MicroRNA-451 Exacerbates Lipotoxicity in Cardiac Myocytes and High-Fat Diet-Induced Cardiac Hypertrophy in Mice Through Suppression of the LKB1/AMPK Pathway
Kuwabara, Yasuhide, Horie, Takahiro, Baba, Osamu, Watanabe, Shin, Nishiga, Masataka, Usami, Shunsuke, Izuhara, Masayasu, Nakao, Tetsushi, Nishino, Tomohiro, Otsu, Kinya, Kita, Toru, Kimura, Takeshi, Ono, Koh
Published in Circulation research (16.01.2015)
Published in Circulation research (16.01.2015)
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Journal Article
Long Non-Coding RNAs as Key Regulators of Cardiovascular Diseases
Ono, Koh, Kuwabara, Yasuhide, Horie, Takahiro, Kimura, Takeshi
Published in Circulation Journal (2018)
Published in Circulation Journal (2018)
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Journal Article
MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo
Horie, Takahiro, Ono, Koh, Horiguchi, Masahito, Nishi, Hitoo, Nakamura, Tomoyuki, Nagao, Kazuya, Kinoshita, Minako, Kuwabara, Yasuhide, Marusawa, Hiroyuki, Iwanaga, Yoshitaka, Hasegawa, Koji, Yokode, Masayuki, Kimura, Takeshi, Kita, Toru
Published in Proceedings of the National Academy of Sciences - PNAS (05.10.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (05.10.2010)
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Journal Article
MicroRNA-33 Controls Adaptive Fibrotic Response in the Remodeling Heart by Preserving Lipid Raft Cholesterol
Nishiga, Masataka, Horie, Takahiro, Kuwabara, Yasuhide, Nagao, Kazuya, Baba, Osamu, Nakao, Tetsushi, Nishino, Tomohiro, Hakuno, Daihiko, Nakashima, Yasuhiro, Nishi, Hitoo, Nakazeki, Fumiko, Ide, Yuya, Koyama, Satoshi, Kimura, Masahiro, Hanada, Ritsuko, Nakamura, Tomoyuki, Inada, Tsukasa, Hasegawa, Koji, Conway, Simon J, Kita, Toru, Kimura, Takeshi, Ono, Koh
Published in Circulation research (03.03.2017)
Published in Circulation research (03.03.2017)
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Journal Article
Functional non‐coding RNAs in vascular diseases
Ono, Koh, Horie, Takahiro, Baba, Osamu, Kimura, Masahiro, Tsuji, Shuhei, Rodriguez, Randolph Ruiz, Miyagawa, Sawa, Kimura, Takeshi
Published in The FEBS journal (01.11.2021)
Published in The FEBS journal (01.11.2021)
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Journal Article
MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice
Horie, Takahiro, Nishino, Tomohiro, Baba, Osamu, Kuwabara, Yasuhide, Nakao, Tetsushi, Nishiga, Masataka, Usami, Shunsuke, Izuhara, Masayasu, Sowa, Naoya, Yahagi, Naoya, Shimano, Hitoshi, Matsumura, Shigenobu, Inoue, Kazuo, Marusawa, Hiroyuki, Nakamura, Tomoyuki, Hasegawa, Koji, Kume, Noriaki, Yokode, Masayuki, Kita, Toru, Kimura, Takeshi, Ono, Koh
Published in Nature communications (03.12.2013)
Published in Nature communications (03.12.2013)
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Journal Article
CRISPR-Cas9-guided amplification-free genomic diagnosis for familial hypercholesterolemia using nanopore sequencing
Xu, Sijia, Shiomi, Hiroki, Yamashita, Yugo, Koyama, Satoshi, Horie, Takahiro, Baba, Osamu, Kimura, Masahiro, Nakashima, Yasuhiro, Sowa, Naoya, Hasegawa, Koji, Suzuki, Ayako, Suzuki, Yutaka, Kimura, Takeshi, Ono, Koh
Published in PloS one (20.03.2024)
Published in PloS one (20.03.2024)
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Journal Article
Genetic Ablation of MicroRNA-33 Attenuates Inflammation and Abdominal Aortic Aneurysm Formation via Several Anti-Inflammatory Pathways
Nakao, Tetsushi, Horie, Takahiro, Baba, Osamu, Nishiga, Masataka, Nishino, Tomohiro, Izuhara, Masayasu, Kuwabara, Yasuhide, Nishi, Hitoo, Usami, Shunsuke, Nakazeki, Fumiko, Ide, Yuya, Koyama, Satoshi, Kimura, Masahiro, Sowa, Naoya, Ohno, Satoko, Aoki, Hiroki, Hasagawa, Koji, Sakamoto, Kazuhisa, Minatoya, Kenji, Kimura, Takeshi, Ono, Koh
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2017)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2017)
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Journal Article
MicroRNA-33a/b in Lipid Metabolism: Novel “Thrifty” Models
Ono, Koh, Horie, Takahiro, Nishino, Tomohiro, Baba, Osamu, Kuwabara, Yasuhide, Yokode, Masayuki, Kita, Toru, Kimura, Takeshi
Published in Circulation Journal (2015)
Published in Circulation Journal (2015)
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Journal Article
Development of a Patient-Derived Induced Pluripotent Stem Cell Model for the Investigation of SCN5A-D1275N-Related Cardiac Sodium Channelopathy
Hayano, Mamoru, Makiyama, Takeru, Kamakura, Tsukasa, Watanabe, Hiroshi, Sasaki, Kenichi, Funakoshi, Shunsuke, Wuriyanghai, Yimin, Nishiuchi, Suguru, Harita, Takeshi, Yamamoto, Yuta, Kohjitani, Hirohiko, Hirose, Sayako, Yokoi, Fumika, Chen, Jiarong, Baba, Osamu, Horie, Takahiro, Chonabayashi, Kazuhisa, Ohno, Seiko, Toyoda, Futoshi, Yoshida, Yoshinori, Ono, Koh, Horie, Minoru, Kimura, Takeshi
Published in Circulation Journal (2017)
Published in Circulation Journal (2017)
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Journal Article
MicroRNA‐33 Deficiency Reduces the Progression of Atherosclerotic Plaque in ApoE−/− Mice
Horie, Takahiro, Baba, Osamu, Kuwabara, Yasuhide, Chujo, Yoshimasa, Watanabe, Shin, Kinoshita, Minako, Horiguchi, Masahito, Nakamura, Tomoyuki, Chonabayashi, Kazuhisa, Hishizawa, Masakatsu, Hasegawa, Koji, Kume, Noriaki, Yokode, Masayuki, Kita, Toru, Kimura, Takeshi, Ono, Koh
Published in Journal of the American Heart Association (01.12.2012)
Published in Journal of the American Heart Association (01.12.2012)
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Journal Article
microRNA-33 maintains adaptive thermogenesis via enhanced sympathetic nerve activity
Horie, Takahiro, Nakao, Tetsushi, Miyasaka, Yui, Nishino, Tomohiro, Matsumura, Shigenobu, Nakazeki, Fumiko, Ide, Yuya, Kimura, Masahiro, Tsuji, Shuhei, Rodriguez, Randolph Ruiz, Watanabe, Toshimitsu, Yamasaki, Tomohiro, Xu, Sijia, Otani, Chiharu, Miyagawa, Sawa, Matsushita, Kazuki, Sowa, Naoya, Omori, Aoi, Tanaka, Jin, Nishimura, Chika, Nishiga, Masataka, Kuwabara, Yasuhide, Baba, Osamu, Watanabe, Shin, Nishi, Hitoo, Nakashima, Yasuhiro, Picciotto, Marina R., Inoue, Haruhisa, Watanabe, Dai, Nakamura, Kazuhiro, Sasaki, Tsutomu, Kimura, Takeshi, Ono, Koh
Published in Nature communications (16.02.2021)
Published in Nature communications (16.02.2021)
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Journal Article
Regulation of Adipocyte Differentiation by Activation of Serotonin (5-HT) Receptors 5-HT2AR and 5-HT2CR and Involvement of MicroRNA-448-Mediated Repression of KLF5
Kinoshita, Minako, Ono, Koh, Horie, Takahiro, Nagao, Kazuya, Nishi, Hitoo, Kuwabara, Yasuhide, Takanabe-Mori, Rieko, Hasegawa, Koji, Kita, Toru, Kimura, Takeshi
Published in Molecular endocrinology (Baltimore, Md.) (01.10.2010)
Published in Molecular endocrinology (Baltimore, Md.) (01.10.2010)
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Journal Article
MicroRNA-15b Modulates Cellular ATP Levels and Degenerates Mitochondria via Arl2 in Neonatal Rat Cardiac Myocytes
Nishi, Hitoo, Ono, Koh, Iwanaga, Yoshitaka, Horie, Takahiro, Nagao, Kazuya, Takemura, Genzou, Kinoshita, Minako, Kuwabara, Yasuhide, Mori, Rieko Takanabe, Hasegawa, Koji, Kita, Toru, Kimura, Takeshi
Published in The Journal of biological chemistry (12.02.2010)
Published in The Journal of biological chemistry (12.02.2010)
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Journal Article
MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes
Horie, Takahiro, Ono, Koh, Nishi, Hitoo, Iwanaga, Yoshitaka, Nagao, Kazuya, Kinoshita, Minako, Kuwabara, Yasuhide, Takanabe, Rieko, Hasegawa, Koji, Kita, Toru, Kimura, Takeshi
Published in Biochemical and biophysical research communications (13.11.2009)
Published in Biochemical and biophysical research communications (13.11.2009)
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Journal Article
SREBF1/MicroRNA-33b Axis Exhibits Potent Effect on Unstable Atherosclerotic Plaque Formation In Vivo
Nishino, Tomohiro, Horie, Takahiro, Baba, Osamu, Sowa, Naoya, Hanada, Ritsuko, Kuwabara, Yasuhide, Nakao, Tetsushi, Nishiga, Masataka, Nishi, Hitoo, Nakashima, Yasuhiro, Nakazeki, Fumiko, Ide, Yuya, Koyama, Satoshi, Kimura, Masahiro, Nagata, Manabu, Yoshida, Kazumichi, Takagi, Yasushi, Nakamura, Tomoyuki, Hasegawa, Koji, Miyamoto, Susumu, Kimura, Takeshi, Ono, Koh
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2018)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2018)
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Journal Article
Prevention of neointimal formation using miRNA-126-containing nanoparticle-conjugated stents in a rabbit model
Izuhara, Masayasu, Kuwabara, Yasuhide, Saito, Naritatsu, Yamamoto, Erika, Hakuno, Daihiko, Nakashima, Yasuhiro, Horie, Takahiro, Baba, Osamu, Nishiga, Masataka, Nakao, Tetsushi, Nishino, Tomohiro, Nakazeki, Fumiko, Ide, Yuya, Kimura, Masahiro, Kimura, Takeshi, Ono, Koh
Published in PloS one (02.03.2017)
Published in PloS one (02.03.2017)
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Journal Article
Overview of the 84th Annual Scientific Meeting of the Japanese Circulation Society ― Change Practice!
Ono, Koh, Shizuta, Satoshi, Yamamoto, Erika, Saito, Naritatsu, Ozasa, Neiko, Kato, Takao, Kato, Eri, Horie, Takahiro, Tazaki, Junichi, Shiomi, Hiroki, Watanabe, Shin, Watanabe, Hirotoshi, Yamashita, Yugo, Yoshikawa, Yusuke, Kinoshita, Hideyuki, Makiyama, Takeru, Yoshida, Yoshinori, Ashida, Noboru, Nakagawa, Yasuaki, Nakashima, Yasuhiro, Baba, Osamu, Kohjitani, Hirohiko, Kimura, Masahiro, Inazumi, Hideaki, Yoshizawa, Takashi, Komasa, Akihiro, Kimura, Takeshi
Published in Circulation Journal (25.02.2021)
Published in Circulation Journal (25.02.2021)
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Journal Article
Inhibition of microRNA-33b specifically ameliorates abdominal aortic aneurysm formation via suppression of inflammatory pathways
Yamasaki, Tomohiro, Horie, Takahiro, Koyama, Satoshi, Nakao, Tetsushi, Baba, Osamu, Kimura, Masahiro, Sowa, Naoya, Sakamoto, Kazuhisa, Yamazaki, Kazuhiro, Obika, Satoshi, Kasahara, Yuuya, Kotera, Jun, Oka, Kozo, Fujita, Ryo, Sasaki, Takashi, Takemiya, Akihiro, Hasegawa, Koji, Minatoya, Kenji, Kimura, Takeshi, Ono, Koh
Published in Scientific reports (14.07.2022)
Published in Scientific reports (14.07.2022)
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Journal Article
KUS121, a VCP modulator, has an ameliorating effect on acute and chronic heart failure without calcium loading via maintenance of intracellular ATP levels
Tsuji, Shuhei, Otani, Chiharu, Horie, Takahiro, Watanabe, Shin, Baba, Osamu, Sowa, Naoya, Ide, Yuya, Kashiwa, Asami, Makiyama, Takeru, Imai, Hirohiko, Nakashima, Yasuhiro, Yamasaki, Tomohiro, Xu, Sijia, Matsushita, Kazuki, Suzuki, Keita, Zou, Fuquan, Kume, Eitaro, Hasegawa, Koji, Kimura, Takeshi, Kakizuka, Akira, Ono, Koh
Published in Biomedicine & pharmacotherapy (01.01.2024)
Published in Biomedicine & pharmacotherapy (01.01.2024)
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Journal Article