Single-cell analysis of germinal-center B cells informs on lymphoma cell of origin and outcome
Holmes, Antony B, Corinaldesi, Clarissa, Shen, Qiong, Kumar, Rahul, Compagno, Nicolo, Wang, Zhong, Nitzan, Mor, Grunstein, Eli, Pasqualucci, Laura, Dalla-Favera, Riccardo, Basso, Katia
Published in The Journal of experimental medicine (05.10.2020)
Published in The Journal of experimental medicine (05.10.2020)
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Journal Article
Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis
Zhang, Jiyuan, Dominguez-Sola, David, Hussein, Shafinaz, Lee, Ji-Eun, Holmes, Antony B, Bansal, Mukesh, Vlasevska, Sofija, Mo, Tongwei, Tang, Hongyan, Basso, Katia, Ge, Kai, Dalla-Favera, Riccardo, Pasqualucci, Laura
Published in Nature medicine (01.10.2015)
Published in Nature medicine (01.10.2015)
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Journal Article
Genetics of Follicular Lymphoma Transformation
Pasqualucci, Laura, Khiabanian, Hossein, Fangazio, Marco, Vasishtha, Mansi, Messina, Monica, Holmes, Antony B., Ouillette, Peter, Trifonov, Vladimir, Rossi, Davide, Tabbò, Fabrizio, Ponzoni, Maurilio, Chadburn, Amy, Murty, Vundavalli V., Bhagat, Govind, Gaidano, Gianluca, Inghirami, Giorgio, Malek, Sami N., Rabadan, Raul, Dalla-Favera, Riccardo
Published in Cell reports (Cambridge) (01.01.2014)
Published in Cell reports (Cambridge) (01.01.2014)
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Journal Article
Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome
Fabbri, Giulia, Khiabanian, Hossein, Holmes, Antony B, Wang, Jiguang, Messina, Monica, Mullighan, Charles G, Pasqualucci, Laura, Rabadan, Raul, Dalla-Favera, Riccardo
Published in The Journal of experimental medicine (21.10.2013)
Published in The Journal of experimental medicine (21.10.2013)
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Journal Article
Identification of human germinal center light and dark zone cells and their relationship to human B-cell lymphomas
Victora, Gabriel D., Dominguez-Sola, David, Holmes, Antony B., Deroubaix, Stephanie, Dalla-Favera, Riccardo, Nussenzweig, Michel C.
Published in Blood (13.09.2012)
Published in Blood (13.09.2012)
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Journal Article
tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma
Maute, Roy L., Schneider, Christof, Sumazin, Pavel, Holmes, Antony, Califano, Andrea, Basso, Katia, Dalla-Favera, Riccardo
Published in Proceedings of the National Academy of Sciences - PNAS (22.01.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (22.01.2013)
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Journal Article
Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma
Meyer, Stefanie N., Scuoppo, Claudio, Vlasevska, Sofija, Bal, Elodie, Holmes, Antony B., Holloman, Mara, Garcia-Ibanez, Laura, Nataraj, Sarah, Duval, Romain, Vantrimpont, Thomas, Basso, Katia, Brooks, Nigel, Dalla-Favera, Riccardo, Pasqualucci, Laura
Published in Immunity (Cambridge, Mass.) (17.09.2019)
Published in Immunity (Cambridge, Mass.) (17.09.2019)
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Journal Article
Combined Genetic Inactivation of β2-Microglobulin and CD58 Reveals Frequent Escape from Immune Recognition in Diffuse Large B Cell Lymphoma
Challa-Malladi, Madhavi, Lieu, Yen K., Califano, Olivia, Holmes, Antony B., Bhagat, Govind, Murty, Vundavalli V., Dominguez-Sola, David, Pasqualucci, Laura, Dalla-Favera, Riccardo
Published in Cancer cell (13.12.2011)
Published in Cancer cell (13.12.2011)
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Journal Article
MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis
Brescia, Paola, Schneider, Christof, Holmes, Antony B., Shen, Qiong, Hussein, Shafinaz, Pasqualucci, Laura, Basso, Katia, Dalla-Favera, Riccardo
Published in Cancer cell (10.09.2018)
Published in Cancer cell (10.09.2018)
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Journal Article
The CREBBP Acetyltransferase Is a Haploinsufficient Tumor Suppressor in B-cell Lymphoma
Zhang, Jiyuan, Vlasevska, Sofija, Wells, Victoria A, Nataraj, Sarah, Holmes, Antony B, Duval, Romain, Meyer, Stefanie N, Mo, Tongwei, Basso, Katia, Brindle, Paul K, Hussein, Shafinaz, Dalla-Favera, Riccardo, Pasqualucci, Laura
Published in Cancer discovery (01.03.2017)
Published in Cancer discovery (01.03.2017)
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Journal Article
Common nonmutational NOTCH1 activation in chronic lymphocytic leukemia
Fabbri, Giulia, Holmes, Antony B., Viganotti, Mara, Scuoppo, Claudio, Belver, Laura, Herranz, Daniel, Yan, Xiao-Jie, Kieso, Yasmine, Rossi, Davide, Gaidano, Gianluca, Chiorazzi, Nicholas, Ferrando, Adolfo A., Dalla-Favera, Riccardo
Published in Proceedings of the National Academy of Sciences - PNAS (04.04.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (04.04.2017)
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Journal Article
Combined Genetic Inactivation of beta 2-Microglobulin and CD58 Reveals Frequent Escape from Immune Recognition in Diffuse Large B Cell Lymphoma
Challa-Malladi, Madhavi, Lieu, Yen K, Califano, Olivia, Holmes, Antony B, Bhagat, Govind, Murty, Vundavalli V, Dominguez-Sola, David, Pasqualucci, Laura, Dalla-Favera, Riccardo
Published in Cancer cell (13.12.2011)
Published in Cancer cell (13.12.2011)
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Journal Article
Super-enhancer hypermutation alters oncogene expression in B cell lymphoma
Bal, Elodie, Kumar, Rahul, Hadigol, Mohammad, Holmes, Antony B., Hilton, Laura K., Loh, Jui Wan, Dreval, Kostiantyn, Wong, Jasper C. H., Vlasevska, Sofija, Corinaldesi, Clarissa, Soni, Rajesh Kumar, Basso, Katia, Morin, Ryan D., Khiabanian, Hossein, Pasqualucci, Laura, Dalla-Favera, Riccardo
Published in Nature (London) (28.07.2022)
Published in Nature (London) (28.07.2022)
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Journal Article
KMT2D acetylation by CREBBP reveals a cooperative functional interaction at enhancers in normal and malignant germinal center B cells
Vlasevska, Sofija, Garcia-Ibanez, Laura, Duval, Romain, Holmes, Antony B, Jahan, Rahat, Cai, Bowen, Kim, Andrew, Mo, Tongwei, Basso, Katia, Soni, Rajesh K, Bhagat, Govind, Dalla-Favera, Riccardo, Pasqualucci, Laura
Published in Proceedings of the National Academy of Sciences - PNAS (14.03.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (14.03.2023)
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Journal Article
The genetics of nodal marginal zone lymphoma
Spina, Valeria, Khiabanian, Hossein, Messina, Monica, Monti, Sara, Cascione, Luciano, Bruscaggin, Alessio, Spaccarotella, Elisa, Holmes, Antony B., Arcaini, Luca, Lucioni, Marco, Tabbò, Fabrizio, Zairis, Sakellarios, Diop, Fary, Cerri, Michaela, Chiaretti, Sabina, Marasca, Roberto, Ponzoni, Maurilio, Deaglio, Silvia, Ramponi, Antonio, Tiacci, Enrico, Pasqualucci, Laura, Paulli, Marco, Falini, Brunangelo, Inghirami, Giorgio, Bertoni, Francesco, Foà, Robin, Rabadan, Raul, Gaidano, Gianluca, Rossi, Davide
Published in Blood (08.09.2016)
Published in Blood (08.09.2016)
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Journal Article
BCL6 positively regulates AID and germinal center gene expression via repression of miR-155
Basso, Katia, Schneider, Christof, Shen, Qiong, Holmes, Antony B, Setty, Manu, Leslie, Christina, Dalla-Favera, Riccardo
Published in The Journal of experimental medicine (17.12.2012)
Published in The Journal of experimental medicine (17.12.2012)
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Journal Article
MEF2B C-terminal mutations enhance transcriptional activity and stability to drive B cell lymphomagenesis
Yu, Chuanjiang, Shen, Qiong, Holmes, Antony B., Mo, Tongwei, Tosato, Anna, Soni, Rajesh Kumar, Corinaldesi, Clarissa, Koul, Sanjay, Pasqualucci, Laura, Hussein, Shafinaz, Forouhar, Farhad, Dalla-Favera, Riccardo, Basso, Katia
Published in Nature communications (21.08.2024)
Published in Nature communications (21.08.2024)
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Journal Article
microRNA 28 controls cell proliferation and is down-regulated in B-cell lymphomas
Schneider, Christof, Setty, Manu, Holmes, Antony B., Maute, Roy L., Leslie, Christina S., Mussolin, Lara, Rosolen, Angelo, Dalla-Favera, Riccardo, Basso, Katia
Published in Proceedings of the National Academy of Sciences - PNAS (03.06.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (03.06.2014)
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Journal Article