Ileocolonic-Targeted JAK Inhibitor: A Safer and More Effective Treatment for Inflammatory Bowel Disease
Yadav, Vipul, House, Aileen, Matiz, Silvia, McCoubrey, Laura E, Bettano, Kimberly A, Bhave, Leena, Wang, Meiyao, Fan, Peter, Zhou, Siqun, Woodhouse, Janice D, Poimenidou, Eirini, Dou, Liu, Basit, Abdul W, Moy, Lily Y, Saklatvala, Robert, Hegde, Laxminarayan G, Yu, Hongshi
Published in Pharmaceutics (01.11.2022)
Published in Pharmaceutics (01.11.2022)
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Journal Article
The in vitro and in vivo investigation of a novel small chamber dry powder inhalation delivery system for preclinical dosing to rats
Sellers, Shari, Horodnik, Walter, House, Aileen, Wylie, Jennifer, Mauser, Peter, Donovan, Brent
Published in Inhalation toxicology (10.11.2015)
Published in Inhalation toxicology (10.11.2015)
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Journal Article
Inhaled formulation and device selection: bridging the gap between preclinical species and first-in-human studies
Wylie, Jennifer L, House, Aileen, Mauser, Peter J, Sellers, Shari, Terebetski, Jenna, Wang, Zhenyu, Ehrick, Jason D
Published in Therapeutic delivery (01.05.2018)
Published in Therapeutic delivery (01.05.2018)
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Journal Article
The in vitro and in vivo investigation of inhaled migraine therapies using a novel aerosol delivery system consisting of an air pressurized capsule device (APCD) in combination with a pMDI spacer for endotracheal dosing into beagle dogs
Sellers, Shari, Horodnik, Walter, House, Aileen, Wylie, Jennifer, Mauser, Peter, Garber, Natalie, Pu, Yu (Elaine), Berry, Julianne, Donovan, Brent
Published in Drug development and industrial pharmacy (02.12.2015)
Published in Drug development and industrial pharmacy (02.12.2015)
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Journal Article
Pharmacological characterization of the late phase reduction in lung functions and correlations with microvascular leakage and lung edema in allergen-challenged Brown Norway rats
Mauser, Peter J, House, Aileen, Jones, Howard, Correll, Craig, Boyce, Christopher, Chapman, Richard W
Published in Pulmonary pharmacology & therapeutics (01.12.2013)
Published in Pulmonary pharmacology & therapeutics (01.12.2013)
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Journal Article
Use of the Allay™ restraint collar to facilitate the measurement of ventilation in conscious rats
House, Aileen, Shafer, Richard, Shemesh, Yuval, Lomask, Joseph, Chapman, Richard W., Mauser, Peter J.
Published in Journal of pharmacological and toxicological methods (01.11.2014)
Published in Journal of pharmacological and toxicological methods (01.11.2014)
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Journal Article
Discovery of oral and inhaled PDE4 inhibitors
Ting, Pauline C., Lee, Joe F., Kuang, Rongze, Cao, Jianhua, Gu, Danlin, Huang, Ying, Liu, Zhidan, Aslanian, Robert G., Feng, Kung-I., Prelusky, Daniel, Lamca, James, House, Aileen, Phillips, Jonathan E., Wang, Peng, Wu, Ping, Lundell, Daniel, Chapman, Richard W., Celly, Chander S.
Published in Bioorganic & medicinal chemistry letters (15.10.2013)
Published in Bioorganic & medicinal chemistry letters (15.10.2013)
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Journal Article
Steroidal C-21 mercapto derivatives as dissociated steroids: Discovery of an inhaled dissociated steroid
Biju, Purakkattle, McCormick, Kevin, Aslanian, Robert, Berlin, Michael, Solomon, Daniel, Chapman, Richard, McLeod, Robbie, Prelusky, Daniel, Eckel, Stephen, Kelly, George, Natiello, Michelle, House, Aileen, Fernandez, Xiomara, Bitar, Rema, Phillips, Jonathan, Anthes, John
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
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Journal Article
Pharmacology of a potent and selective inhibitor of PDE4 for inhaled administration
Chapman, Richard W., House, Aileen, Richard, Jennifer, Prelusky, Dan, Lamca, James, Wang, Peng, Lundell, Dan, Wu, Ping, Ting, Pauline C., Lee, Joe F., Aslanian, Robert, Phillips, Jonathan E.
Published in European journal of pharmacology (25.09.2010)
Published in European journal of pharmacology (25.09.2010)
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Journal Article
Effect of inhaled roflumilast on the prevention and resolution of allergen-induced late phase airflow obstruction in Brown Norway rats
Chapman, Richard W., House, Aileen, Jones, Howard, Richard, Jennifer, Celly, Chander, Prelusky, Dan, Ting, Pauline, Hunter, John C., Lamca, James, Phillips, Jonathan E.
Published in European journal of pharmacology (01.10.2007)
Published in European journal of pharmacology (01.10.2007)
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Journal Article
Steroidal C-21 heteroaryl thioethers. Part 3: Pregn-4-eno-[3,2-c]pyrazole fused A ring modified steroids as selective glucocorticoid receptor modulators (dissociated steroids)
Biju, Purakkattle, Wang, Hongwu, Anthes, John, McCormick, Kevin, Aslanian, Robert, Berlin, Michael, Bitar, Rema, Lim, Yeon-Hee, Lee, Yoon Joo, Prelusky, Daniel, Mcleod, Robbie, Jia, Yanlin, Fernandez, Xiomora, Lieber, Gissela, Jimenez, Johanna, Eckel, Steve, House, Aileen, Chapman, Richard, Phillips, Jonathan
Published in Bioorganic & medicinal chemistry letters (01.05.2012)
Published in Bioorganic & medicinal chemistry letters (01.05.2012)
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Journal Article
Effect of mometasone furoate (MF)/formoterol fumarate (F) combination (MF/F) on late-phase responses in allergen-challenged Brown Norway rats
Chapman, Richard W, Curran, Aidan K, House, Aileen, Richard, Jennifer, Salisbury, Brian, Hunter, John C, Anthes, John C, Phillips, Jonathan E
Published in Pulmonary pharmacology & therapeutics (01.02.2011)
Published in Pulmonary pharmacology & therapeutics (01.02.2011)
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Journal Article
Steroidal C-21 heteroaryl thioethers (Part 2): Discovery of orally bioavailable selective glucocorticoid receptor modulators (dissociated steroids)
Biju, Purakkattle, McCormick, Kevin, Aslanian, Robert, Berlin, Michael, Solomon, Daniel, Wang, Hongwu, Lee, Yoon Joo, Bitar, Rema, Prelusky, Daniel, Mcleod, Robbie, Jia, Yanlin, Fernandez, Xiomora, Eckel, Stephen, House, Aileen, Lieber, Gissela, Jimenez, Johanna, Kelly, George, Chapman, Richard, Phillips, Jonathan, Anthes, John
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
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Journal Article
Temporal profile of forced expiratory lung function in allergen-challenged Brown–Norway rats
Celly, Chander S., House, Aileen, Sehring, Susan J., Zhang, Xiang Y., Jones, Howard, Hey, John A., Egan, Robert W., Chapman, Richard W.
Published in European journal of pharmacology (01.07.2006)
Published in European journal of pharmacology (01.07.2006)
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Journal Article
Antitussive activity of the tachykinin NK1 receptor antagonist, CP-99994, in dogs
CHAPMAN, Richard W, HOUSE, Aileen, FEI LIU, CELLY, Chander, HONG MEI, HEY, John A
Published in European journal of pharmacology (06.02.2004)
Published in European journal of pharmacology (06.02.2004)
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Journal Article
Cough reflex in allergic dogs
HOUSE, Aileen, CELLY, Chander, SKEANS, Susan, LAMCA, James, EGAN, Robert W, HEY, John A, CHAPMAN, Richard W
Published in European journal of pharmacology (25.05.2004)
Published in European journal of pharmacology (25.05.2004)
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Journal Article
Airway Closure after Antigen Challenge in Cynomolgus Monkeys: Effect of the Histamine H1 Receptor Antagonist, Chlorpheniramine Maleate
Skeans, Susan, Lamca, James E., House, Aileen, Celly, Chander S., Hey, John A., Chapman, Richard W.
Published in International archives of allergy and immunology (01.05.2005)
Published in International archives of allergy and immunology (01.05.2005)
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Journal Article
A simple noninvasive method to measure the cough reflex in dogs
Chapman, Richard W, House, Aileen, Skeans, Susan, Lamca, James, Egan, Robert W, Celly, Chander, Hey, John A
Published in Journal of pharmacological and toxicological methods (01.07.2001)
Published in Journal of pharmacological and toxicological methods (01.07.2001)
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