A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models
Zhou, Yiming, Castonguay, Philip, Sidhom, Eriene-Heidi, Clark, Abbe R., Dvela-Levitt, Moran, Kim, Sookyung, Sieber, Jonas, Wieder, Nicolas, Jung, Ji Yong, Andreeva, Svetlana, Reichardt, Jana, Dubois, Frank, Hoffmann, Sigrid C., Basgen, John M., Montesinos, Mónica S., Weins, Astrid, Johnson, Ashley C., Lander, Eric S., Garrett, Michael R., Hopkins, Corey R., Greka, Anna
Published in Science (American Association for the Advancement of Science) (08.12.2017)
Published in Science (American Association for the Advancement of Science) (08.12.2017)
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Journal Article
Kidney Injury Molecule-1 Is Specifically Expressed in Cystically-Transformed Proximal Tubules of the PKD/Mhm (cy/+) Rat Model of Polycystic Kidney Disease
Gauer, Stefan, Urbschat, Anja, Gretz, Norbert, Hoffmann, Sigrid C, Kränzlin, Bettina, Geiger, Helmut, Obermüller, Nicholas
Published in International journal of molecular sciences (01.06.2016)
Published in International journal of molecular sciences (01.06.2016)
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Journal Article
CTGF Is Expressed During Cystic Remodeling in the PKD/Mhm (cy/+) Rat Model for Autosomal-Dominant Polycystic Kidney Disease (ADPKD)
Gauer, Stefan, Holzmann, Yvonne, Kränzlin, Bettina, Hoffmann, Sigrid C., Gretz, Norbert, Hauser, Ingeborg A., Goppelt-Struebe, Margarete, Geiger, Helmut, Obermüller, Nicholas
Published in The journal of histochemistry and cytochemistry (01.12.2017)
Published in The journal of histochemistry and cytochemistry (01.12.2017)
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Journal Article
Transgenic Overexpression of Anks6 (p.R823W) Causes Polycystic Kidney Disease in Rats
Neudecker, Sabine, Walz, Rebecca, Menon, Kiran, Maier, Elena, Bihoreau, Marie-Therese, Obermüller, Nicholas, Kränzlin, Bettina, Gretz, Norbert, Hoffmann, Sigrid C
Published in The American journal of pathology (01.12.2010)
Published in The American journal of pathology (01.12.2010)
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Journal Article
Tracking mesenchymal stem cell contributions to regeneration in an immunocompetent cartilage regeneration model
Zwolanek, Daniela, Satué, María, Proell, Verena, Godoy, José R, Odörfer, Kathrin I, Flicker, Magdalena, Hoffmann, Sigrid C, Rülicke, Thomas, Erben, Reinhold G
Published in JCI insight (19.10.2017)
Published in JCI insight (19.10.2017)
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Journal Article
A new transgenic rat model overexpressing the angiotensin II type 2 receptor provides evidence for inhibition of cell proliferation in the outer adrenal cortex
Peters, Barbara, Podlich, Dirk, Ritter, Michael, Müller, Anja, Wanka, Heike, Maser-Gluth, Christiane, Seitz, Claudia, de Boni, Laura, Maier, Elena, Gretz, Norbert, Peters, Jörg, Hoffmann, Sigrid C
Published in American journal of physiology: endocrinology and metabolism (01.05.2012)
Published in American journal of physiology: endocrinology and metabolism (01.05.2012)
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Journal Article
Inhibition of Comt with tolcapone slows progression of polycystic kidney disease in the more severely affected PKD/Mhm (cy/+) substrain of the Hannover Sprague-Dawley rat
Boehn, Susanne N E, Spahn, Sonja, Neudecker, Sabine, Keppler, Andrea, Bihoreau, Marie-Thérèse, Kränzlin, Bettina, Pandey, Priyanka, Hoffmann, Sigrid C, Li, Li, Torres, Vicente E, Gröne, Hermann-Josef, Gretz, Norbert
Published in Nephrology, dialysis, transplantation (01.08.2013)
Published in Nephrology, dialysis, transplantation (01.08.2013)
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Journal Article
A new transgenic rat model overexpressing the angiotensin II type 2 receptor provides evidence for inhibition of cell proliferation in the outer adrenal cortex
PETERS, Barbara, PODLICH, Dirk, PETERS, Jorg, HOFFMANN, Sigrid C, RITTER, Michael, MÜLLER, Anja, WANKA, Heike, MASER-GLUTH, Christiane, SEITZ, Claudia, DE BONI, Laura, MAIER, Elena, GRETZ, Norbert
Published in American journal of physiology: endocrinology and metabolism (2012)
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Published in American journal of physiology: endocrinology and metabolism (2012)
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