Structure and dynamics of a mycobacterial type VII secretion system
Bunduc, Catalin M., Fahrenkamp, Dirk, Wald, Jiri, Ummels, Roy, Bitter, Wilbert, Houben, Edith N. G., Marlovits, Thomas C.
Published in Nature (London) (20.05.2021)
Published in Nature (London) (20.05.2021)
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Essential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria
Ates, Louis S, Ummels, Roy, Commandeur, Susanna, van de Weerd, Robert, van der Weerd, Robert, Sparrius, Marion, Weerdenburg, Eveline, Alber, Marina, Kalscheuer, Rainer, Piersma, Sander R, Abdallah, Abdallah M, Abd El Ghany, Moataz, Abdel-Haleem, Alyaa M, Pain, Arnab, Jiménez, Connie R, Bitter, Wilbert, Houben, Edith N G
Published in PLoS genetics (01.05.2015)
Published in PLoS genetics (01.05.2015)
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Take five — Type VII secretion systems of Mycobacteria
Houben, Edith N.G., Korotkov, Konstantin V., Bitter, Wilbert
Published in Biochimica et biophysica acta (01.08.2014)
Published in Biochimica et biophysica acta (01.08.2014)
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Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins
Sani, Musa, Houben, Edith N G, Geurtsen, Jeroen, Pierson, Jason, de Punder, Karin, van Zon, Maaike, Wever, Brigitte, Piersma, Sander R, Jiménez, Connie R, Daffé, Mamadou, Appelmelk, Ben J, Bitter, Wilbert, van der Wel, Nicole, Peters, Peter J
Published in PLoS pathogens (01.03.2010)
Published in PLoS pathogens (01.03.2010)
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EspH is a hypervirulence factor for Mycobacterium marinum and essential for the secretion of the ESX-1 substrates EspE and EspF
Phan, Trang H, van Leeuwen, Lisanne M, Kuijl, Coen, Ummels, Roy, van Stempvoort, Gunny, Rubio-Canalejas, Alba, Piersma, Sander R, Jiménez, Connie R, van der Sar, Astrid M, Houben, Edith N G, Bitter, Wilbert
Published in PLoS pathogens (01.08.2018)
Published in PLoS pathogens (01.08.2018)
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Composition of the type VII secretion system membrane complex
Houben, Edith N. G., Bestebroer, Jovanka, Ummels, Roy, Wilson, Louis, Piersma, Sander R., Jiménez, Connie R., Ottenhoff, Tom H. M., Luirink, Joen, Bitter, Wilbert
Published in Molecular microbiology (01.10.2012)
Published in Molecular microbiology (01.10.2012)
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Systematic genetic nomenclature for type VII secretion systems
Bitter, Wilbert, Houben, Edith N G, Bottai, Daria, Brodin, Priscille, Brown, Eric J, Cox, Jeffery S, Derbyshire, Keith, Fortune, Sarah M, Gao, Lian-Yong, Liu, Jun, Gey van Pittius, Nicolaas C, Pym, Alexander S, Rubin, Eric J, Sherman, David R, Cole, Stewart T, Brosch, Roland
Published in PLoS pathogens (01.10.2009)
Published in PLoS pathogens (01.10.2009)
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Species‐specific secretion of ESX‐5 type VII substrates is determined by the linker 2 of EccC5
Bunduc, Catalin M., Ummels, Roy, Bitter, Wilbert, Houben, Edith N. G.
Published in Molecular microbiology (01.07.2020)
Published in Molecular microbiology (01.07.2020)
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Modification of a PE/PPE substrate pair reroutes an Esx substrate pair from the mycobacterial ESX-1 type VII secretion system to the ESX-5 system
Damen, Merel P.M., Phan, Trang H., Ummels, Roy, Rubio-Canalejas, Alba, Bitter, Wilbert, Houben, Edith N.G.
Published in The Journal of biological chemistry (01.05.2020)
Published in The Journal of biological chemistry (01.05.2020)
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Dendritic Cell Stimulation by Mycobacterial Hsp70 Is Mediated Through CCR5
Floto, R. Andres, MacAry, Paul A, Boname, Jessica M, Mien, Tan Suet, Kampmann, Beate, Hair, James R, Huey, Oh Seen, Houben, Edith N.G, Pieters, Jean, Day, Cheryl, Oehlmann, Wulf, Singh, Mahavir, Smith, Kenneth G.C, Lehner, Paul J
Published in Science (American Association for the Advancement of Science) (20.10.2006)
Published in Science (American Association for the Advancement of Science) (20.10.2006)
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Mutations in ppe38 block PE_PGRS secretion and increase virulence of Mycobacterium tuberculosis
Ates, Louis S., Dippenaar, Anzaan, Ummels, Roy, Piersma, Sander R., van der Woude, Aniek D., van der Kuij, Kim, Le Chevalier, Fabien, Mata-Espinosa, Dulce, Barrios-Payán, Jorge, Marquina-Castillo, Brenda, Guapillo, Carolina, Jiménez, Connie R., Pain, Arnab, Houben, Edith N. G., Warren, Robin M., Brosch, Roland, Hernández-Pando, Rogelio, Bitter, Wilbert
Published in Nature microbiology (01.02.2018)
Published in Nature microbiology (01.02.2018)
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Structure of the Mycobacterium tuberculosis type VII secretion system chaperone EspG5 in complex with PE25–PPE41 dimer
Korotkova, Natalia, Freire, Diana, Phan, Trang H., Ummels, Roy, Creekmore, Christopher C., Evans, Timothy J., Wilmanns, Matthias, Bitter, Wilbert, Parret, Annabel H. A., Houben, Edith N. G., Korotkov, Konstantin V.
Published in Molecular microbiology (01.10.2014)
Published in Molecular microbiology (01.10.2014)
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Protease domain and transmembrane domain of the type VII secretion mycosin protease determine system-specific functioning in mycobacteria
van Winden, Vincent J.C., Damen, Merel P.M., Ummels, Roy, Bitter, Wilbert, Houben, Edith N.G.
Published in The Journal of biological chemistry (29.03.2019)
Published in The Journal of biological chemistry (29.03.2019)
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Journal Article
A Chimeric EccB-MycP Fusion Protein is Functional and a Stable Component of the ESX-5 Type VII Secretion System Membrane Complex
van Winden, Vincent J.C., Bunduc, Catalin M., Ummels, Roy, Bitter, Wilbert, Houben, Edith N.G.
Published in Journal of molecular biology (14.02.2020)
Published in Journal of molecular biology (14.02.2020)
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The ESX-1 Substrate PPE68 Has a Key Function in ESX-1-Mediated Secretion in Mycobacterium marinum
Damen, Merel P M, Meijers, Aniek S, Keizer, Esther M, Piersma, Sander R, Jiménez, Connie R, Kuijl, Coenraad P, Bitter, Wilbert, Houben, Edith N G
Published in mBio (20.12.2022)
Published in mBio (20.12.2022)
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Journal Article
Mycosins Are Required for the Stabilization of the ESX-1 and ESX-5 Type VII Secretion Membrane Complexes
van Winden, Vincent J C, Ummels, Roy, Piersma, Sander R, Jiménez, Connie R, Korotkov, Konstantin V, Bitter, Wilbert, Houben, Edith N G
Published in mBio (18.10.2016)
Published in mBio (18.10.2016)
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Journal Article
Species-specific secretion of ESX-5 type VII substrates is determined by the linker 2 of EccC 5
Bunduc, Catalin M, Ummels, Roy, Bitter, Wilbert, Houben, Edith N G
Published in Molecular microbiology (01.07.2020)
Published in Molecular microbiology (01.07.2020)
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