The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis
Sato, Michio, Kadomatsu, Tsuyoshi, Miyata, Keishi, Warren, Junco S, Tian, Zhe, Zhu, Shunshun, Horiguchi, Haruki, Makaju, Aman, Bakhtina, Anna, Morinaga, Jun, Sugizaki, Taichi, Hirashima, Kaname, Yoshinobu, Kumiko, Imasaka, Mai, Araki, Masatake, Komohara, Yoshihiro, Wakayama, Tomohiko, Nakagawa, Shinichi, Franklin, Sarah, Node, Koichi, Araki, Kimi, Oike, Yuichi
Published in Nature communications (05.05.2021)
Published in Nature communications (05.05.2021)
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Aging- and obesity-related peri-muscular adipose tissue accelerates muscle atrophy
Zhu, Shunshun, Tian, Zhe, Torigoe, Daisuke, Zhao, Jiabin, Xie, Peiyu, Sugizaki, Taichi, Sato, Michio, Horiguchi, Haruki, Terada, Kazutoyo, Kadomatsu, Tsuyoshi, Miyata, Keishi, Oike, Yuichi
Published in PloS one (23.08.2019)
Published in PloS one (23.08.2019)
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Tumor cell‐derived angiopoietin‐like protein 2 establishes a preference for glycolytic metabolism in lung cancer cells
Osumi, Hironobu, Horiguchi, Haruki, Kadomatsu, Tsuyoshi, Tashiro, Kyosei, Morinaga, Jun, Takahashi, Takashi, Ikeda, Koei, Ito, Takaaki, Suzuki, Makoto, Endo, Motoyoshi, Oike, Yuichi
Published in Cancer science (01.04.2020)
Published in Cancer science (01.04.2020)
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ANGPTL2 expression in the intestinal stem cell niche controls epithelial regeneration and homeostasis
Horiguchi, Haruki, Endo, Motoyoshi, Kawane, Kohki, Kadomatsu, Tsuyoshi, Terada, Kazutoyo, Morinaga, Jun, Araki, Kimi, Miyata, Keishi, Oike, Yuichi
Published in The EMBO journal (15.02.2017)
Published in The EMBO journal (15.02.2017)
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Association of circulating ANGPTL 3, 4, and 8 levels with medical status in a population undergoing routine medical checkups: A cross-sectional study
Morinaga, Jun, Zhao, Jiabin, Endo, Motoyoshi, Kadomatsu, Tsuyoshi, Miyata, Keishi, Sugizaki, Taichi, Okadome, Yusuke, Tian, Zhe, Horiguchi, Haruki, Miyashita, Kazuya, Maruyama, Nobuhiro, Mukoyama, Masashi, Oike, Yuichi
Published in PloS one (14.03.2018)
Published in PloS one (14.03.2018)
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Loss of Endogenous HMGB2 Promotes Cardiac Dysfunction and Pressure Overload-Induced Heart Failure in Mice
Sato, Michio, Miyata, Keishi, Tian, Zhe, Kadomatsu, Tsuyoshi, Ujihara, Yoshihiro, Morinaga, Jun, Horiguchi, Haruki, Endo, Motoyoshi, Zhao, Jiabin, Zhu, Shunshun, Sugizaki, Taichi, Igata, Kimihiro, Muramatsu, Masashi, Minami, Takashi, Ito, Takashi, Bianchi, Marco E, Mohri, Satoshi, Araki, Kimi, Node, Koichi, Oike, Yuichi
Published in Circulation Journal (25.01.2019)
Published in Circulation Journal (25.01.2019)
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Role of Endothelial Cell–Derived Angptl2 in Vascular Inflammation Leading to Endothelial Dysfunction and Atherosclerosis Progression
Horio, Eiji, Kadomatsu, Tsuyoshi, Miyata, Keishi, Arai, Yasumichi, Hosokawa, Kentaro, Doi, Yasufumi, Ninomiya, Toshiharu, Horiguchi, Haruki, Endo, Motoyoshi, Tabata, Mitsuhisa, Tazume, Hirokazu, Tian, Zhe, Takahashi, Otowa, Terada, Kazutoyo, Takeya, Motohiro, Hao, Hiroyuki, Hirose, Nobuyoshi, Minami, Takashi, Suda, Toshio, Kiyohara, Yutaka, Ogawa, Hisao, Kaikita, Koichi, Oike, Yuichi
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2014)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2014)
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Circulating ANGPTL2 Levels Increase in Humans and Mice Exhibiting Cardiac Dysfunction
Tian, Zhe, Miyata, Keishi, Morinaga, Jun, Horiguchi, Haruki, Kadomatsu, Tsuyoshi, Endo, Motoyoshi, Zhao, Jiabin, Zhu, Shunshun, Sugizaki, Taichi, Sato, Michio, Terada, Kazutoyo, Okumura, Takahiro, Murohara, Toyoaki, Oike, Yuichi
Published in Circulation Journal (2018)
Published in Circulation Journal (2018)
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Cdk5rap1-Mediated 2-Methylthio Modification of Mitochondrial tRNAs Governs Protein Translation and Contributes to Myopathy in Mice and Humans
Wei, Fan-Yan, Zhou, Bo, Suzuki, Takeo, Miyata, Keishi, Ujihara, Yoshihiro, Horiguchi, Haruki, Takahashi, Nozomu, Xie, Peiyu, Michiue, Hiroyuki, Fujimura, Atsushi, Kaitsuka, Taku, Matsui, Hideki, Koga, Yasutoshi, Mohri, Satoshi, Suzuki, Tsutomu, Oike, Yuichi, Tomizawa, Kazuhito
Published in Cell metabolism (03.03.2015)
Published in Cell metabolism (03.03.2015)
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Angiopoietin-like Protein 2 Is an Important Facilitator of Inflammatory Carcinogenesis and Metastasis
AOI, Jun, ENDO, Motoyoshi, JINNIN, Masatoshi, ITO, Takaaki, HIRAKAWA, Satoshi, IHN, Hironobu, OIKE, Yuichi, KADOMATSU, Tsuyoshi, MIYATA, Keishi, NAKANO, Masahiro, HORIGUCHI, Haruki, OGATA, Aki, ODAGIRI, Haruki, YANO, Masato, ARAKI, Kimi
Published in Cancer research (Chicago, Ill.) (15.12.2011)
Published in Cancer research (Chicago, Ill.) (15.12.2011)
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Dual functions of angiopoietin-like protein 2 signaling in tumor progression and anti-tumor immunity
Horiguchi, Haruki, Kadomatsu, Tsuyoshi, Kurahashi, Ryoma, Hara, Chiaki, Miyata, Keishi, Baba, Masaya, Osumi, Hironobu, Terada, Kazutoyo, Araki, Kimi, Takai, Toshiyuki, Kamba, Tomomi, Linehan, W Marston, Moroishi, Toshiro, Oike, Yuichi
Published in Genes & development (01.12.2019)
Published in Genes & development (01.12.2019)
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ANGPTL2‐mediated epigenetic repression of MHC‐I in tumor cells accelerates tumor immune evasion
Kadomatsu, Tsuyoshi, Hara, Chiaki, Kurahashi, Ryoma, Horiguchi, Haruki, Morinaga, Jun, Miyata, Keishi, Kurano, Sohtaro, Kanemaru, Hisashi, Fukushima, Satoshi, Araki, Kimi, Baba, Masaya, Linehan, W. Marston, Kamba, Tomomi, Oike, Yuichi
Published in Molecular oncology (01.12.2023)
Published in Molecular oncology (01.12.2023)
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Tumor Cell―Derived Angiopoietin-like Protein ANGPTL2 Is a Critical Driver of Metastasis
ENDO, Motoyoshi, NAKANO, Masahiro, ODAGIRI, Haruki, MASUDA, Tetsuro, HARADA, Masahiko, HORIO, Hirotoshi, HISHIMA, Tsunekazu, NOMORI, Hiroaki, ITO, Takaaki, YAMAMOTO, Yutaka, MINAMI, Takashi, OKADA, Seiji, KADOMATSU, Tsuyoshi, TAKAHASHI, Takashi, MOCHIZUKI, Naoki, IWASE, Hirotaka, OIKE, Yuichi, FUKUHARA, Shigetomo, KURODA, Hiroaki, MIKAMI, Shuji, TAI HATO, JUN AOI, HORIGUCHI, Haruki, MIYATA, Keishi
Published in Cancer research (Chicago, Ill.) (01.04.2012)
Published in Cancer research (Chicago, Ill.) (01.04.2012)
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ANGPTL2 activity in cardiac pathologies accelerates heart failure by perturbing cardiac function and energy metabolism
Tian, Zhe, Miyata, Keishi, Kadomatsu, Tsuyoshi, Horiguchi, Haruki, Fukushima, Hiroyuki, Tohyama, Shugo, Ujihara, Yoshihiro, Okumura, Takahiro, Yamaguchi, Satoshi, Zhao, Jiabin, Endo, Motoyoshi, Morinaga, Jun, Sato, Michio, Sugizaki, Taichi, Zhu, Shunshun, Terada, Kazutoyo, Sakaguchi, Hisashi, Komohara, Yoshihiro, Takeya, Motohiro, Takeda, Naoki, Araki, Kimi, Manabe, Ichiro, Fukuda, Keiichi, Otsu, Kinya, Wada, Jun, Murohara, Toyoaki, Mohri, Satoshi, Yamashita, Jun K, Sano, Motoaki, Oike, Yuichi
Published in Nature communications (28.09.2016)
Published in Nature communications (28.09.2016)
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Increased numbers of pre-operative circulating monocytes predict risk of developing cardiac surgery-associated acute kidney injury in conditions requiring cardio pulmonary bypass
Okadome, Yusuke, Morinaga, Jun, Yamanouchi, Yoshinori, Matsunaga, Eiji, Fukami, Hirotaka, Kadomatsu, Tsuyoshi, Horiguchi, Haruki, Sato, Michio, Sugizaki, Taichi, Hayata, Manabu, Sakaguchi, Takeshi, Hirayama, Ryo, Ishimura, Tatsuhiro, Kuwabara, Takashige, Usuku, Koichiro, Yamamoto, Tatsuo, Mukoyama, Masashi, Suzuki, Ryusuke, Fukui, Toshihiro, Oike, Yuichi
Published in Clinical and experimental nephrology (01.04.2023)
Published in Clinical and experimental nephrology (01.04.2023)
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Circulating angiopoietin-like protein 2 levels and arterial stiffness in patients receiving maintenance hemodialysis: A cross-sectional study
Fukami, Hirotaka, Morinaga, Jun, Okadome, Yusuke, Nishiguchi, Yoshihiko, Iwata, Yasunobu, Kanki, Tomoko, Nakagawa, Terumasa, Izumi, Yuichiro, Kakizoe, Yutaka, Kuwabara, Takashige, Horiguchi, Haruki, Sato, Michio, Kadomatsu, Tsuyoshi, Miyata, Keishi, Tajiri, Tetsuya, Oike, Yuichi, Mukoyama, Masashi
Published in Atherosclerosis (01.12.2020)
Published in Atherosclerosis (01.12.2020)
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Macrophage-Derived Angiopoietin-Like Protein 2 Accelerates Development of Abdominal Aortic Aneurysm
Tazume, Hirokazu, Miyata, Keishi, Tian, Zhe, Endo, Motoyoshi, Horiguchi, Haruki, Takahashi, Otowa, Horio, Eiji, Tsukano, Hiroto, Kadomatsu, Tsuyoshi, Nakashima, Yukiko, Kunitomo, Ryuji, Kaneko, Yasushi, Moriyama, Shuji, Sakaguchi, Hisashi, Okamoto, Ken, Hara, Masahiko, Yoshinaga, Takashi, Yoshimura, Koichi, Aoki, Hiroki, Araki, Kimi, Hao, Hiroyuki, Kawasuji, Michio, Oike, Yuichi
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.2012)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.2012)
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ANGPTL2 increases bone metastasis of breast cancer cells through enhancing CXCR4 signaling
Masuda, Tetsuro, Endo, Motoyoshi, Yamamoto, Yutaka, Odagiri, Haruki, Kadomatsu, Tsuyoshi, Nakamura, Takayuki, Tanoue, Hironori, Ito, Hitoshi, Yugami, Masaki, Miyata, Keishi, Morinaga, Jun, Horiguchi, Haruki, Motokawa, Ikuyo, Terada, Kazutoyo, Morioka, Masaki Suimye, Manabe, Ichiro, Iwase, Hirotaka, Mizuta, Hiroshi, Oike, Yuichi
Published in Scientific reports (16.03.2015)
Published in Scientific reports (16.03.2015)
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The secreted protein ANGPTL2 promotes metastasis of osteosarcoma cells through integrin α5β1, p38 MAPK, and matrix metalloproteinases
Odagiri, Haruki, Kadomatsu, Tsuyoshi, Endo, Motoyoshi, Masuda, Tetsuro, Morioka, Masaki Suimye, Fukuhara, Shigetomo, Miyamoto, Takeshi, Kobayashi, Eisuke, Miyata, Keishi, Aoi, Jun, Horiguchi, Haruki, Nishimura, Naotaka, Terada, Kazutoyo, Yakushiji, Toshitake, Manabe, Ichiro, Mochizuki, Naoki, Mizuta, Hiroshi, Oike, Yuichi
Published in Science signaling (21.01.2014)
Published in Science signaling (21.01.2014)
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Journal Article
Angiopoietin-like protein 2 accelerates carcinogenesis by activating chronic inflammation and oxidative stress
Aoi, Jun, Endo, Motoyoshi, Kadomatsu, Tsuyoshi, Miyata, Keishi, Ogata, Aki, Horiguchi, Haruki, Odagiri, Haruki, Masuda, Tetsuro, Fukushima, Satoshi, Jinnin, Masatoshi, Hirakawa, Satoshi, Sawa, Tomohiro, Akaike, Takaaki, Ihn, Hironobu, Oike, Yuichi
Published in Molecular cancer research (01.02.2014)
Published in Molecular cancer research (01.02.2014)
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