Clinical validation of the novel HDAC6 radiotracer [18F]EKZ-001 in the human brain
Koole, Michel, Van Weehaeghe, Donatienne, Serdons, Kim, Herbots, Marissa, Cawthorne, Christopher, Celen, Sofie, Schroeder, Frederick A., Hooker, Jacob M., Bormans, Guy, de Hoon, Jan, Kranz, Janice E., Van Laere, Koen, Gilbert, Tonya M.
Published in European journal of nuclear medicine and molecular imaging (01.02.2021)
Published in European journal of nuclear medicine and molecular imaging (01.02.2021)
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Minimally invasive quantification of cerebral P2X7R occupancy using dynamic [18F]JNJ-64413739 PET and MRA-driven image derived input function
Mertens, Nathalie, Schmidt, Mark E., Hijzen, Anja, Van Weehaeghe, Donatienne, Ravenstijn, Paulien, Depre, Marleen, de Hoon, Jan, Van Laere, Koen, Koole, Michel
Published in Scientific reports (09.08.2021)
Published in Scientific reports (09.08.2021)
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Tramadol and O-Desmethyl Tramadol Clearance Maturation and Disposition in Humans: A Pooled Pharmacokinetic Study
Allegaert, Karel, Holford, Nick, Anderson, Brian J., Holford, Sam, Stuber, Frank, Rochette, Alain, Trocóniz, Iñaki F., Beier, Horst, de Hoon, Jan N., Pedersen, Rasmus S., Stamer, Ulrike
Published in Clinical pharmacokinetics (01.02.2015)
Published in Clinical pharmacokinetics (01.02.2015)
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Pharmacokinetics of Drugs in Neonates: Pattern Recognition Beyond Compound Specific Observations
Smits, Anne, Kulo, Aida, de Hoon, Jan N, Allegaert, Karel
Published in Current pharmaceutical design (27.02.2012)
Published in Current pharmaceutical design (27.02.2012)
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Preclinical Safety Evaluation and Human Dosimetry of [18F]MK-6240, a Novel PET Tracer for Imaging Neurofibrillary Tangles
Koole, Michel, Lohith, Talakad G., Valentine, John L., Bennacef, Idriss, Declercq, Ruben, Reynders, Tom, Riffel, Kerry, Celen, Sofie, Serdons, Kim, Bormans, Guy, Ferry-Martin, Sandrine, Laroque, Philippe, Walji, Abbas, Hostetler, Eric D., Briscoe, Richard J., de Hoon, Jan, Sur, Cyrille, Van Laere, Koen, Struyk, Arie
Published in Molecular imaging and biology (01.02.2020)
Published in Molecular imaging and biology (01.02.2020)
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Functional Analysis of TRPA1, TRPM3, and TRPV1 Channels in Human Dermal Arteries and Their Role in Vascular Modulation
Rivera-Mancilla, Eduardo, Al-Hassany, Linda, Marynissen, Heleen, Bamps, Dorien, Garrelds, Ingrid M, Cornette, Jérôme, Danser, A H Jan, Villalón, Carlos M, de Hoon, Jan N, MaassenVanDenBrink, Antoinette
Published in Pharmaceuticals (Basel, Switzerland) (25.01.2024)
Published in Pharmaceuticals (Basel, Switzerland) (25.01.2024)
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Human biodistribution and dosimetry of [11C]-UCB-J, a PET radiotracer for imaging synaptic density
Cawthorne, Christopher, Maguire, Paul, Mercier, Joel, Sciberras, David, Serdons, Kim, Bormans, Guy, de Hoon, Jan, Van Laere, Koen, Koole, Michel
Published in EJNMMI physics (23.04.2021)
Published in EJNMMI physics (23.04.2021)
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Pharmacokinetic and pharmacodynamic assessments of atogepant in healthy male adults: Results from phase 1 studies
Boinpally, Ramesh, Depré, Marleen, Van Lancker, Griet, Dockendorf, Marissa F, Bondiskey, Phung, Denef, Jean-Francois, Reynders, Tom, Matthews, Catherine Zhou, Min, K Chris, Xu, Jialin, Trugman, Joel M, de Hoon, Jan
Published in Cephalalgia reports (01.01.2023)
Published in Cephalalgia reports (01.01.2023)
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TRP Channel Cooperation for Nociception: Therapeutic Opportunities
Bamps, Dorien, Vriens, Joris, de Hoon, Jan, Voets, Thomas
Published in Annual review of pharmacology and toxicology (06.01.2021)
Published in Annual review of pharmacology and toxicology (06.01.2021)
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Interim Results of a Phase 1–2a Trial of Ad26.COV2.S Covid-19 Vaccine
Sadoff, Jerald, Le Gars, Mathieu, Shukarev, Georgi, Heerwegh, Dirk, Truyers, Carla, de Groot, Anne M, Stoop, Jeroen, Tete, Sarah, Van Damme, Wim, Leroux-Roels, Isabel, Berghmans, Pieter-Jan, Kimmel, Murray, Van Damme, Pierre, de Hoon, Jan, Smith, William, Stephenson, Kathryn E, De Rosa, Stephen C, Cohen, Kristen W, McElrath, M. Juliana, Cormier, Emmanuel, Scheper, Gert, Barouch, Dan H, Hendriks, Jenny, Struyf, Frank, Douoguih, Macaya, Van Hoof, Johan, Schuitemaker, Hanneke
Published in New England Journal of Medicine (13.05.2021)
Published in New England Journal of Medicine (13.05.2021)
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Maturational pharmacokinetics of single intravenous bolus of propofol
ALLEGAERT, KAREL, HOON, JAN DE, VERBESSELT, RENE, NAULAERS, GUNNAR, MURAT, ISABELLE
Published in Pediatric anesthesia (01.11.2007)
Published in Pediatric anesthesia (01.11.2007)
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Acute effects of sumatriptan on aortic blood pressure, stiffness, and pressure waveform
Vanmolkot, Floris H M, de Hoon, Jan N J M
Published in Clinical pharmacology and therapeutics (01.07.2006)
Published in Clinical pharmacology and therapeutics (01.07.2006)
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Pharmacokinetics of drugs in neonates: pattern recognition beyond compound specific observations
Smits, Anne, Kulo, Aida, de Hoon, Jan N, Allegaert, Karel
Published in Current pharmaceutical design (01.07.2012)
Published in Current pharmaceutical design (01.07.2012)
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Renal Side Effects of Non-Steroidal Anti-Inflammatory Drugs in Neonates
Allegaert, Karel, De Hoon, Jan, Debeer, Anne, Gewillig, Marc
Published in Pharmaceuticals (03.02.2010)
Published in Pharmaceuticals (03.02.2010)
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Book Review
RVCL-S and CADASIL display distinct impaired vascular function
de Boer, Irene, Stam, Anine H, Buntinx, Linde, Zielman, Ronald, van der Steen, Iris, van den Maagdenberg, Arn M J M, de Koning, Eelco J P, Ferrari, Michel D, de Hoon, Jan N, Terwindt, Gisela M
Published in Neurology (04.09.2018)
Published in Neurology (04.09.2018)
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Translational Pharmacodynamics of Calcitonin Gene-Related Peptide Monoclonal Antibody LY2951742 in a Capsaicin-Induced Dermal Blood Flow Model
Vermeersch, Steve, Benschop, Robert J, Van Hecken, Anne, Monteith, David, Wroblewski, Victor J, Grayzel, David, de Hoon, Jan, Collins, Emily C
Published in The Journal of pharmacology and experimental therapeutics (01.09.2015)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2015)
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Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the CGRP Binding Monoclonal Antibody LY2951742 (Galcanezumab) in Healthy Volunteers
Monteith, David, Collins, Emily C, Vandermeulen, Corinne, Van Hecken, Anne, Raddad, Eyas, Scherer, Joel C, Grayzel, David, Schuetz, Thomas J, de Hoon, Jan
Published in Frontiers in pharmacology (17.10.2017)
Published in Frontiers in pharmacology (17.10.2017)
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