., O'Connor, Rosemary
Published in The Journal of biological chemistry (24.07.2009)
Published in The Journal of biological chemistry (24.07.2009)
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Journal Article
Cyclic AMP Phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a Vascular Endothelial Cadherin (VE-Cad)-based Signaling Complex and Controls cAMP-mediated Vascular Permeability
Rampersad, Sarah N., Ovens, Jeffrey D., Huston, Elaine, Umana, M. Bibiana, Wilson, Lindsay S., Netherton, Stuart J., Lynch, Martin J., Baillie, George S., Houslay, Miles D., Maurice, Donald H.
Published in The Journal of biological chemistry (29.10.2010)
Published in The Journal of biological chemistry (29.10.2010)
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Journal Article
The RACK1 scaffold protein: a dynamic cog in cell response mechanisms
McCahill, Angela, Warwicker, Jim, Bolger, Graeme B, Houslay, Miles D, Yarwood, Stephen J
Published in Molecular pharmacology (01.12.2002)
Published in Molecular pharmacology (01.12.2002)
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