Pharmacological profile of CS-3150, a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist
Arai, Kiyoshi, Homma, Tsuyoshi, Morikawa, Yuka, Ubukata, Naoko, Tsuruoka, Hiyoyuki, Aoki, Kazumasa, Ishikawa, Hirokazu, Mizuno, Makoto, Sada, Toshio
Published in European journal of pharmacology (15.08.2015)
Published in European journal of pharmacology (15.08.2015)
Get full text
Journal Article
Histone demethylase LSD1 deficiency and biological sex: impact on blood pressure and aldosterone production
Huang, Yuefei, Ting, Pei Yee, Yao, Tham M, Homma, Tsuyoshi, Brooks, Danielle, Katayama Rangel, Isis, Adler, Gail K, Romero, Jose R, Williams, Jonathan S, Pojoga, Luminita H, Williams, Gordon H
Published in Journal of endocrinology (01.02.2019)
Published in Journal of endocrinology (01.02.2019)
Get full text
Journal Article
Combined Salt and Caloric Restrictions: Potential Adverse Outcomes
Homma, Tsuyoshi, Homma, Mika, Huang, Yuefei, Mayurasakorn, Korapat, Rodi, Nurul Mahamad, Hamid, Anis Amalina Abdul, Hurwitz, Shelley, Yao, Tham, Adler, Gail K., Pojoga, Luminita H., Williams, Gordon H., Romero, Jose R.
Published in Journal of the American Heart Association (11.10.2017)
Published in Journal of the American Heart Association (11.10.2017)
Get full text
Journal Article
Crystal structure of the mineralocorticoid receptor ligand‐binding domain in complex with a potent and selective nonsteroidal blocker, esaxerenone (CS‐3150)
Takahashi, Mizuki, Ubukata, Osamu, Homma, Tsuyoshi, Asoh, Yusuke, Honzumi, Masatoshi, Hayashi, Noriyuki, Saito, Keiji, Tsuruoka, Hiroyuki, Aoki, Kazumasa, Hanzawa, Hiroyuki
Published in FEBS letters (01.05.2020)
Published in FEBS letters (01.05.2020)
Get full text
Journal Article
Identification of sulfonylpyrimidines as novel selective aldosterone synthase (CYP11B2) inhibitors
Meguro, Masaki, Miyauchi, Satoru, Kanao-Arisumi, Yukiko, Naito, Satoru, Suzuki, Kanae, Inoue, Shinichi, Yamada, Keisuke, Homma, Tsuyoshi, Chiba, Kiyoshi, Nara, Futoshi, Furuzono, Shinji
Published in Bioorganic & medicinal chemistry (15.06.2024)
Published in Bioorganic & medicinal chemistry (15.06.2024)
Get full text
Journal Article
CS-3150, a Novel Nonsteroidal Mineralocorticoid Receptor Antagonist, Shows Preventive and Therapeutic Effects On Renal Injury in Deoxycorticosterone Acetate/Salt-Induced Hypertensive Rats
Arai, Kiyoshi, Morikawa, Yuka, Ubukata, Naoko, Tsuruoka, Hiroyuki, Homma, Tsuyoshi
Published in The Journal of pharmacology and experimental therapeutics (01.09.2016)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2016)
Get full text
Journal Article
Sustained Activation of Guanylate Cyclase-A with TDT, a Natriuretic Peptide Derivative, Exhibits Cardiorenal Protection in Dahl Salt-Sensitive Hypertensive Rats
Oishi, Shohei, Suzuki, Naoko, Hasui, Yuri, Homma, Tsuyoshi, Obana, Masanori, Nagayama, Takahiro, Fujio, Yasushi
Published in The Journal of pharmacology and experimental therapeutics (01.12.2017)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2017)
Get full text
Journal Article
Caloric restriction improves glucose homeostasis, yet increases cardiometabolic risk in caveolin-1-deficient mice
Mayurasakorn, Korapat, Hasanah, Nurul, Homma, Tsuyoshi, Homma, Mika, Rangel, Isis Katayama, Garza, Amanda E., Romero, Jose R., Adler, Gail K., Williams, Gordon H., Pojoga, Luminita H.
Published in Metabolism, clinical and experimental (01.06.2018)
Published in Metabolism, clinical and experimental (01.06.2018)
Get full text
Journal Article
A novel aldosterone synthase inhibitor ameliorates mortality in pressure-overload mice with heart failure
Furuzono, Shinji, Meguro, Masaki, Miyauchi, Satoru, Inoue, Shinichi, Homma, Tsuyoshi, Yamada, Keisuke, Tagawa, Yoh-ichi, Nara, Futoshi, Nagayama, Takahiro
Published in European journal of pharmacology (15.01.2017)
Published in European journal of pharmacology (15.01.2017)
Get full text
Journal Article
4-Anilino-pyrimidine, novel aldosterone synthase (CYP11B2) inhibitors bearing pyrimidine structures
Meguro, Masaki, Miyauchi, Satoru, Kanao, Yukiko, Naito, Satoru, Suzuki, Kanae, Inoue, Shinichi, Yamada, Keisuke, Homma, Tsuyoshi, Chiba, Kiyoshi, Nara, Futoshi, Furuzono, Shinji
Published in Bioorganic & medicinal chemistry letters (01.05.2017)
Published in Bioorganic & medicinal chemistry letters (01.05.2017)
Get full text
Journal Article
Activation of renal angiotensin type 1 receptor contributes to the pathogenesis of progressive renal injury in a rat model of chronic cardiorenal syndrome
Homma, Tsuyoshi, Sonoda, Hiroko, Manabe, Kenichi, Arai, Kiyoshi, Mizuno, Makoto, Sada, Toshio, Ikeda, Masahiro
Published in American journal of physiology. Renal physiology (15.03.2012)
Published in American journal of physiology. Renal physiology (15.03.2012)
Get full text
Journal Article
Activation of renal angiotensin type 1 receptor contributes to the pathogenesis of progressive renal injury in a rat model of chronic cardiorenal syndrome
HOMMA, Tsuyoshi, SONODA, Hiroko, MANABE, Kenichi, ARAI, Kiyoshi, MIZUNO, Makoto, SADA, Toshio, IKEDA, Masahiro
Published in American journal of physiology. Renal physiology (2012)
Get full text
Published in American journal of physiology. Renal physiology (2012)
Journal Article
신질환의 치료를 위한 의약
HISATOMI RIE, NAKAJIMA SHIN, HOMMA TSUYOSHI, SAWANOBORI TOMOKO, YOSHIMURA MOTONOBU, ARAI KIYOSHI
Year of Publication 14.11.2018
Get full text
Year of Publication 14.11.2018
Patent
MEDICINE FOR TREATING RENAL DISEASE
HOMMA, Tsuyoshi, YOSHIMURA, Motonobu, SAWANOBORI, Tomoko, ARAI, Kiyoshi, NAKAJIMA, Shin, HISATOMI, Rie
Year of Publication 28.09.2017
Get full text
Year of Publication 28.09.2017
Patent
Histone demethylase LSD1 and biological sex: impact on blood pressure and aldosterone production
Huang, Yuefei, Ting, Pei Yee, Yao, Tham M, Homma, Tsuyoshi, Brooks, Danielle, Katayama Rangel, Isis A, Adler, Gail K, Romero, Jose R, Williams, Jonathan S, Pojoga, Luminita H, Williams, Gordon H
Published in Journal of endocrinology (01.11.2018)
Get full text
Published in Journal of endocrinology (01.11.2018)
Journal Article