Discovery of BAF312 (Siponimod), a Potent and Selective S1P Receptor Modulator
Pan, Shifeng, Gray, Nathanael S., Gao, Wenqi, Mi, Yuan, Fan, Yi, Wang, Xing, Tuntland, Tove, Che, Jianwei, Lefebvre, Sophie, Chen, Yu, Chu, Alan, Hinterding, Klaus, Gardin, Anne, End, Peter, Heining, Peter, Bruns, Christian, Cooke, Nigel G., Nuesslein-Hildesheim, Barbara
Published in ACS medicinal chemistry letters (14.03.2013)
Published in ACS medicinal chemistry letters (14.03.2013)
Get full text
Journal Article
Novel Immunomodulator FTY720 Is Phosphorylated in Rats and Humans To Form a Single Stereoisomer. Identification, Chemical Proof, and Biological Characterization of the Biologically Active Species and Its Enantiomer
Albert, Rainer, Hinterding, Klaus, Brinkmann, Volker, Guerini, Danilo, Müller-Hartwieg, Constanze, Knecht, Helmut, Simeon, Corinne, Streiff, Markus, Wagner, Trixie, Welzenbach, Karl, Zécri, Frédéric, Zollinger, Markus, Cooke, Nigel, Francotte, Eric
Published in Journal of medicinal chemistry (11.08.2005)
Published in Journal of medicinal chemistry (11.08.2005)
Get full text
Journal Article
Organic Synthesis and Biological Signal Transduction
Hinterding, Klaus, Alonso-Díaz, Daniel, Waldmann, Herbert
Published in Angewandte Chemie International Edition (03.04.1998)
Published in Angewandte Chemie International Edition (03.04.1998)
Get full text
Journal Article
A monoselective sphingosine-1-phosphate receptor-1 agonist prevents allograft rejection in a stringent rat heart transplantation model
Pan, Shifeng, Mi, Yuan, Pally, Charles, Beerli, Christian, Chen, Alice, Guerini, Danilo, Hinterding, Klaus, Nuesslein-Hildesheim, Barbara, Tuntland, Tove, Lefebvre, Sophie, Liu, Yi, Gao, Wenqi, Chu, Alan, Brinkmann, Volker, Bruns, Christian, Streiff, Markus, Cannet, Catherine, Cooke, Nigel, Gray, Nathanael
Published in Chemistry & biology (01.11.2006)
Published in Chemistry & biology (01.11.2006)
Get full text
Journal Article
S1P receptor mediated activity of FTY720 phosphate mimics
Högenauer, Klemens, Hinterding, Klaus, Nussbaumer, Peter
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
Get full text
Journal Article
Pyrazole derived from (+)-3-carene; a novel potent, selective scaffold for sphingosine-1-phosphate (S1P 1) receptor agonists
Zécri, Frédéric J., Albert, Rainer, Landrum, Gregory, Hinterding, Klaus, Cooke, Nigel G., Guerini, Danilo, Streiff, Markus, Bruns, Christian, Nuesslein-Hildesheim, Barbara
Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
Get full text
Journal Article
Synthesis of chiral analogues of FTY720 and its phosphate
Hinterding, K, Cottens, S, Albert, R, Zecri, F, Buehlmayer, PB, Spanka, C, Brinkmann, Nussbaumer, P, Ettmayer, P, Hoegenauer, K, Gray, N, Pan, SF
Published in Synthesis (Stuttgart) (01.01.2003)
Published in Synthesis (Stuttgart) (01.01.2003)
Get more information
Journal Article
Synthesis and in vitro evaluation of the farnesyltransferase inhibitor pepticinnamin E
Hinterding, K, Hagenbuch, P, Retey, J, Waldmann, H
Published in Chemistry : a European journal (01.01.1999)
Published in Chemistry : a European journal (01.01.1999)
Get full text
Journal Article
Synthesis and In Vitro Evaluation of the Farnesyltransferase Inhibitor Pepticinnamin E
Hinterding, Klaus, Hagenbuch, Patrizia, Rétey, Janos, Waldmann, Herbert
Published in Chemistry : a European journal (04.01.1999)
Published in Chemistry : a European journal (04.01.1999)
Get full text
Journal Article