Plasma membrane anchored nanosensor for quantifying endogenous production of H2O2 in living cells
Hosogi, Shigekuni, Marunaka, Yoshinori, Ashihara, Eishi, Yamada, Tadaaki, Sumino, Ayumi, Tanaka, Hideo, Puppulin, Leonardo
Published in Biosensors & bioelectronics (01.05.2021)
Published in Biosensors & bioelectronics (01.05.2021)
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Journal Article
The CDK4/6-UCHL5-BRD4 axis confers resistance to BET inhibitors in MLL-rearranged leukemia cells by suppressing BRD4 protein degradation
Amari, Keigo, Sasagawa, Satoru, Imayoshi, Natsuki, Toda, Yuki, Hosogi, Shigekuni, Imamura, Toshihiko, Ashihara, Eishi
Published in Biochemical and biophysical research communications (15.01.2022)
Published in Biochemical and biophysical research communications (15.01.2022)
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Journal Article
Bioconjugation strategy for cell surface labelling with gold nanostructures designed for highly localized pH measurement
Puppulin, Leonardo, Hosogi, Shigekuni, Sun, Hongxin, Matsuo, Kazuhiko, Inui, Toshio, Kumamoto, Yasuaki, Suzaki, Toshinobu, Tanaka, Hideo, Marunaka, Yoshinori
Published in Nature communications (11.12.2018)
Published in Nature communications (11.12.2018)
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Journal Article
Mumefural prevents insulin resistance and amyloid-beta accumulation in the brain by improving lowered interstitial fluid pH in type 2 diabetes mellitus
Hosogi, Shigekuni, KUWAHARA, Atsukazu, KUWAHARA, Yuko, TANAKA, Saori, SHIMAMOTO, Chikao, TAGAWA, Noriko, KATO, Ikuo, YOSHIMOTO, Kanji, AOI, Wataru, TAKATA, Kazuyuki, MIYAZAKI, Hiroaki, NIISATO, Naomi, TSUBO, Yasuhiro, YAGI, Katsumi, NAKAHARI, Takashi, MARUNAKA, Yoshinori
Published in Biomedical Research (25.01.2023)
Published in Biomedical Research (25.01.2023)
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Journal Article
Ambroxol-Enhanced Frequency and Amplitude of Beating Cilia Controlled by a Voltage-Gated Ca2+ Channel, Cav1.2, via pHi Increase and [Cl−]i Decrease in the Lung Airway Epithelial Cells of Mice
Nakahari, Takashi, Suzuki, Chihiro, Kawaguchi, Kotoku, Hosogi, Shigekuni, Tanaka, Saori, Asano, Shinji, Inui, Toshio, Marunaka, Yoshinori
Published in International journal of molecular sciences (01.12.2023)
Published in International journal of molecular sciences (01.12.2023)
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Journal Article
Impairment of lysosomal activity as a therapeutic modality targeting cancer stem cells of embryonal rhabdomyosarcoma cell line RD
Salerno, Manuela, Avnet, Sofia, Bonuccelli, Gloria, Hosogi, Shigekuni, Granchi, Donatella, Baldini, Nicola
Published in PloS one (20.10.2014)
Published in PloS one (20.10.2014)
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Journal Article
CN470 is a BET/CBP/p300 multi-bromodomain inhibitor and has an anti-tumor activity against MLL-rearranged acute lymphoblastic leukemia
Imayoshi, Natsuki, Yoshioka, Makoto, Tanaka, Kuniaki, Yang, Shyh-Ming, Akahane, Koshi, Toda, Yuki, Hosogi, Shigekuni, Inukai, Takeshi, Okada, Seiji, Maloney, David J., Nakahata, Tatsutoshi, Takita, Junko, Kato, Itaru, Ashihara, Eishi
Published in Biochemical and biophysical research communications (29.01.2022)
Published in Biochemical and biophysical research communications (29.01.2022)
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Journal Article
Cytosolic chloride ion is a key factor in lysosomal acidification and function of autophagy in human gastric cancer cell
Hosogi, Shigekuni, Kusuzaki, Katsuyuki, Inui, Toshio, Wang, Xiangdong, Marunaka, Yoshinori
Published in Journal of cellular and molecular medicine (01.06.2014)
Published in Journal of cellular and molecular medicine (01.06.2014)
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Journal Article
Ambroxol-enhanced ciliary beating via voltage-gated Ca2+ channels in mouse airway ciliated cells
Saito, Daichi, Suzuki, Chihiro, Tanaka, Saori, Hosogi, Shigekuni, Kawaguchi, Kotoku, Asano, Shinji, Okamoto, Shohta, Yasuda, Makoto, Hirano, Shigeru, Inui, Toshio, Marunaka, Yoshinori, Nakahari, Takashi
Published in European journal of pharmacology (15.02.2023)
Published in European journal of pharmacology (15.02.2023)
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Journal Article
6-Hydroxythiobinupharidine Inhibits Migration of LM8 Osteosarcoma Cells by Decreasing Expression of LIM Domain Kinase 1
Yoshizawa, Masato, Nakamura, Seikou, Sugiyama, Yuki, Tamai, Shiori, Ishida, Yukiko, Sueyoshi, Mari, Toda, Yuki, Hosogi, Shigekuni, Yano, Yoshitaka, Ashihara, Eishi
Published in Anticancer research (01.12.2019)
Published in Anticancer research (01.12.2019)
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Journal Article
DJ-1 Contributes to Self-renewal of Stem Cells in the U87-MG Glioblastoma Cell Line
Toda, Yuki, Yoshimura, Ryosuke, Itahara, Masao, Imai, Yuri, Yamada, Kanae, Uno, Tomoko, Nakata, Susumu, Hosogi, Shigekuni, Takata, Kazuyuki, Ashihara, Eishi
Published in Anticancer research (01.11.2019)
Published in Anticancer research (01.11.2019)
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Journal Article
[Ca2+]i modulation of cAMP‐stimulated ciliary beat frequency via PDE1 in airway ciliary cells of mice
Kogiso, Haruka, Hosogi, Shigekuni, Ikeuchi, Yukiko, Tanaka, Saori, Inui, Toshio, Marunaka, Yoshinori, Nakahari, Takashi
Published in Experimental physiology (01.03.2018)
Published in Experimental physiology (01.03.2018)
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Journal Article
TRPV3-ANO1 interaction positively regulates wound healing in keratinocytes
Yamanoi, Yu, Lei, Jing, Takayama, Yasunori, Hosogi, Shigekuni, Marunaka, Yoshinori, Tominaga, Makoto
Published in Communications biology (23.01.2023)
Published in Communications biology (23.01.2023)
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Journal Article
A low [Ca2+]i-induced enhancement of cAMP-activated ciliary beating by PDE1A inhibition in mouse airway cilia
Kogiso, Haruka, Hosogi, Shigekuni, Ikeuchi, Yukiko, Tanaka, Saori, Shimamoto, Chikao, Matsumura, Hitoshi, Nakano, Takashi, Sano, Koh-ichi, Inui, Toshio, Marunaka, Yoshinori, Nakahari, Takashi
Published in Pflügers Archiv (01.09.2017)
Published in Pflügers Archiv (01.09.2017)
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Journal Article
Measurement of [Cl - ] i unaffected by the cell volume change using MQAE-based two-photon microscopy in airway ciliary cells of mice
Ikeuchi, Yukiko, Kogiso, Haruka, Hosogi, Shigekuni, Tanaka, Saori, Shimamoto, Chikao, Inui, Toshio, Nakahari, Takashi, Marunaka, Yoshinori
Published in The journal of physiological sciences (01.03.2018)
Published in The journal of physiological sciences (01.03.2018)
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Journal Article
Ciliary beating amplitude controlled by intracellular Cl− and a high rate of CO2 production in ciliated human nasal epithelial cells
Inui, Taka-aki, Murakami, Kentaro, Yasuda, Makoto, Hirano, Shigeru, Ikeuchi, Yukiko, Kogiso, Haruka, Hosogi, Shigekuni, Inui, Toshio, Marunaka, Yoshinori, Nakahari, Takashi
Published in Pflügers Archiv (01.08.2019)
Published in Pflügers Archiv (01.08.2019)
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Journal Article
Targeting acidic pre-metastatic niche in lungs by pH low insertion peptide and its utility for anti-metastatic therapy
Matsui, Toma, Toda, Yuki, Sato, Haruka, Itagaki, Rina, Konishi, Kazuya, Moshnikova, Anna, Andreev, Oleg A, Hosogi, Shigekuni, Reshetnyak, Yana K, Ashihara, Eishi
Published in Frontiers in oncology (15.11.2023)
Published in Frontiers in oncology (15.11.2023)
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Journal Article
Knockdown of ezrin causes intrahepatic cholestasis by the dysregulation of bile fluidity in the bile duct epithelium in mice
Hatano, Ryo, Akiyama, Kaori, Tamura, Atsushi, Hosogi, Shigekuni, Marunaka, Yoshinori, Caplan, Michael J., Ueno, Yoshiyuki, Tsukita, Sachiko, Asano, Shinji
Published in Hepatology (Baltimore, Md.) (01.05.2015)
Published in Hepatology (Baltimore, Md.) (01.05.2015)
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Journal Article
Carbocisteine stimulated an increase in ciliary bend angle via a decrease in [Cl−]i in mouse airway cilia
Ikeuchi, Yukiko, Kogiso, Haruka, Hosogi, Shigekuni, Tanaka, Saori, Shimamoto, Chikao, Matsumura, Hitoshi, Inui, Toshio, Marunaka, Yoshinori, Nakahari, Takashi
Published in Pflügers Archiv (01.02.2019)
Published in Pflügers Archiv (01.02.2019)
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