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Published in Circulation research (09.10.2015)
Published in Circulation research (09.10.2015)
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The effect of host genetics on the gut microbiome
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Published in Nature genetics (01.11.2016)
Published in Nature genetics (01.11.2016)
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Human disease-associated genetic variation impacts large intergenic non-coding RNA expression
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Published in PLoS genetics (01.01.2013)
Published in PLoS genetics (01.01.2013)
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Nonalcoholic fatty liver disease: A main driver of insulin resistance or a dangerous liaison?
Gruben, Nanda, Shiri-Sverdlov, Ronit, Koonen, Debby P.Y., Hofker, Marten H.
Published in Biochimica et biophysica acta (01.11.2014)
Published in Biochimica et biophysica acta (01.11.2014)
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Adipose tissue macrophages induce hepatic neutrophil recruitment and macrophage accumulation in mice
Bijnen, Mitchell, Josefs, Tatjana, Cuijpers, Ilona, Maalsen, Constantijn J, van de Gaar, José, Vroomen, Maria, Wijnands, Erwin, Rensen, Sander S, Greve, Jan Willem M, Hofker, Marten H, Biessen, Erik A L, Stehouwer, Coen D A, Schalkwijk, Casper G, Wouters, Kristiaan
Published in Gut (01.07.2018)
Published in Gut (01.07.2018)
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CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL
Bartuzi, Paulina, Billadeau, Daniel D., Favier, Robert, Rong, Shunxing, Dekker, Daphne, Fedoseienko, Alina, Fieten, Hille, Wijers, Melinde, Levels, Johannes H., Huijkman, Nicolette, Kloosterhuis, Niels, van der Molen, Henk, Brufau, Gemma, Groen, Albert K., Elliott, Alison M., Kuivenhoven, Jan Albert, Plecko, Barbara, Grangl, Gernot, McGaughran, Julie, Horton, Jay D., Burstein, Ezra, Hofker, Marten H., van de Sluis, Bart
Published in Nature communications (11.03.2016)
Published in Nature communications (11.03.2016)
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The genome revolution and its role in understanding complex diseases
Hofker, Marten H., Fu, Jingyuan, Wijmenga, Cisca
Published in Biochimica et biophysica acta (01.10.2014)
Published in Biochimica et biophysica acta (01.10.2014)
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Book Review
COMMD Family Regulates Plasma LDL Levels and Attenuates Atherosclerosis Through Stabilizing the CCC Complex in Endosomal LDLR Trafficking
Fedoseienko, Alina, Wijers, Melinde, Wolters, Justina C, Dekker, Daphne, Smit, Marieke, Huijkman, Nicolette, Kloosterhuis, Niels, Klug, Helene, Schepers, Aloys, van Dijk, Ko Willems, Levels, Johannes H M, Billadeau, Daniel D, Hofker, Marten H, van Deursen, Jan, Westerterp, Marit, Burstein, Ezra, Kuivenhoven, Jan Albert, van de Sluis, Bart
Published in Circulation research (08.06.2018)
Published in Circulation research (08.06.2018)
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Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis
Wouters, Kristiaan, van Gorp, Patrick J., Bieghs, Veerle, Gijbels, Marion J., Duimel, Hans, Lütjohann, Dieter, Kerksiek, Anja, van Kruchten, Roger, Maeda, Nobuyo, Staels, Bart, van Bilsen, Marc, Shiri‐Sverdlov, Ronit, Hofker, Marten H.
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Published in Hepatology (Baltimore, Md.) (01.08.2008)
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Published in PloS one (28.03.2012)
Published in PloS one (28.03.2012)
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NASH and atherosclerosis are two aspects of a shared disease: Central role for macrophages
Bieghs, Veerle, Rensen, Patrick C.N, Hofker, Marten H, Shiri-Sverdlov, Ronit
Published in Atherosclerosis (01.02.2012)
Published in Atherosclerosis (01.02.2012)
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LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease
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Published in PloS one (25.01.2012)
Published in PloS one (25.01.2012)
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Genetic and epigenetic regulation of gene expression in fetal and adult human livers
Bonder, Marc Jan, Kasela, Silva, Kals, Mart, Tamm, Riin, Lokk, Kaie, Barragan, Isabel, Buurman, Wim A, Deelen, Patrick, Greve, Jan-Willem, Ivanov, Maxim, Rensen, Sander S, van Vliet-Ostaptchouk, Jana V, Wolfs, Marcel G, Fu, Jingyuan, Hofker, Marten H, Wijmenga, Cisca, Zhernakova, Alexandra, Ingelman-Sundberg, Magnus, Franke, Lude, Milani, Lili
Published in BMC genomics (04.10.2014)
Published in BMC genomics (04.10.2014)
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Pleiotropic Effects of Lipid Genes on Plasma Glucose, HbA1c, and HOMA-IR Levels
NAISHI LI, VAN DER SIJDE, Marijke R, JINGYUAN FU, BAKKER, Stephan J. L, DULLAART, Robin P. F, VAN DER HARST, Pim, GANSEVOORT, Ron T, ELBERS, Clara C, WIJMENGA, Cisca, SNIEDER, Harold, HOFKER, Marten H
Published in Diabetes (New York, N.Y.) (01.09.2014)
Published in Diabetes (New York, N.Y.) (01.09.2014)
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Plasma cholesteryl ester transfer protein is predominantly derived from Kupffer cells
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Published in Hepatology (Baltimore, Md.) (01.12.2015)
Published in Hepatology (Baltimore, Md.) (01.12.2015)
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Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice
Bieghs, Veerle, Wouters, Kristiaan, van Gorp, Patrick J, Gijbels, Marion J J, de Winther, Menno P J, Binder, Christoph J, Lütjohann, Dieter, Febbraio, Maria, Moore, Kathryn J, van Bilsen, Marc, Hofker, Marten H, Shiri-Sverdlov, Ronit
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2010)
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2010)
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Specific immunization strategies against oxidized low-density lipoprotein: A novel way to reduce nonalcoholic steatohepatitis in mice
Bieghs, Veerle, van Gorp, Patrick J., Walenbergh, Sofie M.A., Gijbels, Marion J., Verheyen, Fons, Buurman, Wim A., Briles, David E., Hofker, Marten H., Binder, Christoph J., Shiri-Sverdlov, Ronit
Published in Hepatology (Baltimore, Md.) (01.09.2012)
Published in Hepatology (Baltimore, Md.) (01.09.2012)
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Cathepsin D regulates lipid metabolism in murine steatohepatitis
Houben, Tom, Oligschlaeger, Yvonne, Hendrikx, Tim, Bitorina, Albert V., Walenbergh, Sofie M. A., van Gorp, Patrick J., Gijbels, Marion J. J., Friedrichs, Silvia, Plat, Jogchum, Schaap, Frank G., Lütjohann, Dieter, Hofker, Marten H., Shiri-Sverdlov, Ronit
Published in Scientific reports (14.06.2017)
Published in Scientific reports (14.06.2017)
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Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice
Wouters, Kristiaan, Bilsen, Marc van, Gorp, Patrick J. van, Bieghs, Veerle, Lütjohann, Dieter, Kerksiek, Anja, Staels, Bart, Hofker, Marten H., Shiri-Sverdlov, Ronit
Published in FEBS letters (05.03.2010)
Published in FEBS letters (05.03.2010)
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Bone marrow‐specific caspase‐1/11 deficiency inhibits atherosclerosis development in Ldlr−/− mice
Hendrikx, Tim, Jeurissen, Mike L. J, Gorp, Patrick J, Gijbels, Marion J, Walenbergh, Sofie M. A, Houben, Tom, Gorp, Rick, Pöttgens, Chantal C, Stienstra, Rinke, Netea, Mihai G, Hofker, Marten H, Donners, Marjo M. P. C, Shiri‐Sverdlov, Ronit
Published in The FEBS journal (01.06.2015)
Published in The FEBS journal (01.06.2015)
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