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Published in ENDOCRINE JOURNAL (01.01.2020)
Published in ENDOCRINE JOURNAL (01.01.2020)
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Gut microbiota confers host resistance to obesity by metabolizing dietary polyunsaturated fatty acids
Miyamoto, Junki, Igarashi, Miki, Watanabe, Keita, Karaki, Shin-ichiro, Mukouyama, Hiromi, Kishino, Shigenobu, Li, Xuan, Ichimura, Atsuhiko, Irie, Junichiro, Sugimoto, Yukihiko, Mizutani, Tetsuya, Sugawara, Tatsuya, Miki, Takashi, Ogawa, Jun, Drucker, Daniel J., Arita, Makoto, Itoh, Hiroshi, Kimura, Ikuo
Published in Nature communications (05.09.2019)
Published in Nature communications (05.09.2019)
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Low birth weight trends: possible impacts on the prevalences of hypertension and chronic kidney disease
Kanda, Takeshi, Murai-Takeda, Ayano, Kawabe, Hiroshi, Itoh, Hiroshi
Published in Hypertension research (01.09.2020)
Published in Hypertension research (01.09.2020)
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Hypertension and related diseases in the era of COVID-19: a report from the Japanese Society of Hypertension Task Force on COVID-19
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Published in Hypertension research (01.10.2020)
Published in Hypertension research (01.10.2020)
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Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians
Sato, Yuko, Atarashi, Koji, Plichta, Damian R., Arai, Yasumichi, Sasajima, Satoshi, Kearney, Sean M., Suda, Wataru, Takeshita, Kozue, Sasaki, Takahiro, Okamoto, Shoki, Skelly, Ashwin N., Okamura, Yuki, Vlamakis, Hera, Li, Youxian, Tanoue, Takeshi, Takei, Hajime, Nittono, Hiroshi, Narushima, Seiko, Irie, Junichiro, Itoh, Hiroshi, Moriya, Kyoji, Sugiura, Yuki, Suematsu, Makoto, Moritoki, Nobuko, Shibata, Shinsuke, Littman, Dan R., Fischbach, Michael A., Uwamino, Yoshifumi, Inoue, Takashi, Honda, Akira, Hattori, Masahira, Murai, Tsuyoshi, Xavier, Ramnik J., Hirose, Nobuyoshi, Honda, Kenya
Published in Nature (London) (18.11.2021)
Published in Nature (London) (18.11.2021)
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Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice
Kimura, Ikuo, Miyamoto, Junki, Ohue-Kitano, Ryuji, Watanabe, Keita, Yamada, Takahiro, Onuki, Masayoshi, Aoki, Ryo, Isobe, Yosuke, Kashihara, Daiji, Inoue, Daisuke, Inaba, Akihiko, Takamura, Yuta, Taira, Satsuki, Kumaki, Shunsuke, Watanabe, Masaki, Ito, Masato, Nakagawa, Fumiyuki, Irie, Junichiro, Kakuta, Hiroki, Shinohara, Masakazu, Iwatsuki, Ken, Tsujimoto, Gozoh, Ohno, Hiroaki, Arita, Makoto, Itoh, Hiroshi, Hase, Koji
Published in Science (American Association for the Advancement of Science) (28.02.2020)
Published in Science (American Association for the Advancement of Science) (28.02.2020)
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Long-term phase 3 study of esaxerenone as mono or combination therapy with other antihypertensive drugs in patients with essential hypertension
Rakugi, Hiromi, Ito, Sadayoshi, Itoh, Hiroshi, Okuda, Yasuyuki, Yamakawa, Satoru
Published in Hypertension research (01.12.2019)
Published in Hypertension research (01.12.2019)
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High Basolateral Glucose Increases Sodium-Glucose Cotransporter 2 and Reduces Sirtuin-1 in Renal Tubules through Glucose Transporter-2 Detection
Umino, Hiroyuki, Hasegawa, Kazuhiro, Minakuchi, Hitoshi, Muraoka, Hirokazu, Kawaguchi, Takahisa, Kanda, Takeshi, Tokuyama, Hirobumi, Wakino, Shu, Itoh, Hiroshi
Published in Scientific reports (01.05.2018)
Published in Scientific reports (01.05.2018)
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Colonic Pro-inflammatory Macrophages Cause Insulin Resistance in an Intestinal Ccl2/Ccr2-Dependent Manner
Kawano, Yoshinaga, Nakae, Jun, Watanabe, Nobuyuki, Kikuchi, Tetsuhiro, Tateya, Sanshiro, Tamori, Yoshikazu, Kaneko, Mari, Abe, Takaya, Onodera, Masafumi, Itoh, Hiroshi
Published in Cell metabolism (09.08.2016)
Published in Cell metabolism (09.08.2016)
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Barley β-glucan improves metabolic condition via short-chain fatty acids produced by gut microbial fermentation in high fat diet fed mice
Miyamoto, Junki, Watanabe, Keita, Taira, Satsuki, Kasubuchi, Mayu, Li, Xuan, Irie, Junichiro, Itoh, Hiroshi, Kimura, Ikuo
Published in PloS one (26.04.2018)
Published in PloS one (26.04.2018)
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Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes
Hasegawa, Kazuhiro, Wakino, Shu, Simic, Petra, Sakamaki, Yusuke, Minakuchi, Hitoshi, Fujimura, Keiko, Hosoya, Kozi, Komatsu, Motoaki, Kaneko, Yuka, Kanda, Takeshi, Kubota, Eiji, Tokuyama, Hirobumi, Hayashi, Koichi, Guarente, Leonard, Itoh, Hiroshi
Published in Nature medicine (01.11.2013)
Published in Nature medicine (01.11.2013)
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Efficacy and safety of dosage-escalation of low-dosage esaxerenone added to a RAS inhibitor in hypertensive patients with type 2 diabetes and albuminuria: a single-arm, open-label study
Itoh, Hiroshi, Ito, Sadayoshi, Rakugi, Hiromi, Okuda, Yasuyuki, Nishioka, Satoshi
Published in Hypertension research (01.10.2019)
Published in Hypertension research (01.10.2019)
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Chronic kidney disease reduces muscle mitochondria and exercise endurance and its exacerbation by dietary protein through inactivation of pyruvate dehydrogenase
Tamaki, Masanori, Miyashita, Kazutoshi, Wakino, Shu, Mitsuishi, Masanori, Hayashi, Koichi, Itoh, Hiroshi
Published in Kidney international (01.06.2014)
Published in Kidney international (01.06.2014)
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Comparison and commutability study between standardized liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) and chemiluminescent enzyme immunoassay for aldosterone measurement in blood
Nishikawa, Tetsuo, Satoh, Fumitoshi, Takashi, Yuichi, Yanase, Toshihiko, Itoh, Hiroshi, Kurihara, Isao, Shibata, Hirotaka, Oki, Yutaka, Naruse, Mitsuhide, Sasamoto, Hidehiko, Kuwa, Katsuhiko
Published in ENDOCRINE JOURNAL (01.01.2022)
Published in ENDOCRINE JOURNAL (01.01.2022)
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Antihypertensive effects and safety of esaxerenone in patients with moderate kidney dysfunction
Ito, Sadayoshi, Itoh, Hiroshi, Rakugi, Hiromi, Okuda, Yasuyuki, Iijima, Setsuko
Published in Hypertension research (01.05.2021)
Published in Hypertension research (01.05.2021)
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