Delivery of a BET protein degrader via a CEACAM6-targeted antibody–drug conjugate inhibits tumour growth in pancreatic cancer models
Nakazawa, Youya, Miyano, Masayuki, Tsukamoto, Shuntaro, Kogai, Hiroyuki, Yamamoto, Akihiko, Iso, Kentaro, Inoue, Satoshi, Yamane, Yoshinobu, Yabe, Yuki, Umihara, Hirotatsu, Taguchi, Junichi, Akagi, Tsuyoshi, Yamaguchi, Atsumi, Koga, Minaho, Toshimitsu, Kohta, Hirayama, Toshifumi, Mukai, Yohei, Machinaga, Akihito
Published in Nature communications (11.03.2024)
Published in Nature communications (11.03.2024)
Get full text
Journal Article
Carbon-free production of 2-deoxy-scyllo-inosose (DOI) in cyanobacterium Synechococcus elongatus PCC 7942
Watanabe, Satoru, Ozawa, Hiroaki, Kato, Hiroaki, Nimura-Matsune, Kaori, Hirayama, Toshifumi, Kudo, Fumitaka, Eguchi, Tadashi, Kakinuma, Katsumi, Yoshikawa, Hirofumi
Published in Bioscience, biotechnology, and biochemistry (01.01.2018)
Published in Bioscience, biotechnology, and biochemistry (01.01.2018)
Get full text
Journal Article
Biosynthesis of 2-deoxystreptamine-containing antibiotics in Streptoalloteichus hindustanus JCM 3268: characterization of 2-deoxy-scyllo-inosose synthase
Hirayama, Toshifumi, Tamegai, Hideyuki, Kudo, Fumitaka, Kojima, Kazumasa, Kakinuma, Katsumi, Eguchi, Tadashi
Published in Journal of antibiotics (01.06.2006)
Published in Journal of antibiotics (01.06.2006)
Get full text
Journal Article
ANTIBODY-DRUG COMPLEX
MUKAI Yohei, KATO Masaki, UMIHARA Hirotatsu, HIRAYAMA Toshifumi, MOCHIZUKI Toshiki, INOUE Satoshi, YAMAGUCHI Atsumi, MIYANO Masayuki, YAMAMOTO Yuji, ISO Kentaro, TAGUCHI Junichi, KOGAI Hiroyuki, AKAGI Tsuyoshi, YABE Yuki, SAKURADA Takato, NAKAZAWA Yuya, YAMAMOTO Akihiko, TSUKAMOTO Shuntaro
Year of Publication 29.02.2024
Get full text
Year of Publication 29.02.2024
Patent
ANTI-EphA4 ANTIBODY
ITO SHUNSUKE, YAMADA AKIO, ONO YUICHI, TAGUCHI RYOTA, HIRAYAMA TOSHIFUMI, NAKATANI AKI, IMAI TOSHIO, INOUE EIJI
Year of Publication 23.01.2020
Get full text
Year of Publication 23.01.2020
Patent
항-EPHA4 항체
ITO SHUNSUKE, YAMADA AKIO, ONO YUICHI, TAGUCHI RYOTA, HIRAYAMA TOSHIFUMI, NAKATANI AKI, IMAI TOSHIO, INOUE EIJI
Year of Publication 23.04.2018
Get full text
Year of Publication 23.04.2018
Patent
항-MYL9 항체
NAKAYAMA TOSHINORI, HAYASHIZAKI KOJI, KIMURA MOTOKO, MURAMOTO KENZO, HIRAYAMA TOSHIFUMI, KAKUTA JUNGO, SAKAMOTO YOSHIMASA, IMAI TOSHIO, GEJIMA RYU, TOKITA DAISUKE
Year of Publication 04.09.2018
Get full text
Year of Publication 04.09.2018
Patent
ANTI-EPHA4 ANTIBODY
NAKATANI, Aki, ONO, Yuichi, IMAI, Toshio, TAGUCHI, Ryota, INOUE, Eiji, YAMADA , Akio, ITO, Shunsuke, HIRAYAMA, Toshifumi
Year of Publication 16.03.2017
Get full text
Year of Publication 16.03.2017
Patent
ANTI-MYL9 ANTIBODY
HAYASHIZAKI, Koji, NAKAYAMA, Toshinori, GEJIMA, Ryu, KAKUTA, Jungo, SAKAMOTO, Yoshimasa, IMAI, Toshio, TOKITA, Daisuke, MURAMOTO, Kenzo, HIRAYAMA, Toshifumi, KIMURA, Motoko
Year of Publication 20.07.2017
Get full text
Year of Publication 20.07.2017
Patent
Structure of 2-deoxy-scyllo-inosose synthase, a key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics, in complex with a mechanism-based inhibitor and NAD
Nango, Eriko, Kumasaka, Takashi, Hirayama, Toshifumi, Tanaka, Nobuo, Eguchi, Tadashi
Published in Proteins, structure, function, and bioinformatics (01.02.2008)
Published in Proteins, structure, function, and bioinformatics (01.02.2008)
Get full text
Journal Article
Anti-Myl9 antibody
Muramoto, Kenzo, Hirayama, Toshifumi, Tokita, Daisuke, Kakuta, Jungo, Hayashizaki, Koji, Kimura, Motoko, Imai, Toshio, Nakayama, Toshinori, Gejima, Ryu, Sakamoto, Yoshimasa
Year of Publication 13.07.2023
Get full text
Year of Publication 13.07.2023
Patent
ANTIBODY-DRUG CONJUGATE
KATO, Masaki, TSUKAMOTO, Shuntaro, YABE, Yuki, YAMAGUCHI, Atsumi, SAKURADA, Takato, INOUE, Satoshi, YAMAMOTO, Yuji, MUKAI, Yohei, HIRAYAMA, Toshifumi, NAKAZAWA, Yuya, AKAGI, Tsuyoshi, MIYANO, Masayuki, ISO, Kentaro, KOGAI, Hiroyuki, TAGUCHI, Junichi, UMIHARA, Hirotatsu, MOCHIZUKI, Toshiki, YAMAMOTO, Akihiko
Year of Publication 09.05.2024
Get full text
Year of Publication 09.05.2024
Patent
ANTI-MYL9 ANTIBODY
HAYASHIZAKI, Koji, NAKAYAMA, Toshinori, GEJIMA, Ryu, KAKUTA, Jungo, SAKAMOTO, Yoshimasa, IMAI, Toshio, TOKITA, Daisuke, MURAMOTO, Kenzo, HIRAYAMA, Toshifumi, KIMURA, Motoko
Year of Publication 02.03.2022
Get full text
Year of Publication 02.03.2022
Patent
ANTI-EPHA4 ANTIBODY
NAKATANI, Aki, ONO, Yuichi, YAMADA, Akio, IMAI, Toshio, TAGUCHI, Ryota, INOUE, Eiji, ITO, Shunsuke, HIRAYAMA, Toshifumi
Year of Publication 11.11.2020
Get full text
Year of Publication 11.11.2020
Patent