Resistance to ROS1 inhibition mediated by EGFR pathway activation in non-small cell lung cancer
Davies, Kurtis D, Mahale, Sakshi, Astling, David P, Aisner, Dara L, Le, Anh T, Hinz, Trista K, Vaishnavi, Aria, Bunn, Jr, Paul A, Heasley, Lynn E, Tan, Aik-Choon, Camidge, D Ross, Varella-Garcia, Marileila, Doebele, Robert C
Published in PloS one (13.12.2013)
Published in PloS one (13.12.2013)
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Journal Article
Rapidly acquired resistance to EGFR tyrosine kinase inhibitors in NSCLC cell lines through de-repression of FGFR2 and FGFR3 expression
Ware, Kathryn E, Marshall, Marianne E, Heasley, Lydia R, Marek, Lindsay, Hinz, Trista K, Hercule, Paula, Helfrich, Barbara A, Doebele, Robert C, Heasley, Lynn E
Published in PloS one (29.11.2010)
Published in PloS one (29.11.2010)
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Journal Article
Role of epidermal growth factor receptor inhibitor-induced interferon pathway signaling in the head and neck squamous cell carcinoma therapeutic response
Korpela, Sean P, Hinz, Trista K, Oweida, Ayman, Kim, Jihye, Calhoun, Jacob, Ferris, Robert, Nemenoff, Raphael A, Karam, Sana D, Clambey, Eric T, Heasley, Lynn E
Published in Journal of translational medicine (23.01.2021)
Published in Journal of translational medicine (23.01.2021)
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Journal Article
Fibroblast Growth Factor Receptors Are Components of Autocrine Signaling Networks in Head and Neck Squamous Cell Carcinoma Cells
MARSHALL, Marianne E, HINZ, Trista K, KONO, Scott A, SINGLETON, Katherine R, BICHON, Brady, WARE, Kathryn E, MAREK, Lindsay, FREDERICK, Barbara A, RABEN, David, HEASLEY, Lynn E
Published in Clinical cancer research (01.08.2011)
Published in Clinical cancer research (01.08.2011)
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Journal Article
Therapy-induced E-cadherin downregulation alters expression of programmed death ligand-1 in lung cancer cells
Suda, Kenichi, Rozeboom, Leslie, Rivard, Christopher J, Yu, Hui, Ellison, Kim, Melnick, Mary Ann C, Hinz, Trista K, Chan, Daniel, Heasley, Lynn E, Politi, Katerina, Mitsudomi, Tetsuya, Hirsch, Fred R
Published in Lung cancer (Amsterdam, Netherlands) (01.07.2017)
Published in Lung cancer (Amsterdam, Netherlands) (01.07.2017)
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Journal Article
A Functional sgRNA-CRISPR screening method for generating murine RET and NTRK1 rearranged oncogenes
Schubert, Laura, Le, Anh T, Hinz, Trista K, Navarro, Andre C, Nelson-Taylor, Sarah K, Nemenoff, Raphael A, Heasley, Lynn E, Doebele, Robert C
Published in Biology open (15.08.2023)
Published in Biology open (15.08.2023)
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Journal Article
Nonamplified FGFR1 is a growth driver in malignant pleural mesothelioma
Marek, Lindsay A, Hinz, Trista K, von Mässenhausen, Anne, Olszewski, Kyle A, Kleczko, Emily K, Boehm, Diana, Weiser-Evans, Mary C, Nemenoff, Raphael A, Hoffmann, Hans, Warth, Arne, Gozgit, Joseph M, Perner, Sven, Heasley, Lynn E
Published in Molecular cancer research (01.10.2014)
Published in Molecular cancer research (01.10.2014)
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Journal Article
A tyrosine kinase inhibitor-induced interferon response positively associates with clinical response in EGFR-mutant lung cancer
Gurule, Natalia J., McCoach, Caroline E., Hinz, Trista K., Merrick, Daniel T., Van Bokhoven, Adriaan, Kim, Jihye, Patil, Tejas, Calhoun, Jacob, Nemenoff, Raphael A., Tan, Aik Choon, Doebele, Robert C., Heasley, Lynn E.
Published in NPJ precision oncology (17.05.2021)
Published in NPJ precision oncology (17.05.2021)
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Journal Article
Durable responses to alectinib in murine models of EML4-ALK lung cancer requires adaptive immunity
Kleczko, Emily K., Hinz, Trista K., Nguyen, Teresa T., Gurule, Natalia J., Navarro, Andre, Le, Anh T., Johnson, Amber M., Kwak, Jeff, Polhac, Diana I., Clambey, Eric T., Weiser-Evans, Mary, Merrick, Daniel T., Yang, Michael C., Patil, Tejas, Schenk, Erin L., Heasley, Lynn E., Nemenoff, Raphael A.
Published in NPJ precision oncology (04.02.2023)
Published in NPJ precision oncology (04.02.2023)
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Journal Article
FGFR1 mRNA and Protein Expression, not Gene Copy Number, Predict FGFR TKI Sensitivity across All Lung Cancer Histologies
WYNES, Murry W, HINZ, Trista K, DZIADZIUSZKO, Rafal, JASSEM, Jacek, WOJTYLAK, Szymon, SEJDA, Aleksandra, GOZGIT, Joseph M, BUNN, Paul A, CAMIDGE, D. Ross, TAN, Aik-Choon, HIRSCH, Fred R, HEASLEY, Lynn E, DEXIANG GAO, MARTINI, Michael, MAREK, Lindsay A, WARE, Kathryn E, EDWARDS, Michael G, BÖHM, Diana, PERNER, Sven, HELFRICH, Barbara A
Published in Clinical cancer research (15.06.2014)
Published in Clinical cancer research (15.06.2014)
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Journal Article
Novel EGFR-mutant mouse models of lung adenocarcinoma reveal adaptive immunity requirement for durable osimertinib response
Kleczko, Emily K., Le, Anh T., Hinz, Trista K., Nguyen, Teresa T., Navarro, Andre, Hu, Cheng-Jun, Selman, Ana M., Clambey, Eric T., Merrick, Daniel T., Lu, Sizhao, Weiser-Evans, Mary, Nemenoff, Raphael A., Heasley, Lynn E.
Published in Cancer letters (01.03.2023)
Published in Cancer letters (01.03.2023)
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Journal Article
FGFR1 Expression Levels Predict BGJ398 Sensitivity of FGFR1-Dependent Head and Neck Squamous Cell Cancers
Göke, Friederike, Franzen, Alina, Hinz, Trista K, Marek, Lindsay A, Yoon, Petros, Sharma, Rakesh, Bode, Maike, von Maessenhausen, Anne, Lankat-Buttgereit, Brigitte, Göke, Antonia, Golletz, Carsten, Kirsten, Robert, Boehm, Diana, Vogel, Wenzel, Kleczko, Emily K, Eagles, Justin R, Hirsch, Fred R, Van Bremen, Tobias, Bootz, Friedrich, Schroeck, Andreas, Kim, Jihye, Tan, Aik-Choon, Jimeno, Antonio, Heasley, Lynn E, Perner, Sven
Published in Clinical cancer research (01.10.2015)
Published in Clinical cancer research (01.10.2015)
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Journal Article
Kinome RNAi Screens Reveal Synergistic Targeting of MTOR and FGFR1 Pathways for Treatment of Lung Cancer and HNSCC
Singleton, Katherine R, Hinz, Trista K, Kleczko, Emily K, Marek, Lindsay A, Kwak, Jeff, Harp, Taylor, Kim, Jihye, Tan, Aik Choon, Heasley, Lynn E
Published in Cancer research (Chicago, Ill.) (15.10.2015)
Published in Cancer research (Chicago, Ill.) (15.10.2015)
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Journal Article
Functional RNAi Screens Define Distinct Protein Kinase Vulnerabilities in EGFR-Dependent HNSCC Cell Lines
Hinz, Trista K, Kleczko, Emily K, Singleton, Katherine R, Calhoun, Jacob, Marek, Lindsay A, Kim, Jihye, Tan, Aik Choon, Heasley, Lynn E
Published in Molecular pharmacology (01.12.2019)
Published in Molecular pharmacology (01.12.2019)
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Journal Article
Identifying kinase dependency in cancer cells by integrating high-throughput drug screening and kinase inhibition data
Ryall, Karen A, Shin, Jimin, Yoo, Minjae, Hinz, Trista K, Kim, Jihye, Kang, Jaewoo, Heasley, Lynn E, Tan, Aik Choon
Published in Bioinformatics (Oxford, England) (01.12.2015)
Published in Bioinformatics (Oxford, England) (01.12.2015)
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Journal Article
A receptor tyrosine kinase network composed of fibroblast growth factor receptors, epidermal growth factor receptor, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, and hepatocyte growth factor receptor drives growth and survival of head and neck squamous carcinoma cell lines
Singleton, Katherine R, Kim, Jihye, Hinz, Trista K, Marek, Lindsay A, Casás-Selves, Matias, Hatheway, Clark, Tan, Aik Choon, DeGregori, James, Heasley, Lynn E
Published in Molecular pharmacology (01.04.2013)
Published in Molecular pharmacology (01.04.2013)
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Journal Article
A miRNA Panel Predicts Sensitivity of FGFR Inhibitor in Lung Cancer Cell Lines
Ren, Shengxiang, Rivard, Christopher J., Yu, Hui, Genova, Carlo, Rozenboom, Leslie, Gao, Dexiang, Hinz, Trista K., Rikke, Brad A., Wynes, Murry W., Caldwell, Charles, Agustoni, Francesco, Kenichi suda, Jiang, Tao, Zhou, Caicun, Heasley, Lynn E., Hirsch, Fred R.
Published in Clinical lung cancer (01.09.2018)
Published in Clinical lung cancer (01.09.2018)
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Journal Article