Lysosomal Sequestration of Sunitinib: A Novel Mechanism of Drug Resistance
GOTINK, Kristy J, BROXTERMAN, Henk J, GRIFFIOEN, Arjan W, ASSARAF, Yehuda G, PILI, Roberto, PETERS, Godefridus J, VERHEUL, Henk M. W, LABOTS, Mariette, DE HAAS, Richard R, DEKKER, Henk, HONEYWELL, Richard J, RUDEK, Michelle A, BEEREPOOT, Laurens V, MUSTERS, René J, JANSEN, Gerrit
Published in Clinical cancer research (01.12.2011)
Published in Clinical cancer research (01.12.2011)
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Journal Article
Coexisting Molecular Determinants of Acquired Oxaliplatin Resistance in Human Colorectal and Ovarian Cancer Cell Lines
Noordhuis, Paul, Laan, Adrianus C, van de Born, Kasper, Honeywell, Richard J, Peters, Godefridus J
Published in International journal of molecular sciences (24.07.2019)
Published in International journal of molecular sciences (24.07.2019)
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Journal Article
RX-3117 (Fluorocyclopentenyl-Cytosine)-Mediated Down-Regulation of DNA Methyltransferase 1 Leads to Protein Expression of Tumor-Suppressor Genes and Increased Functionality of the Proton-Coupled Folate Carrier
Sarkisjan, Dzjemma, Julsing, Joris R, El Hassouni, Btissame, Honeywell, Richard J, Kathmann, Ietje, Matherly, Larry H, Lee, Young B, Kim, Deog J, Peters, Godefridus J
Published in International journal of molecular sciences (14.04.2020)
Published in International journal of molecular sciences (14.04.2020)
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Journal Article
DNA-bound platinum is the major determinant of cisplatin sensitivity in head and neck squamous carcinoma cells
Martens-de Kemp, Sanne R, Dalm, Simone U, Wijnolts, Fiona M J, Brink, Arjen, Honeywell, Richard J, Peters, Godefridus J, Braakhuis, Boudewijn J M, Brakenhoff, Ruud H
Published in PloS one (17.04.2013)
Published in PloS one (17.04.2013)
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Journal Article
Cross-resistance to clinically used tyrosine kinase inhibitors sunitinib, sorafenib and pazopanib
Gotink, Kristy J., Rovithi, Maria, de Haas, Richard R., Honeywell, Richard J., Dekker, Henk, Poel, Dennis, Azijli, Kaamar, Peters, Godefridus J., Broxterman, Henk J., Verheul, Henk M. W.
Published in Cellular oncology (Dordrecht) (01.04.2015)
Published in Cellular oncology (Dordrecht) (01.04.2015)
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Journal Article
The prognostic impact of circulating miRNAs in patients with advanced esophagogastric cancer during palliative chemotherapy
van Zweeden, Annette A., Opperman, Roza C.M., Honeywell, Richard J., Peters, Godefridus J., Verheul, Henk M.W., van der Vliet, Hans J., Poel, Dennis
Published in Cancer treatment and research communications (2021)
Published in Cancer treatment and research communications (2021)
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Journal Article
Acquired tumor cell resistance to sunitinib causes resistance in a HT-29 human colon cancer xenograft mouse model without affecting sunitinib biodistribution or the tumor microvasculature
Gotink, Kristy J, Broxterman, Henk J, Honeywell, Richard J, Dekker, Henk, de Haas, Richard R, Miles, Kiersten M, Adelaiye, Remi, Griffioen, Arjan W, Peters, Godefridus J, Pili, Roberto, Verheul, Henk M W
Published in Oncoscience (15.12.2014)
Published in Oncoscience (15.12.2014)
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Journal Article
Crizotinib Inhibits Metabolic Inactivation of Gemcitabine in c-Met―driven Pancreatic Carcinoma
AVAN, Amir, CARETTI, Viola, VERHEUL, Henk M, SCHUURHUIS, Gerrit-Jan, BOGGI, Ugo, PETERS, Godefridus J, WÜRDINGER, Thomas, GIOVANNETTI, Elisa, FUNEL, Niccola, GALVANI, Elena, MAFTOUH, Mina, HONEYWELL, Richard J, LAGERWEIJ, Tonny, VAN TELLINGEN, Olaf, CAMPANI, Daniela, FUCHS, Dieter
Published in Cancer research (Chicago, Ill.) (15.11.2013)
Published in Cancer research (Chicago, Ill.) (15.11.2013)
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Journal Article
Tumor Drug Concentration and Phosphoproteomic Profiles After Two Weeks of Treatment With Sunitinib in Patients with Newly Diagnosed Glioblastoma
van Linde, Myra E, Labots, Mariette, Brahm, Cyrillo G, Hovinga, Koos E, De Witt Hamer, Philip C, Honeywell, Richard J, de Goeij-de Haas, Richard, Henneman, Alex A, Knol, Jaco C, Peters, Godefridus J, Dekker, Henk, Piersma, Sander R, Pham, Thang V, Vandertop, William P, Jiménez, Connie R, Verheul, Henk M W
Published in Clinical cancer research (14.04.2022)
Published in Clinical cancer research (14.04.2022)
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Journal Article
Molecular mechanisms involved in the synergistic interaction of the EZH2 inhibitor 3-deazaneplanocin A with gemcitabine in pancreatic cancer cells
Avan, Amir, Crea, Francesco, Paolicchi, Elisa, Funel, Niccola, Galvani, Elena, Marquez, Victor E, Honeywell, Richard J, Danesi, Romano, Peters, Godefridus J, Giovannetti, Elisa
Published in Molecular cancer therapeutics (01.08.2012)
Published in Molecular cancer therapeutics (01.08.2012)
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Journal Article
Inhibition of thymidylate synthase by 2′,2′-difluoro-2′-deoxycytidine (Gemcitabine) and its metabolite 2′,2′-difluoro-2′-deoxyuridine
Honeywell, Richard J., Ruiz van Haperen, Veronique W.T., Veerman, Gijsbert, Smid, Kees, Peters, Godefridus J.
Published in The international journal of biochemistry & cell biology (01.03.2015)
Published in The international journal of biochemistry & cell biology (01.03.2015)
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Journal Article
RX-3117 (fluorocyclopentenyl cytosine): a novel specific antimetabolite for selective cancer treatment
Balboni, Beatrice, El Hassouni, Btissame, Honeywell, Richard J., Sarkisjan, Dzjemma, Giovannetti, Elisa, Poore, Julie, Heaton, Callie, Peterson, Christine, Benaim, Ely, Lee, Young B., Kim, Deog J., Peters, Godefridus J.
Published in Expert opinion on investigational drugs (03.04.2019)
Published in Expert opinion on investigational drugs (03.04.2019)
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Journal Article
Phase I Dose-Escalation Study of Once Weekly or Once Every Two Weeks Administration of High-Dose Sunitinib in Patients With Refractory Solid Tumors
Rovithi, Maria, Gerritse, Sophie L, Honeywell, Richard J, Ten Tije, Albert J, Ruijter, Rita, Peters, Godefridus J, Voortman, Jens, Labots, Mariette, Verheul, Henk M W
Published in Journal of clinical oncology (10.02.2019)
Published in Journal of clinical oncology (10.02.2019)
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Journal Article
Overcoming crizotinib resistance in ALK-rearranged NSCLC with the second-generation ALK-inhibitor ceritinib
Muller, Ittai B, De Langen, Adrianus J, Honeywell, Richard J, Giovannetti, Elisa, Peters, Godefridus J
Published in Expert review of anticancer therapy (01.02.2016)
Published in Expert review of anticancer therapy (01.02.2016)
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Journal Article
Crizotinib sensitizes the erlotinib resistant HCC827GR5 cell line by influencing lysosomal function
Van Der Steen, Nele, Keller, Kaylee, Dekker, Henk, Porcelli, Letizia, Honeywell, Richard J., Van Meerloo, Johan, Musters, René J. P., Kathmann, Ietje, Frampton, Adam E., Liu, Daniel S. K., Ruijtenbeek, Rob, Rolfo, Christian, Pauwels, Patrick, Giovannetti, Elisa, Peters, Godefridus J.
Published in Journal of cellular physiology (01.11.2020)
Published in Journal of cellular physiology (01.11.2020)
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Journal Article
DNA methyltransferases expression in normal tissues and various human cancer cell lines, xenografts and tumors
Honeywell, Richard J, Sarkisjan, Dzjemma, Kristensen, Michael H., de Klerk, Daniel J, Peters, Godefridus J.
Published in Nucleosides, nucleotides & nucleic acids (02.12.2018)
Published in Nucleosides, nucleotides & nucleic acids (02.12.2018)
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