Targeting of PYK2 Synergizes with EGFR Antagonists in Basal-like TNBC and Circumvents HER3-Associated Resistance via the NEDD4-NDRG1 Axis
Verma, Nandini, Müller, Anna-Katharina, Kothari, Charu, Panayotopoulou, Effrosini, Kedan, Amir, Selitrennik, Michael, Mills, Gordon B, Nguyen, Lan K, Shin, Sungyoung, Karn, Thomas, Holtrich, Uwe, Lev, Sima
Published in Cancer research (Chicago, Ill.) (01.01.2017)
Published in Cancer research (Chicago, Ill.) (01.01.2017)
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Journal Article
Association Between Genomic Metrics and Immune Infiltration in Triple-Negative Breast Cancer
Karn, Thomas, Jiang, Tingting, Hatzis, Christos, Sänger, Nicole, El-Balat, Ahmed, Rody, Achim, Holtrich, Uwe, Becker, Sven, Bianchini, Giampaolo, Pusztai, Lajos
Published in JAMA oncology (01.12.2017)
Published in JAMA oncology (01.12.2017)
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Journal Article
Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer
Ruckhäberle, Eugen, Rody, Achim, Engels, Knut, Gaetje, Regine, von Minckwitz, Gunter, Schiffmann, Susanne, Grösch, Sabine, Geisslinger, Gerd, Holtrich, Uwe, Karn, Thomas, Kaufmann, Manfred
Published in Breast cancer research and treatment (01.11.2008)
Published in Breast cancer research and treatment (01.11.2008)
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Journal Article
Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures
Karn, Thomas, Pusztai, Lajos, Holtrich, Uwe, Iwamoto, Takayuki, Shiang, Christine Y, Schmidt, Marcus, Müller, Volkmar, Solbach, Christine, Gaetje, Regine, Hanker, Lars, Ahr, Andre, Liedtke, Cornelia, Ruckhäberle, Eugen, Kaufmann, Manfred, Rody, Achim
Published in PloS one (29.12.2011)
Published in PloS one (29.12.2011)
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Journal Article
Histotype-specific analysis of acid ceramidase expression in ovarian cancer
El-Balat, Ahmed, Karn, Thomas, Holtrich, Uwe, Becker, Sven, Kommoss, Stefan, Győrffy, Balázs, Anglesio, Michael S., Huntsman, David G., Drosos, Zacharias, Rody, Achim, Gevensleben, Heidrun, Hanker, Lars C.
Published in Virchows Archiv : an international journal of pathology (01.06.2020)
Published in Virchows Archiv : an international journal of pathology (01.06.2020)
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Journal Article
Molecular differences between younger versus older ER-positive and HER2-negative breast cancers
Qing, Tao, Karn, Thomas, Rozenblit, Mariya, Foldi, Julia, Marczyk, Michal, Shan, Naing Lin, Blenman, Kim, Holtrich, Uwe, Kalinsky, Kevin, Meric-Bernstam, Funda, Pusztai, Lajos
Published in NPJ breast cancer (07.11.2022)
Published in NPJ breast cancer (07.11.2022)
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Journal Article
Proliferation and estrogen signaling can distinguish patients at risk for early versus late relapse among estrogen receptor positive breast cancers
Bianchini, Giampaolo, Pusztai, Lajos, Karn, Thomas, Iwamoto, Takayuki, Rody, Achim, Kelly, Catherine, Müller, Volkmar, Schmidt, Schmidt, Qi, Yuan, Holtrich, Uwe, Becker, Sven, Santarpia, Libero, Fasolo, Angelica, Del Conte, Gianluca, Zambetti, Milvia, Sotiriou, Christos, Haibe-Kains, Benjamin, Symmans, W Fraser, Gianni, Luca
Published in Breast cancer research : BCR (23.09.2013)
Published in Breast cancer research : BCR (23.09.2013)
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Journal Article
Melanoma antigen family A identified by the bimodality index defines a subset of triple negative breast cancers as candidates for immune response augmentation
Karn, Thomas, Pusztai, Lajos, Ruckhäberle, Eugen, Liedtke, Cornelia, Müller, Volkmar, Schmidt, Marcus, Metzler, Dirk, Wang, Jing, Coombes, Kevin R, Gätje, Regine, Hanker, Lars, Solbach, Christine, Ahr, Andre, Holtrich, Uwe, Rody, Achim, Kaufmann, Manfred
Published in European journal of cancer (1990) (01.01.2012)
Published in European journal of cancer (1990) (01.01.2012)
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Journal Article
Poor Outcome in Estrogen Receptor–Positive Breast Cancers Predicted by Loss of Plexin B1
RODY, Achim, HOLTRICH, Uwe, AHR, Andre, SOLBACH, Christine, KARN, Thomas, KAUFMANN, Manfred, GAETJE, Regine, GEHRMANN, Mathias, ENGELS, Knut, VON MINCKWITZ, Gunter, LOIBL, Sibylle, DIALLO-DANEBROCK, Raihanatou, RUCKHÄBERLE, Eugen, METZLER, Dirk
Published in Clinical cancer research (15.02.2007)
Published in Clinical cancer research (15.02.2007)
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Journal Article
Identification of high risk breast-cancer patients by gene expression profiling
Ahr, André, Karn, Thomas, Solbach, Christine, Seiter, Tanja, Strebhardt, Klaus, Holtrich, Uwe, Kaufmann, Manfred
Published in The Lancet (British edition) (12.01.2002)
Published in The Lancet (British edition) (12.01.2002)
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Journal Article
Prognostic significance of polo-like kinase (PLK) expression in non-small cell lung cancer
WOLF, G, ELEZ, R, DOERMER, A, HOLTRICH, U, ACKERMANN, H, STUTTE, H. J, ALTMANNSBERGER, H.-M, RÜBSAMEN-WAIGMANN, H, STREBHARDT, K
Published in Oncogene (06.02.1997)
Published in Oncogene (06.02.1997)
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Journal Article
Endometriosis may be generated by mimicking the ontogenetic development of the female genital tract
Gaetje, Regine, M.D, Holtrich, Uwe, Ph.D, Engels, Knut, M.D, Kissler, Stefan, M.D, Rody, Achim, M.D, Karn, Thomas, Ph.D, Kaufmann, Manfred, M.D
Published in Fertility and sterility (01.03.2007)
Published in Fertility and sterility (01.03.2007)
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Journal Article
Control of dataset bias in combined Affymetrix cohorts of triple negative breast cancer
Karn, Thomas, Rody, Achim, Müller, Volkmar, Schmidt, Marcus, Becker, Sven, Holtrich, Uwe, Pusztai, Lajos
Published in Genomics data (01.12.2014)
Published in Genomics data (01.12.2014)
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Journal Article
PDZ-Domain-Mediated Interaction of the Eph-Related Receptor Tyrosine Kinase EphB3 and the Ras-Binding Protein AF6 Depends on the Kinase Activity of the Receptor
Hock, Bjorn, Bohme, Beatrix, Karn, Thomas, Yamamoto, Takaharu, Kaibuchi, Kozo, Holtrich, Uwe, Holland, Sacha, Pawson, Tony, Rubsamen-Waigmann, Helga, Strebhardt, Klaus
Published in Proceedings of the National Academy of Sciences - PNAS (18.08.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (18.08.1998)
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Journal Article
Molecular classification of breast cancer patients by gene expression profiling
Ahr, André, Holtrich, Uwe, Solbach, Christine, Scharl, Anton, Strebhardt, Klaus, Karn, Thomas, Kaufmann, Manfred
Published in The Journal of pathology (01.10.2001)
Published in The Journal of pathology (01.10.2001)
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Journal Article
FSCN1 as prognostic marker in borderline tumors of the ovary
El-Balat, Ahmed, Holtrich, Uwe, Karn, Thomas, Becker, Sven
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
Adhesion induced expression of the serine/threonine kinase Fnk in human macrophages
HOLTRICH, Uwe, WOLF, Georg, KUHL, Dietmar, STREBHARDT, Klaus, JUPING YUAN, BEREITER-HAHN, Jürgen, KARN, Thomas, WEILER, Markus, KAUSELMANN, Gunther, REHLI, Michael, ANDREESEN, Reinhard, KAUFMANN, Manfred
Published in Oncogene (05.10.2000)
Published in Oncogene (05.10.2000)
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Journal Article
T-cell metagene predicts a favorable prognosis in estrogen receptor-negative and HER2-positive breast cancers
Rody, Achim, Holtrich, Uwe, Pusztai, Laos, Liedtke, Cornelia, Gaetje, Regine, Ruckhaeberle, Eugen, Solbach, Christine, Hanker, Lars, Ahr, Andre, Metzler, Dirk, Engels, Knut, Karn, Thomas, Kaufmann, Manfred
Published in Breast cancer research : BCR (01.01.2009)
Published in Breast cancer research : BCR (01.01.2009)
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