Search Results - "HONGU MITSUYA" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery of 2-[(E)-2-(7-Fluoro-3-methylquinoxalin-2-yl)vinyl]-6-pyrrolidin-1-yl-N-(tetrahydro-2H-pyran-4-yl)pyrimidin-4-amine Hydrochloride as a Highly Selective PDE10A Inhibitor

Discovery of 2-[(E)-2-(7-Fluoro-3-methylquinoxalin-2-yl)vinyl]-6-pyrrolidin-1-yl-N-(tetrahydro-2H-pyran-4-yl)pyrimidin-4-amine Hydrochloride as a Highly Selective PDE10A Inhibitor

by Kadoh, Yoichi, Miyoshi, Haruko, Matsumura, Takehiko, Tanaka, Yoshihito, Hongu, Mitsuya, Kimura, Mayumi, Takedomi, Kei, Omori, Kenji, Kotera, Jun, Sasaki, Takashi, Kobayashi, Tamaki, Taniguchi, Hiroyuki, Watanabe, Yumi, Kojima, Koki, Sakamoto, Toshiaki, Himiyama, Toshiyuki, Kawanishi, Eiji
Published in Chemical & pharmaceutical bulletin (2018)

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Journal Article

Na+-Glucose Cotransporter (SGLT) Inhibitors as Antidiabetic Agents. 4. Synthesis and Pharmacological Properties of 4‘-Dehydroxyphlorizin Derivatives Substituted on the B Ring

Na+-Glucose Cotransporter (SGLT) Inhibitors as Antidiabetic Agents. 4. Synthesis and Pharmacological Properties of 4‘-Dehydroxyphlorizin Derivatives Substituted on the B Ring

by Tsujihara, Kenji, Hongu, Mitsuya, Saito, Kunio, Kawanishi, Hiroyuki, Kuriyama, Kayoko, Matsumoto, Mamoru, Oku, Akira, Ueta, Kiichiro, Tsuda, Minoru, Saito, Akira
Published in Journal of medicinal chemistry (30.12.1999)

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Journal Article

Discovery of Canagliflozin, a Novel C-Glucoside with Thiophene Ring, as Sodium-Dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes Mellitus

Discovery of Canagliflozin, a Novel C-Glucoside with Thiophene Ring, as Sodium-Dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes Mellitus

by Nomura, Sumihiro, Sakamaki, Shigeki, Hongu, Mitsuya, Kawanishi, Eiji, Koga, Yuichi, Sakamoto, Toshiaki, Yamamoto, Yasuo, Ueta, Kiichiro, Kimata, Hirotaka, Nakayama, Keiko, Tsuda-Tsukimoto, Minoru
Published in Journal of medicinal chemistry (09.09.2010)

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Journal Article

Na+-glucose cotransporter inhibitors as antidiabetics. I. Synthesis and pharmacological properties of 4'-dehydroxyphlorizin derivatives based on a new concept

Na+-glucose cotransporter inhibitors as antidiabetics. I. Synthesis and pharmacological properties of 4'-dehydroxyphlorizin derivatives based on a new concept

by TSUJIHARA, K, HONGU, M, SAITO, K, INAMASU, M, ARAKAWA, K, OKU, A, MATSUMOTO, M
Published in Chemical & pharmaceutical bulletin (1996)

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Journal Article

Solid-Liquid Phase Transfer Catalyzed Novel Glycosylation Reaction of Phenols

Solid-Liquid Phase Transfer Catalyzed Novel Glycosylation Reaction of Phenols

by Hongu, Mitsuya, Saito, Kunio, Tsujihara, Kenji
Published in Synthetic communications (01.08.1999)

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Journal Article

Discovery of a pyrazolo[1,5-a]pyrimidine derivative (MT-3014) as a highly selective PDE10A inhibitor via core structure transformation from the stilbene moiety

Discovery of a pyrazolo[1,5-a]pyrimidine derivative (MT-3014) as a highly selective PDE10A inhibitor via core structure transformation from the stilbene moiety

by Koizumi, Yuuki, Tanaka, Yoshihito, Matsumura, Takehiko, Kadoh, Yoichi, Miyoshi, Haruko, Hongu, Mitsuya, Takedomi, Kei, Kotera, Jun, Sasaki, Takashi, Taniguchi, Hiroyuki, Watanabe, Yumi, Takakuwa, Misae, Kojima, Koki, Baba, Nobuyuki, Nakamura, Itsuko, Kawanishi, Eiji
Published in Bioorganic & medicinal chemistry (01.08.2019)

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Journal Article

Na+-Glucose Cotransporter Inhibitors as Antidiabetic Agents. II. Synthesis and Structure-Activity Relationships of 4'-Dehydroxyphlorizin Derivatives

Na+-Glucose Cotransporter Inhibitors as Antidiabetic Agents. II. Synthesis and Structure-Activity Relationships of 4'-Dehydroxyphlorizin Derivatives

by HONGU, Mitsuya, TANAKA, Takashi, FUNAMI, Nobuyuki, SAITO, Kunio, ARAKAWA, Kenji, MATSUMOTO, Mamoru, TSUJIHARA, Kenji
Published in Chemical & pharmaceutical bulletin (01.01.1998)

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Journal Article

C-Glucosides with heteroaryl thiophene as novel sodium-dependent Cross Mark glucose cotransporter 2 inhibitors

C-Glucosides with heteroaryl thiophene as novel sodium-dependent Cross Mark glucose cotransporter 2 inhibitors

by Koga, Yuichi, Sakamaki, Shigeki, Hongu, Mitsuya, Kawanishi, Eiji, Sakamoto, Toshiaki, Yamamoto, Yasuo, Kimata, Hirotaka, Nakayama, Keiko, Kuriyama, Chiaki, Matsushita, Yasuaki, Ueta, Kiichiro, Tsuda-Tsukimoto, Minoru, Nomura, Sumihiro
Published in Bioorganic & medicinal chemistry (01.09.2013)

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Journal Article

Na+-Glucose Cotransporter Inhibitors as Antidiabetic Agents. III. Synthesis and Pharmacological Properties of 4'-Dehydroxyphlorizin Derivatives Modified at the OH Groups of the Glucose Moiety

Na+-Glucose Cotransporter Inhibitors as Antidiabetic Agents. III. Synthesis and Pharmacological Properties of 4'-Dehydroxyphlorizin Derivatives Modified at the OH Groups of the Glucose Moiety

by HONGU, Mitsuya, FUNAMI, Nobuyuki, TAKAHASHI, Youichi, SAITO, Kunio, ARAKAWA, Kenji, MATSUMOTO, Mamoru, YAMAKITA, Hirokazu, TSUJIHARA, Kenji
Published in Chemical & pharmaceutical bulletin (1998)

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Journal Article

C-Glucosides with heteroaryl thiophene as novel sodium-dependent glucose cotransporter 2 inhibitors

C-Glucosides with heteroaryl thiophene as novel sodium-dependent glucose cotransporter 2 inhibitors

by Koga, Yuichi, Sakamaki, Shigeki, Hongu, Mitsuya, Kawanishi, Eiji, Sakamoto, Toshiaki, Yamamoto, Yasuo, Kimata, Hirotaka, Nakayama, Keiko, Kuriyama, Chiaki, Matsushita, Yasuaki, Ueta, Kiichiro, Tsuda-Tsukimoto, Minoru, Nomura, Sumihiro
Published in Bioorganic & medicinal chemistry (01.09.2013)

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Journal Article

PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE AS PDE10 INHIBITORS

PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE AS PDE10 INHIBITORS

by TANAKA YOSHIHITO, HONGU MITSUYA, KAWANISHI EIJI
Year of Publication 20.12.2012

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Patent

Synthesis and Biological Activity of O-Alkyl-3-N-aminoacyloxymethyl-5-fluoro-2'-deoxyuridine Derivatives

Synthesis and Biological Activity of O-Alkyl-3-N-aminoacyloxymethyl-5-fluoro-2'-deoxyuridine Derivatives

by HARADA, Naoyuki, HONGU, Mitsuya, KAWAGUCHI, Takayuki, OHOHASHI, Motoaki, ODA, Kouji, HASHIYAMA, Tomiki, TSUJIHARA, Kenji
Published in Chemical & pharmaceutical bulletin (1996)

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Journal Article

PROCESS FOR THE PREPARATION OF COMPOUNDS USEFUL AS INHIBITORS OF SGLT

PROCESS FOR THE PREPARATION OF COMPOUNDS USEFUL AS INHIBITORS OF SGLT

by KOGA YUICHI, MEHRMAN STEVEN, SCOTT LORRAINE, WELLS KENNETH M, HONGU MITSUYA, NOMURA SUMIHIRO, CHISHOLM MAUREEN, ZHANG PLASKET FAN, ABDEL MAGID AHMED F
Year of Publication 05.07.2010

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Patent

HYPOGLYCEMIC AGENT

HYPOGLYCEMIC AGENT

by ARAKWA, KENJI, TSUJIHARA, KENJI, HONGU, MITSUYA, FUNAMI, NOBUYUKI, INAMASU, MASANORI
Year of Publication 02.08.1999

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Patent

Compostos de pirazolopirimidina, composições relacionadas e seu uso como inibidores de pde10

Compostos de pirazolopirimidina, composições relacionadas e seu uso como inibidores de pde10

by Kawanishi Eiji, Tanaka Yoshihito, Hongu Mitsuya
Year of Publication 14.12.2021

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Patent

PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE AS PDE10 INHIBITORS

PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE AS PDE10 INHIBITORS

by KAWANISHI, EIJI, TANAKA, YOSHIHITO, HONGU, MITSUYA
Year of Publication 15.04.2015

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Patent

Pyrazolopyrimidine compounds and their use as PDE10 inhibitors

Pyrazolopyrimidine compounds and their use as PDE10 inhibitors

by TANAKA YOSHIHITO, HONGU MITSUYA, KAWANISHI EIJI
Year of Publication 03.03.2015

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Patent

PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE AS PDE10 INHIBITORS

PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE AS PDE10 INHIBITORS

by KAWANISHI, EIJI, TANAKA, YOSHIHITO, HONGU, MITSUYA
Year of Publication 30.12.2014

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Patent

Pyrazolopyrimidine compounds and their use as PDE10 inhibitors

Pyrazolopyrimidine compounds and their use as PDE10 inhibitors

by KAWANISHI, EIJI, TANAKA, YOSHIHITO, HONGU, MITSUYA
Year of Publication 19.12.2013

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Patent

NOVEL SGLT INHIBITORS

NOVEL SGLT INHIBITORS

by NOMURA, SUMIHIRO, HONGU, MITSUYA
Year of Publication 15.04.2009

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Patent

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