Blocking Hedgehog Survival Signaling at the Level of the GLI Genes Induces DNA Damage and Extensive Cell Death in Human Colon Carcinoma Cells
MAZUMDAR, Tapati, DEVECCHIO, Jennifer, AGYEMAN, Akwasi, TING SHI, HOUGHTON, Janet A
Published in Cancer research (Chicago, Ill.) (01.09.2011)
Published in Cancer research (Chicago, Ill.) (01.09.2011)
Get full text
Journal Article
Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding
Agyeman, Akwasi, Jha, Babal K, Mazumdar, Tapati, Houghton, Janet A
Published in Oncotarget (30.06.2014)
Published in Oncotarget (30.06.2014)
Get full text
Journal Article
Hedgehog Signaling Drives Cellular Survival in Human Colon Carcinoma Cells
MAZUMDAR, Tapati, DEVECCHIO, Jennifer, TING SHI, JONES, Janay, AGYEMAN, Akwasi, HOUGHTON, Janet A
Published in Cancer research (Chicago, Ill.) (01.02.2011)
Published in Cancer research (Chicago, Ill.) (01.02.2011)
Get full text
Journal Article
Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl–mediated drug resistance
Carew, Jennifer S., Nawrocki, Steffan T., Kahue, Charissa N., Zhang, Hui, Yang, Chunying, Chung, Linda, Houghton, Janet A., Huang, Peng, Giles, Francis J., Cleveland, John L.
Published in Blood (01.07.2007)
Published in Blood (01.07.2007)
Get full text
Journal Article
Hedgehog signaling regulates telomerase reverse transcriptase in human cancer cells
Mazumdar, Tapati, Sandhu, Ranjodh, Qadan, Maha, DeVecchio, Jennifer, Magloire, Victoria, Agyeman, Akwasi, Li, Bibo, Houghton, Janet A
Published in PloS one (25.09.2013)
Published in PloS one (25.09.2013)
Get full text
Journal Article
Inhibition of NF-κB Signaling by Quinacrine Is Cytotoxic to Human Colon Carcinoma Cell Lines and Is Synergistic in Combination with Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) or Oxaliplatin
Jani, Tanvi S., DeVecchio, Jennifer, Mazumdar, Tapati, Agyeman, Akwasi, Houghton, Janet A.
Published in The Journal of biological chemistry (18.06.2010)
Published in The Journal of biological chemistry (18.06.2010)
Get full text
Journal Article
The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer
Mazumdar, Tapati, DeVecchio, Jennifer, Agyeman, Akwasi, Shi, Ting, Houghton, Janet A
Published in Oncotarget (01.08.2011)
Published in Oncotarget (01.08.2011)
Get full text
Journal Article
An antiapoptotic BCL-2 family expression index predicts the response of chronic lymphocytic leukemia to ABT-737
Al-harbi, Sayer, Hill, Brian T., Mazumder, Suparna, Singh, Kamini, DeVecchio, Jennifer, Choudhary, Gaurav, Rybicki, Lisa A., Kalaycio, Matt, Maciejewski, Jaroslaw P., Houghton, Janet A., Almasan, Alexandru
Published in Blood (29.09.2011)
Published in Blood (29.09.2011)
Get full text
Journal Article
Targeting GLI by GANT61 involves mechanisms dependent on inhibition of both transcription and DNA licensing
Zhang, Ruowen, Wu, Jiahui, Ferrandon, Sylvain, Glowacki, Katie J, Houghton, Janet A
Published in Oncotarget (06.12.2016)
Published in Oncotarget (06.12.2016)
Get full text
Journal Article
Myc regulates aggresome formation, the induction of Noxa, and apoptosis in response to the combination of bortezomib and SAHA
Nawrocki, Steffan T., Carew, Jennifer S., Maclean, Kirsteen H., Courage, James F., Huang, Peng, Houghton, Janet A., Cleveland, John L., Giles, Francis J., McConkey, David J.
Published in Blood (01.10.2008)
Published in Blood (01.10.2008)
Get full text
Journal Article
Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae
MARTIN, Sophie, PHILLIPS, Darren C, SZEKELY-SZUCS, Kinga, ELGHAZI, Lynda, DESMOTS, Fabienne, HOUGHTON, Janet A
Published in Cancer research (Chicago, Ill.) (15.12.2005)
Published in Cancer research (Chicago, Ill.) (15.12.2005)
Get full text
Journal Article
Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines
IZERADJENE, Kamel, DOUGLAS, Leslie, TILLMAN, David M, DELANEY, Addison B, HOUGHTON, Janet A
Published in Cancer research (Chicago, Ill.) (15.08.2005)
Published in Cancer research (Chicago, Ill.) (15.08.2005)
Get full text
Journal Article
ATP modulates PTEN subcellular localization in multiple cancer cell lines
Lobo, Glenn P., Waite, Kristin A., Planchon, Sarah M., Romigh, Todd, Houghton, Janet A., Eng, Charis
Published in Human molecular genetics (15.09.2008)
Published in Human molecular genetics (15.09.2008)
Get full text
Journal Article
Sphingosine-induced apoptosis in rhabdomyosarcoma cell lines is dependent on pre-mitochondrial Bax activation and post-mitochondrial caspases
Phillips, Darren C, Martin, Sophie, Doyle, Belinda T, Houghton, Janet A
Published in Cancer research (Chicago, Ill.) (15.01.2007)
Published in Cancer research (Chicago, Ill.) (15.01.2007)
Get full text
Journal Article
Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria independent of protein kinase C
TILLMAN, David M, IZERADJENE, Kamel, SZUCS, Kinga Szekely, DOUGLAS, Leslie, HOUGHTON, Janet A
Published in Cancer research (Chicago, Ill.) (15.08.2003)
Get full text
Published in Cancer research (Chicago, Ill.) (15.08.2003)
Journal Article