Evaluation of Parent- and Metabolite-Induced Mitochondrial Toxicities Using CYP-Introduced HepG2 cells
Takemura, Akinori, Gong, Simin, Sato, Tomoyuki, Kawaguchi, Moemi, Sekine, Shuichi, Kazuki, Yasuhiro, Horie, Toru, Ito, Kousei
Published in Journal of pharmaceutical sciences (01.09.2021)
Published in Journal of pharmaceutical sciences (01.09.2021)
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Non-invasive Measurement of Skin Autofluorescence as a Beneficial Surrogate Marker for Atherosclerosis in Patients with Type 2 Diabetes
Temma, Jin, Matsuhisa, Munehide, Horie, Toru, Kuroda, Akio, Mori, Hiroyasu, Tamaki, Motoyuki, Endo, Itsuro, Aihara, Ken-ichi, Abe, Masahiro, Matsumoto, Toshio
Published in The Journal of Medical Investigation (2015)
Published in The Journal of Medical Investigation (2015)
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Fluorometric assessment of acetaminophen-induced toxicity in rat hepatocyte spheroids seeded on micro-space cell culture plates
Sanoh, Seigo, Santoh, Masataka, Takagi, Masashi, Kanayama, Tatsuya, Sugihara, Kazumi, Kotake, Yaichiro, Ejiri, Yoko, Horie, Toru, Kitamura, Shigeyuki, Ohta, Shigeru
Published in Toxicology in vitro (01.09.2014)
Published in Toxicology in vitro (01.09.2014)
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CYP2C9-Catalyzed Metabolism of S-Warfarin to 7-Hydroxywarfarin in Vivo and in Vitro in Chimeric Mice with Humanized Liver
INOUE, Tae, NITTA, Kayoko, SUGIHARA, Kazumi, HORIE, Toru, KITAMURA, Shigeyuki, OHTA, Shigeru
Published in Drug metabolism and disposition (01.12.2008)
Published in Drug metabolism and disposition (01.12.2008)
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EXPRESSION OF HUMAN CYTOCHROMES P450 IN CHIMERIC MICE WITH HUMANIZED LIVER
KATOH, Miki, MATSUI, Tomohito, NAKAJIMA, Miki, TATENO, Chise, KATAOKA, Miho, SOENO, Yoshinori, HORIE, Toru, IWASAKI, Kazuhide, YOSHIZATO, Katsutoshi, YOKOI, Tsuyoshi
Published in Drug metabolism and disposition (01.12.2004)
Published in Drug metabolism and disposition (01.12.2004)
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Journal Article
Secretion of Albumin and Induction of CYP1A2 and CYP3A4 in Novel Three-dimensional Culture System for Human Hepatocytes using Micro-space Plate
Nishimura, Masuhiro, Hagi, Mieko, Ejiri, Yoko, Kishimoto, Sanae, Horie, Toru, Narimatsu, Shizuo, Naito, Shinsaku
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2010)
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2010)
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cDNA Cloning of the Hepatocyte Canalicular Isoform of the Multidrug Resistance Protein, cMrp, Reveals a Novel Conjugate Export Pump Deficient in Hyperbilirubinemic Mutant Rats
Büchler, M, König, J, Brom, M, Kartenbeck, J, Spring, H, Horie, T, Keppler, D
Published in The Journal of biological chemistry (21.06.1996)
Published in The Journal of biological chemistry (21.06.1996)
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Journal Article
Expression Levels of Drug-Metabolizing Enzyme, Transporter, and Nuclear Receptor mRNAs in a Novel Three-Dimensional Culture System for Human Hepatocytes Using Micro-space Plates
Nishimura, Masuhiro, Ejiri, Yoko, Kishimoto, Sanae, Suzuki, Satoshi, Satoh, Tetsuo, Horie, Toru, Narimatsu, Shizuo, Naito, Shinsaku
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2011)
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2011)
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Activation of Morphine Glucuronidation by Fatty Acyl-CoAs and Its Plasticity: A Comparative Study in Humans and Rodents Including Chimeric Mice Carrying Human Liver
Nurrochmad, Arief, Ishii, Yuji, Nakanoh, Hitomi, Inoue, Tae, Horie, Toru, Sugihara, Kazumi, Ohta, Shigeru, Taketomi, Akinobu, Maehara, Yoshihiko, Yamada, Hideyuki
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2010)
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2010)
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Journal Article
IN VIVO INDUCTION OF HUMAN CYTOCHROME P450 ENZYMES EXPRESSED IN CHIMERIC MICE WITH HUMANIZED LIVER
KATOH, Miki, MATSUI, Tomohito, NAKAJIMA, Miki, TATENO, Chise, SOENO, Yoshinori, HORIE, Toru, IWASAKI, Kazuhide, YOSHIZATO, Katsutoshi, YOKOI, Tsuyoshi
Published in Drug metabolism and disposition (01.06.2005)
Published in Drug metabolism and disposition (01.06.2005)
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Rectal angiolipoma diagnosed after surgical resection: A case report
Ishizuka, Mitsuru, Nagata, Hitoshi, Takagi, Kazutoshi, Horie, Toru, Abe, Akihito, Kubota, Keiichi
Published in World journal of gastroenterology : WJG (21.01.2007)
Published in World journal of gastroenterology : WJG (21.01.2007)
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Distribution of glucose-6-phosphate dehydrogenase mutations in Southeast Asia
IWAI, Kuni, HIRONO, Akira, SALIM, Abdul M. A, FUJII, Hisaichi, MIWA, Shiro, ISHII, Akira, MATSUOKA, Hiroyuki, KAWAMOTO, Fumihiko, HORIE, Toru, LIN, Khin, TANTULAR, Indah S, DACHLAN, Yoes P, NOTOPURO, Harsono, HIDAYAH, Noor I
Published in Human genetics (01.06.2001)
Published in Human genetics (01.06.2001)
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Characterization of Humanized Liver from Chimeric Mice Using Coumarin as a Human CYP2A6 and Mouse CYP2A5 Probe
Aoki, Kimiko, Kashiwagura, Yasuharu, Horie, Toru, Sato, Hitoshi, Tateno, Chise, Ozawa, Naoki, Yoshizato, Katsutoshi
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2006)
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2006)
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Aldehyde Oxidase-Catalyzed Metabolism of N1-Methylnicotinamide in Vivo and in Vitro in Chimeric Mice with Humanized Liver
KITAMURA, Shigeyuki, NITTA, Kayoko, TAYAMA, Yoshitaka, TANOUE, Chiaki, SUGIHARA, Kazumi, INOUE, Tae, HORIE, Toru, OHTA, Shigeru
Published in Drug metabolism and disposition (01.07.2008)
Published in Drug metabolism and disposition (01.07.2008)
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Journal Article
Induction of Human CYP1A2 and CYP3A4 in Primary Culture of Hepatocytes from Chimeric Mice with Humanized Liver
Nishimura, Masuhiro, Yokoi, Tsuyoshi, Tateno, Chise, Kataoka, Miho, Takahashi, Eiji, Horie, Toru, Yoshizato, Katsutoshi, Naito, Shinsaku
Published in Drug metabolism and pharmacokinetics (2005)
Published in Drug metabolism and pharmacokinetics (2005)
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Journal Article
Inflammation-Based Prognostic Score Is a Novel Predictor of Postoperative Outcome in Patients With Colorectal Cancer
ISHIZUKA, Mitsuru, NAGATA, Hitoshi, TAKAGI, Kazutoshi, HORIE, Toru, KUBOTA, Keiichi
Published in Annals of surgery (01.12.2007)
Published in Annals of surgery (01.12.2007)
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Conference Proceeding
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Total Colectomy Improves Altered Distribution of Regulatory T Cells in Patients with Ulcerative Colitis
Furihata, Makoto, Sawada, Tokihiko, Okada, Toshie, Ishizuka, Mitsuru, Horie, Toru, Takagi, Kazutoshi, Nagata, Hitoshi, Kubota, Keiichi
Published in World journal of surgery (01.04.2006)
Published in World journal of surgery (01.04.2006)
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