Regorafenib enhances anti-PD1 immunotherapy efficacy in murine colorectal cancers and their combination prevents tumor regrowth
Doleschel, Dennis, Hoff, Sabine, Koletnik, Susanne, Rix, Anne, Zopf, Dieter, Kiessling, Fabian, Lederle, Wiltrud
Published in Journal of experimental & clinical cancer research (13.09.2021)
Published in Journal of experimental & clinical cancer research (13.09.2021)
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Journal Article
IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization
Yoon, Juhan, Leyva-Castillo, Juan Manuel, Wang, Guoxing, Galand, Claire, Oyoshi, Michiko K, Kumar, Lalit, Hoff, Sabine, He, Rui, Chervonsky, Alexander, Oppenheim, Joost J, Kuchroo, Vijay K, van den Brink, Marcel R M, Malefyt, Rene De Waal, Tessier, Philippe A, Fuhlbrigge, Robert, Rosenstiel, Philip, Terhorst, Cox, Murphy, George, Geha, Raif S
Published in The Journal of experimental medicine (19.09.2016)
Published in The Journal of experimental medicine (19.09.2016)
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Journal Article
Injury, dysbiosis, and filaggrin deficiency drive skin inflammation through keratinocyte IL-1α release
Archer, Nathan K., Jo, Jay-Hyun, Lee, Steven K., Kim, Dongwon, Smith, Barbara, Ortines, Roger V., Wang, Yu, Marchitto, Mark C., Ravipati, Advaitaa, Cai, Shuting S., Dillen, Carly A., Liu, Haiyun, Miller, Robert J., Ashbaugh, Alyssa G., Uppal, Angad S., Oyoshi, Michiko K., Malhotra, Nidhi, Hoff, Sabine, Garza, Luis A., Kong, Heidi H., Segre, Julia A., Geha, Raif S., Miller, Lloyd S.
Published in Journal of allergy and clinical immunology (01.04.2019)
Published in Journal of allergy and clinical immunology (01.04.2019)
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Journal Article
PD-1/PD-L12 COMBINATION OF REGORAFENIB AND PD-1/PD-L12 INHIBITORS FOR TREATING CANCER
KIESSLING FABIAN, HOFF SABINE, DOLESCHEL DENNIS, LEDERLE WILTRUD, ZOPF DIETER, ROESE LARS
Year of Publication 21.06.2024
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Year of Publication 21.06.2024
Patent
Abstract 4816: Anetumab ravtansine has monotherapy efficacy in mesothelin positive patient-derived NSCLC tumor models and in a syngeneic tumor model in immunocompetent mice
Sommer, Anette, Lejeune, Pascale, Hoff, Sabine, Walter, Annette O., Berndt, Sandra, Roese, Lars, Schlicker, Andreas, Wick, Michael J., Elbi, Cem, Mumberg, Dominik, Schatz, Christoph
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Selective depletion of tumor-infiltrating regulatory T cells with BAY 3375968, a novel Fc-optimized anti-CCR8 antibody
Roider, Helge G., Hoff, Sabine, Tseng, Su-Yi, Berndt, Sandra, Trautwein, Mark, Filarsky, Katharina, Gritzan, Uwe, Camps, Jordi, Nadler, Wiebke Maria, Grudzinska-Goebel, Joanna, Ellinger, Philipp, Pesch, Theresa, Soon, Chai Fen, Geyer, Marcel, Gluske, Katja, Stelte-Ludwig, Beatrix, Gorjánácz, Mátyás
Published in Clinical and experimental medicine (10.06.2024)
Published in Clinical and experimental medicine (10.06.2024)
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Journal Article
Abstract 2866: BAY 3375968: An afucosylated anti-CCR8 antibody depleting activated intratumoral regulatory T cells as a cancer immunotherapy
Roider, Helge, Tseng, Su-Yi, Hoff, Sabine, Berndt, Sandra, Filarski, Katharina, Gritzan, Uwe, Stelte-Ludwig, Beatrix, Nadler, Wiebke M., Grudzinska-Goebel, Joanna, Ellinger, Philipp, Trautwein, Mark, Gorjanacz, Matyas
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Injury, dysbiosis and filaggrin deficiency drive skin inflammation via keratinocyte IL-1α release
Archer, Nathan K., Jo, Jay-Hyun, Lee, Steven K., Kim, Dongwon, Smith, Barbara, Ortines, Roger V., Wang, Yu, Marchitto, Mark C., Ravipati, Advaitaa, Cai, Shuting S., Dillen, Carly A., Liu, Haiyun, Miller, Robert J., Ashbaugh, Alyssa G., Uppal, Angad S., Oyoshi, Michiko, Malhotra, Nidhi, Hoff, Sabine, Garza, Luis A, Kong, Heidi H., Segre, Julia A., Geha, Raif S., Miller, Lloyd S.
Published in Journal of allergy and clinical immunology (19.09.2018)
Published in Journal of allergy and clinical immunology (19.09.2018)
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Journal Article
암을 치료하기 위한 레고라페닙 및 PD-1/PD-L1 억제제의 조합
KIESSLING FABIAN, HOFF SABINE, DOLESCHEL DENNIS, LEDERLE WILTRUD, ZOPF DIETER, ROESE LARS
Year of Publication 04.02.2020
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Year of Publication 04.02.2020
Patent
항 CCR8 항체 요법: 바이오마커 및 조합 요법
OH PHAIK LYN, NADLER WIEBKE MARIA, BERTLING CHRISTIAN, STELTE LUDWIG BEATRIX, ROIDER HELGE, JONES PATRICK, GORJANACZ MATYAS, WEBER ERNST, PAWLOWSKI NIKOLAUS, ELLINGER PHILIPP, HOFF SABINE, FILARSKY KATHARINA, TRAUTWEIN MARK, TSENG SU YI, BUCHMANN PASCALE, VOTSMEIER CHRISTIAN, BERNDT SANDRA, GRITZAN UWE, VON AHSEN OLIVER, PAZ PEDRO
Year of Publication 02.03.2023
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Year of Publication 02.03.2023
Patent
치료 용도를 위한 CCR8 항체
OH PHAIK LYN, NADLER WIEBKE MARIA, BERTLING CHRISTIAN, STELTE LUDWIG BEATRIX, ROIDER HELGE, JONES PATRICK, GORJANACZ MATYAS, WEBER ERNST, PAWLOWSKI NIKOLAUS, ELLINGER PHILIPP, HOFF SABINE, FILARSKY KATHARINA, TRAUTWEIN MARK, TSENG SU YI, BUCHMANN PASCALE, VOTSMEIER CHRISTIAN, VON AHSEN OLIVER, BERNDT SANDRA, GRITZAN UWE, PAZ PEDRO
Year of Publication 28.02.2023
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Year of Publication 28.02.2023
Patent
COMBINATION OF REGORAFENIB AND NIVOLUMAB FOR TREATING CANCER
HOFF, SABINE, KIESSLING, FABIAN, RÖSE, LARS, LEDERLE, WILTRUD, DOLESCHEL, DENNIS, ZOPF, DIETER
Year of Publication 30.09.2024
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Year of Publication 30.09.2024
Patent
COMBINATION OF REGORAFENIB AND NIVOLUMAB FOR TREATING CANCER
ROESE, Lars, ZOPF, Dieter, KIESSLING, Fabian, DOLESCHEL, Dennis, LEDERLE, Wiltrud, HOFF, Sabine
Year of Publication 28.08.2024
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Year of Publication 28.08.2024
Patent
COMBINATION OF REGORAFENIB AND NIVOLUMAB FOR TREATING CANCER
Doleschel, Dennis, Lederle, Wiltrud, Zopf, Dieter, Hoff, Sabine, Kiessling, Fabian, Röse, Lars
Year of Publication 05.07.2024
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Year of Publication 05.07.2024
Patent
COMBINATION OF REGORAFENIB AND NIVOLUMAB FOR TREATING CANCER
HOFF, SABINE, KIESSLING, FABIAN, RÖSE, LARS, LEDERLE, WILTRUD, DOLESCHEL, DENNIS, ZOPF, DIETER
Year of Publication 01.07.2024
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Year of Publication 01.07.2024
Patent
COMBINATION OF REGORAFENIB AND NIVOLUMAB FOR TREATING CANCER
LEDERLE Wiltrud, DOLESCHEL Dennis, ROSE Lars, KIESSLING Fabian, ZOPF Dieter, HOFF Sabine
Year of Publication 28.06.2024
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Year of Publication 28.06.2024
Patent
COMBINATION OF REGORAFENIB AND NIVOLUMAB FOR TREATING CANCER
RÖSE, Lars, ZOPF, Dieter, KIESSLING, Fabian, DOLESCHEL, Dennis, LEDERLE, Wiltrud, HOFF, Sabine
Year of Publication 26.06.2024
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Year of Publication 26.06.2024
Patent