Search Results - "HOLLA,WOLFGANG" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

The synthesis of selected phase II metabolites – Ο-glucuronides and sulfates of drug development candidates

The synthesis of selected phase II metabolites – Ο-glucuronides and sulfates of drug development candidates

by Atzrodt, Jens, Derdau, Volker, Holla, Wolfgang, Sandvoss, Martin
Published in ARKIVOC (29.01.2012)

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Journal Article Web Resource

Ruthenium-Catalyzed Selective α,β-Deuteration of Bioactive Amines

Ruthenium-Catalyzed Selective α,β-Deuteration of Bioactive Amines

by Neubert, Lorenz, Michalik, Dirk, Bähn, Sebastian, Imm, Sebastian, Neumann, Helfried, Atzrodt, Jens, Derdau, Volker, Holla, Wolfgang, Beller, Matthias
Published in Journal of the American Chemical Society (25.07.2012)

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Journal Article

One-pot synthesis of human metabolites of SAR548304 by fungal peroxygenases

One-pot synthesis of human metabolites of SAR548304 by fungal peroxygenases

by Kiebist, Jan, Holla, Wolfgang, Heidrich, Johannes, Poraj-Kobielska, Marzena, Sandvoss, Martin, Simonis, Reiner, Gröbe, Glenn, Atzrodt, Jens, Hofrichter, Martin, Scheibner, Katrin
Published in Bioorganic & medicinal chemistry (01.08.2015)

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Journal Article

Mechanistic investigations of the liver toxicity of the free fatty acid receptor 1 agonist fasiglifam (TAK875) and its primary metabolites

Mechanistic investigations of the liver toxicity of the free fatty acid receptor 1 agonist fasiglifam (TAK875) and its primary metabolites

by Ackerson, Timothy, Amberg, Alexander, Atzrodt, Jens, Arabeyre, Catherine, Defossa, Elisabeth, Dorau, Martina, Dudda, Angela, Dwyer, Jacquelyn, Holla, Wolfgang, Kissner, Thomas, Kohlmann, Markus, Kürzel, Ulrich, Pánczél, József, Rajanna, Shibani, Riedel, Jens, Schmidt, Friedemann, Wäse, Kerstin, Weitz, Dietmar, Derdau, Volker
Published in Journal of biochemical and molecular toxicology (01.08.2019)

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Journal Article

Dynamic Kinetic Resolution of α-Amino Acid Esters in the Presence of Aldehydes

Dynamic Kinetic Resolution of α-Amino Acid Esters in the Presence of Aldehydes

by Schichl, Daniel A., Enthaler, Stephan, Holla, Wolfgang, Riermeier, Thomas, Kragl, Udo, Beller, Matthias
Published in European Journal of Organic Chemistry (01.07.2008)

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Book Review Journal Article

H/D-exchange reactions with hydride-activated catalysts

H/D-exchange reactions with hydride-activated catalysts

by Derdau, Volker, Atzrodt, Jens, Holla, Wolfgang
Published in Journal of labelled compounds & radiopharmaceuticals (01.04.2007)

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Journal Article Conference Proceeding

Preparation of labeled human drug metabolites and drug-drug interaction-probes with fungal peroxygenases

Preparation of labeled human drug metabolites and drug-drug interaction-probes with fungal peroxygenases

by Poraj-Kobielska, Marzena, Atzrodt, Jens, Holla, Wolfgang, Sandvoss, Martin, Gröbe, Glenn, Scheibner, Katrin, Hofrichter, Martin
Published in Journal of labelled compounds & radiopharmaceuticals (01.07.2013)

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Journal Article

ENZYMATIC-SYNTHESIS OF SELECTIVELY PROTECTED GLYCALS

ENZYMATIC-SYNTHESIS OF SELECTIVELY PROTECTED GLYCALS

by HOLLA, EW
Published in Angewandte Chemie International Edition (01.02.1989)

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Journal Article

PROCESS FOR THE PREPARATION OF DEUTERATED COMPOUNDS CONTAINING N-ALKYL GROUPS

PROCESS FOR THE PREPARATION OF DEUTERATED COMPOUNDS CONTAINING N-ALKYL GROUPS

by MICHALIK DIRK, HOLLA WOLFGANG, DERDAU VOLKER, NEUBERT LORENZ, ATZRODT JENS, BELLER MATTHIAS
Year of Publication 11.03.2014

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Patent

processo para separação enanciomérica enzimática de 3(r)-hidróxi-1-metil-4-(2,4,6-trimetoxifenil)-1,2,3,6-tetrahidro-piridina e 3-(s)- hidróxi-1-metil-4-(2,4,6-trimetoxifenil)-1,2,3,6-tetrahidro-piridina e os ésteres de ácido carboxílico

processo para separação enanciomérica enzimática de 3(r)-hidróxi-1-metil-4-(2,4,6-trimetoxifenil)-1,2,3,6-tetrahidro-piridina e 3-(s)- hidróxi-1-metil-4-(2,4,6-trimetoxifenil)-1,2,3,6-tetrahidro-piridina e os ésteres de ácido carboxílico

by Wolfgang Holla
Year of Publication 25.05.2021

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Patent

processo para separação enanciomérica enzimática de 3(r)-hidróxi-1-metil-4-(2,4,6-trimetoxifenil)-1,2,3,6-tetrahidro-piridina e 3-(s)- hidróxi-1-metil-4-(2,4,6-trimetoxifenil)-1,2,3,6-tetrahidro-piridina e os ésteres de ácido carboxílico

processo para separação enanciomérica enzimática de 3(r)-hidróxi-1-metil-4-(2,4,6-trimetoxifenil)-1,2,3,6-tetrahidro-piridina e 3-(s)- hidróxi-1-metil-4-(2,4,6-trimetoxifenil)-1,2,3,6-tetrahidro-piridina e os ésteres de ácido carboxílico

by Wolfgang Holla
Year of Publication 18.09.2018

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Patent

METHOD FOR ENZMATIC ENANTIOMER-SEPARATION OF 3(R)- AND 3(S)-HYDROXY-1-METHYL-4(2,4,6-TRIMETHOXYPHENYL)-1,2,3,6-TETRAHYDRO-PYRIDINE OR ITS CARBOXYLIC ACID ESTERS

METHOD FOR ENZMATIC ENANTIOMER-SEPARATION OF 3(R)- AND 3(S)-HYDROXY-1-METHYL-4(2,4,6-TRIMETHOXYPHENYL)-1,2,3,6-TETRAHYDRO-PYRIDINE OR ITS CARBOXYLIC ACID ESTERS

by HOLLA, WOLFGANG
Year of Publication 28.08.2012

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Patent

PROCESS FOR THE ENZYMATIC SEPARATION OF ENANTIOMERS OF 3(R)- AND 3(S)-HYDROXY-1-METHYL-4-(2,4,6-TRIMETHOXYPHENYL)-1,2,3,6-TETRAHYDROPYRIDINE OR ITS CARBOXYLIC ACID ESTERS

PROCESS FOR THE ENZYMATIC SEPARATION OF ENANTIOMERS OF 3(R)- AND 3(S)-HYDROXY-1-METHYL-4-(2,4,6-TRIMETHOXYPHENYL)-1,2,3,6-TETRAHYDROPYRIDINE OR ITS CARBOXYLIC ACID ESTERS

by HOLLA, WOLFGANG
Year of Publication 05.04.2011

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Patent

Fremgangsmåde til enzymatisk enantiomer-separation af 3(r)- og 3(s)-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-1,2,3,6-tetrahydro-pyridin respektive carboxylsyreester

Fremgangsmåde til enzymatisk enantiomer-separation af 3(r)- og 3(s)-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-1,2,3,6-tetrahydro-pyridin respektive carboxylsyreester

by HOLLA, WOLFGANG
Year of Publication 08.11.2010

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Patent

METHOD FOR ENZYMATIC ENANTIOMER-SEPARATION OF 3(R)- AND 3(S)-HYDROXY-1- METHYL-4-(2,4, 6-TRIMETHOXYPHENYL)-1, 2,3,6- TETRAHYDRO-PYRIDINE OR ITS CARBOXYLIC ACID ESTERS

METHOD FOR ENZYMATIC ENANTIOMER-SEPARATION OF 3(R)- AND 3(S)-HYDROXY-1- METHYL-4-(2,4, 6-TRIMETHOXYPHENYL)-1, 2,3,6- TETRAHYDRO-PYRIDINE OR ITS CARBOXYLIC ACID ESTERS

by WOLFGANG HOLLA
Year of Publication 29.09.2010

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Patent

VERFAHREN ZUR ENZYMATISCHEN ENANTIOMEREN-TRENNUNG VON 3(R)- UND 3(S)-HYDROXY-1- METHYL-4-(2,4, 6- TRIMETHOXYPHENYL)-1, 2,3,6- TETRAHYDRO-PYRIDIN BZW. DER CARBONSÄUREESTER

VERFAHREN ZUR ENZYMATISCHEN ENANTIOMEREN-TRENNUNG VON 3(R)- UND 3(S)-HYDROXY-1- METHYL-4-(2,4, 6- TRIMETHOXYPHENYL)-1, 2,3,6- TETRAHYDRO-PYRIDIN BZW. DER CARBONSÄUREESTER

by HOLLA, WOLFGANG
Year of Publication 15.07.2010

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Patent

METHOD FOR ENZYMATIC ENANTIOMER-SEPARATION OF 3(R)- AND 3(S)-HYDROXY-1- METHYL-4-(2,4, 6-TRIMETHOXYPHENYL)-1, 2,3,6- TETRAHYDRO-PYRIDINE OR ITS CARBOXYLIC ACID ESTERS

METHOD FOR ENZYMATIC ENANTIOMER-SEPARATION OF 3(R)- AND 3(S)-HYDROXY-1- METHYL-4-(2,4, 6-TRIMETHOXYPHENYL)-1, 2,3,6- TETRAHYDRO-PYRIDINE OR ITS CARBOXYLIC ACID ESTERS

by HOLLA, WOLFGANG
Year of Publication 14.07.2010

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Patent

VERFAHREN ZUR HERSTELLUNG DER ENANTIOMEREN FORMEN VON 2- SUBSTITUIERTEN 2-(2,5-DIOXOIMIDAZOLIDIN-1-YL)ESSIGSÄUREDERIVATEN

VERFAHREN ZUR HERSTELLUNG DER ENANTIOMEREN FORMEN VON 2- SUBSTITUIERTEN 2-(2,5-DIOXOIMIDAZOLIDIN-1-YL)ESSIGSÄUREDERIVATEN

by HOLLA, WOLFGANG
Year of Publication 15.01.2009

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Patent

ΜΕΘΟΔΟΣ ΓΙΑ ΤΟΝ ΕΝΖΥΜΑΤΙΚΟ ΔΙΑΧΩΡΙΣΜΟ ΕΝΑΝΤΙΟΜΕΡΩΝ ΤΗΣ 3(R)- KAI 3(S)-ΥΔΡΟΞΥ-1-ΜΕΘΥΛΟ-4-(2,4,6-ΤΡΙΜΕΘΟΞΥΦΑΙΝΥΛΟ)-1,2,3,6-ΤΕΤΡΑΫΔΡΟ-ΠΥΡΙΔΙΝΗΣ Ή ΤΩΝ ΕΣΤΕΡΩΝ ΚΑΡΒΟΞΥΛΙΚΟΥ ΟΞΕΟΣ ΑΥΤΗΣ

ΜΕΘΟΔΟΣ ΓΙΑ ΤΟΝ ΕΝΖΥΜΑΤΙΚΟ ΔΙΑΧΩΡΙΣΜΟ ΕΝΑΝΤΙΟΜΕΡΩΝ ΤΗΣ 3(R)- KAI 3(S)-ΥΔΡΟΞΥ-1-ΜΕΘΥΛΟ-4-(2,4,6-ΤΡΙΜΕΘΟΞΥΦΑΙΝΥΛΟ)-1,2,3,6-ΤΕΤΡΑΫΔΡΟ-ΠΥΡΙΔΙΝΗΣ Ή ΤΩΝ ΕΣΤΕΡΩΝ ΚΑΡΒΟΞΥΛΙΚΟΥ ΟΞΕΟΣ ΑΥΤΗΣ

by HOLLA WOLFGANG
Year of Publication 10.06.2015

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Patent

VERFAHREN ZUR HERSTELLUNG DER ENANTIOMEREN FORMEN VON 2- SUBSTITUIERTEN 2-(2,5-DIOXOIMIDAZOLIDIN-1- YL)ESSIGSÄUREDERIVATEN

VERFAHREN ZUR HERSTELLUNG DER ENANTIOMEREN FORMEN VON 2- SUBSTITUIERTEN 2-(2,5-DIOXOIMIDAZOLIDIN-1- YL)ESSIGSÄUREDERIVATEN

by HOLLA, WOLFGANG
Year of Publication 15.02.2008

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Patent

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