A phase 1 trial of lipid-encapsulated mRNA encoding a monoclonal antibody with neutralizing activity against Chikungunya virus
August, Allison, Attarwala, Husain Z., Himansu, Sunny, Kalidindi, Shiva, Lu, Sophia, Pajon, Rolando, Han, Shu, Lecerf, Jean-Michel, Tomassini, Joanne E., Hard, Marjie, Ptaszek, Leon M., Crowe, James E., Zaks, Tal
Published in Nature medicine (01.12.2021)
Published in Nature medicine (01.12.2021)
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Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines
Hassett, Kimberly J., Benenato, Kerry E., Jacquinet, Eric, Lee, Aisha, Woods, Angela, Yuzhakov, Olga, Himansu, Sunny, Deterling, Jessica, Geilich, Benjamin M., Ketova, Tatiana, Mihai, Cosmin, Lynn, Andy, McFadyen, Iain, Moore, Melissa J., Senn, Joseph J., Stanton, Matthew G., Almarsson, Örn, Ciaramella, Giuseppe, Brito, Luis A.
Published in Molecular therapy. Nucleic acids (15.04.2019)
Published in Molecular therapy. Nucleic acids (15.04.2019)
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A multiclade env–gag VLP mRNA vaccine elicits tier-2 HIV-1-neutralizing antibodies and reduces the risk of heterologous SHIV infection in macaques
Zhang, Peng, Narayanan, Elisabeth, Liu, Qingbo, Tsybovsky, Yaroslav, Boswell, Kristin, Ding, Shilei, Hu, Zonghui, Follmann, Dean, Lin, Yin, Miao, Huiyi, Schmeisser, Hana, Rogers, Denise, Falcone, Samantha, Elbashir, Sayda M., Presnyak, Vladimir, Bahl, Kapil, Prabhakaran, Madhu, Chen, Xuejun, Sarfo, Edward K., Ambrozak, David R., Gautam, Rajeev, Martin, Malcom A., Swerczek, Joanna, Herbert, Richard, Weiss, Deborah, Misamore, Johnathan, Ciaramella, Giuseppe, Himansu, Sunny, Stewart-Jones, Guillaume, McDermott, Adrian, Koup, Richard A., Mascola, John R., Finzi, Andrés, Carfi, Andrea, Fauci, Anthony S., Lusso, Paolo
Published in Nature medicine (01.12.2021)
Published in Nature medicine (01.12.2021)
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A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection
Kose, Nurgun, Fox, Julie M, Sapparapu, Gopal, Bombardi, Robin, Tennekoon, Rashika N, de Silva, A Dharshan, Elbashir, Sayda M, Theisen, Matthew A, Humphris-Narayanan, Elisabeth, Ciaramella, Giuseppe, Himansu, Sunny, Diamond, Michael S, Crowe, Jr, James E
Published in Science immunology (17.05.2019)
Published in Science immunology (17.05.2019)
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A Lassa virus mRNA vaccine confers protection but does not require neutralizing antibody in a guinea pig model of infection
Ronk, Adam J., Lloyd, Nicole M., Zhang, Min, Atyeo, Caroline, Perrett, Hailee R., Mire, Chad E., Hastie, Kathryn M., Sanders, Rogier W., Brouwer, Philip J. M., Saphire, Erica Olmann, Ward, Andrew B., Ksiazek, Thomas G., Alvarez Moreno, Juan Carlos, Thaker, Harshwardhan M., Alter, Galit, Himansu, Sunny, Carfi, Andrea, Bukreyev, Alexander
Published in Nature communications (12.09.2023)
Published in Nature communications (12.09.2023)
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Author Correction: A phase 1 trial of lipid-encapsulated mRNA encoding a monoclonal antibody with neutralizing activity against Chikungunya virus
August, Allison, Attarwala, Husain Z., Himansu, Sunny, Kalidindi, Shiva, Lu, Sophia, Pajon, Rolando, Han, Shu, Lecerf, Jean-Michel, Tomassini, Joanne E., Hard, Marjie, Ptaszek, Leon M., Crowe, James E., Zaks, Tal
Published in Nature medicine (01.05.2022)
Published in Nature medicine (01.05.2022)
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Chimeric Fusion (F) and Attachment (G) Glycoprotein Antigen Delivery by mRNA as a Candidate Nipah Vaccine
Loomis, Rebecca J, DiPiazza, Anthony T, Falcone, Samantha, Ruckwardt, Tracy J, Morabito, Kaitlyn M, Abiona, Olubukola M, Chang, Lauren A, Caringal, Ria T, Presnyak, Vladimir, Narayanan, Elisabeth, Tsybovsky, Yaroslav, Nair, Deepika, Hutchinson, Geoffrey B, Stewart-Jones, Guillaume B E, Kueltzo, Lisa A, Himansu, Sunny, Mascola, John R, Carfi, Andrea, Graham, Barney S
Published in Frontiers in immunology (08.12.2021)
Published in Frontiers in immunology (08.12.2021)
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Rational Design and In Vivo Characterization of mRNA-Encoded Broadly Neutralizing Antibody Combinations against HIV-1
Narayanan, Elisabeth, Falcone, Samantha, Elbashir, Sayda M, Attarwala, Husain, Hassett, Kimberly, Seaman, Michael S, Carfi, Andrea, Himansu, Sunny
Published in Antibodies (Basel) (24.10.2022)
Published in Antibodies (Basel) (24.10.2022)
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Tetravalent Immunogen Assembled from Conserved Regions of HIV-1 and Delivered as mRNA Demonstrates Potent Preclinical T-Cell Immunogenicity and Breadth
Moyo, Nathifa, Wee, Edmund G, Korber, Bette, Bahl, Kapil, Falcone, Samantha, Himansu, Sunny, Wong, Adrianne L, Dey, Antu K, Feinberg, Mark, Hanke, Tomáš
Published in Vaccines (Basel) (06.07.2020)
Published in Vaccines (Basel) (06.07.2020)
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Multivalent mRNA-DTP vaccines are immunogenic and provide protection from Bordetella pertussis challenge in mice
Wolf, M. Allison, O’Hara, Joanne M., Bitzer, Graham J., Narayanan, Elisabeth, Boehm, Dylan T., Bevere, Justin R., DeJong, Megan A., Hall, Jesse M., Wong, Ting Y., Falcone, Samantha, Deal, Cailin E., Richards, Angelene, Green, Shannon, Nguyen, Brenda, King, Emily, Ogega, Clinton, Russo, Lisa, Sen-Kilic, Emel, Plante, Obadiah, Himansu, Sunny, Barbier, Mariette, Carfi, Andrea, Damron, F. Heath
Published in npj vaccines (10.06.2024)
Published in npj vaccines (10.06.2024)
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Modified mRNA Vaccines Protect against Zika Virus Infection
Richner, Justin M., Himansu, Sunny, Dowd, Kimberly A., Butler, Scott L., Salazar, Vanessa, Fox, Julie M., Julander, Justin G., Tang, William W., Shresta, Sujan, Pierson, Theodore C., Ciaramella, Giuseppe, Diamond, Michael S.
Published in Cell (09.03.2017)
Published in Cell (09.03.2017)
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SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness
Corbett, Kizzmekia S., Edwards, Darin K., Leist, Sarah R., Abiona, Olubukola M., Boyoglu-Barnum, Seyhan, Gillespie, Rebecca A., Himansu, Sunny, Schäfer, Alexandra, Ziwawo, Cynthia T., DiPiazza, Anthony T., Dinnon, Kenneth H., Elbashir, Sayda M., Shaw, Christine A., Woods, Angela, Fritch, Ethan J., Martinez, David R., Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Hutchinson, Geoffrey B., Wu, Kai, Henry, Carole, Bahl, Kapil, Garcia-Dominguez, Dario, Ma, LingZhi, Renzi, Isabella, Kong, Wing-Pui, Schmidt, Stephen D., Wang, Lingshu, Zhang, Yi, Phung, Emily, Chang, Lauren A., Loomis, Rebecca J., Altaras, Nedim Emil, Narayanan, Elisabeth, Metkar, Mihir, Presnyak, Vlad, Liu, Cuiping, Louder, Mark K., Shi, Wei, Leung, Kwanyee, Yang, Eun Sung, West, Ande, Gully, Kendra L., Stevens, Laura J., Wang, Nianshuang, Wrapp, Daniel, Doria-Rose, Nicole A., Stewart-Jones, Guillaume, Bennett, Hamilton, Alvarado, Gabriela S., Nason, Martha C., Ruckwardt, Tracy J., McLellan, Jason S., Denison, Mark R., Chappell, James D., Moore, Ian N., Morabito, Kaitlyn M., Mascola, John R., Baric, Ralph S., Carfi, Andrea, Graham, Barney S.
Published in Nature (London) (22.10.2020)
Published in Nature (London) (22.10.2020)
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Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates
Corbett, Kizzmekia S, Flynn, Barbara, Foulds, Kathryn E, Francica, Joseph R, Boyoglu-Barnum, Seyhan, Werner, Anne P, Flach, Britta, O’Connell, Sarah, Bock, Kevin W, Minai, Mahnaz, Nagata, Bianca M, Andersen, Hanne, Martinez, David R, Noe, Amy T, Douek, Naomi, Donaldson, Mitzi M, Nji, Nadesh N, Alvarado, Gabriela S, Edwards, Darin K, Flebbe, Dillon R, Lamb, Evan, Doria-Rose, Nicole A, Lin, Bob C, Louder, Mark K, O’Dell, Sijy, Schmidt, Stephen D, Phung, Emily, Chang, Lauren A, Yap, Christina, Todd, John-Paul M, Pessaint, Laurent, Van Ry, Alex, Browne, Shanai, Greenhouse, Jack, Putman-Taylor, Tammy, Strasbaugh, Amanda, Campbell, Tracey-Ann, Cook, Anthony, Dodson, Alan, Steingrebe, Katelyn, Shi, Wei, Zhang, Yi, Abiona, Olubukola M, Wang, Lingshu, Pegu, Amarendra, Yang, Eun Sung, Leung, Kwanyee, Zhou, Tongqing, Teng, I-Ting, Widge, Alicia, Gordon, Ingelise, Novik, Laura, Gillespie, Rebecca A, Loomis, Rebecca J, Moliva, Juan I, Stewart-Jones, Guillaume, Himansu, Sunny, Kong, Wing-Pui, Nason, Martha C, Morabito, Kaitlyn M, Ruckwardt, Tracy J, Ledgerwood, Julie E, Gaudinski, Martin R, Kwong, Peter D, Mascola, John R, Carfi, Andrea, Lewis, Mark G, Baric, Ralph S, McDermott, Adrian, Moore, Ian N, Sullivan, Nancy J, Roederer, Mario, Seder, Robert A, Graham, Barney S
Published in New England Journal of Medicine (15.10.2020)
Published in New England Journal of Medicine (15.10.2020)
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Modified mRNA Vaccines Protect against Zika Virus Infection
Richner, Justin M., Himansu, Sunny, Dowd, Kimberly A., Butler, Scott L., Salazar, Vanessa, Fox, Julie M., Julander, Justin G., Tang, William W., Shresta, Sujan, Pierson, Theodore C., Ciaramella, Giuseppe, Diamond, Michael S.
Published in Cell (23.03.2017)
Published in Cell (23.03.2017)
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Vaccine Mediated Protection Against Zika Virus-Induced Congenital Disease
Richner, Justin M., Jagger, Brett W., Shan, Chao, Fontes, Camila R., Dowd, Kimberly A., Cao, Bin, Himansu, Sunny, Caine, Elizabeth A., Nunes, Bruno T.D., Medeiros, Daniele B.A., Muruato, Antonio E., Foreman, Bryant M., Luo, Huanle, Wang, Tian, Barrett, Alan D., Weaver, Scott C., Vasconcelos, Pedro F.C., Rossi, Shannan L., Ciaramella, Giuseppe, Mysorekar, Indira U., Pierson, Theodore C., Shi, Pei-Yong, Diamond, Michael S.
Published in Cell (13.07.2017)
Published in Cell (13.07.2017)
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Increased neutralization potency and breadth elicited by a SARS-CoV-2 mRNA vaccine forming virus-like particles
Zhang, Peng, Falcone, Samantha, Tsybovsky, Yaroslav, Singh, Mamta, Gopan, Vinay, Miao, Huiyi, Seo, Yuna, Rogers, Denise, Renzi, Isabella, Lai, Yen-Ting, Narayanan, Elisabeth, Stewart-Jones, Guillaume, Himansu, Sunny, Carfi, Andrea, Fauci, Anthony S, Lusso, Paolo
Published in Proceedings of the National Academy of Sciences - PNAS (18.07.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (18.07.2023)
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Protective Efficacy of Nucleic Acid Vaccines Against Transmission of Zika Virus During Pregnancy in Mice
Jagger, Brett W, Dowd, Kimberly A, Chen, Rita E, Desai, Pritesh, Foreman, Bryant, Burgomaster, Katherine E, Himansu, Sunny, Kong, Wing-Pui, Graham, Barney S, Pierson, Theodore C, Diamond, Michael S
Published in The Journal of infectious diseases (08.10.2019)
Published in The Journal of infectious diseases (08.10.2019)
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Membrane-bound mRNA immunogens lower the threshold to activate HIV Env V2 apex-directed broadly neutralizing B cell precursors in humanized mice
Melzi, Eleonora, Willis, Jordan R., Ma, Krystal M., Lin, Ying-Cing, Kratochvil, Sven, Berndsen, Zachary T., Landais, Elise A., Kalyuzhniy, Oleksandr, Nair, Usha, Warner, John, Steichen, Jon M., Kalyuzhniy, Anton, Le, Amber, Pecetta, Simone, Perez, Manfredo, Kirsch, Kathrin, Weldon, Stephanie R., Falcone, Samantha, Himansu, Sunny, Carfi, Andrea, Sok, Devin, Ward, Andrew B., Schief, William R., Batista, Facundo D.
Published in Immunity (Cambridge, Mass.) (08.11.2022)
Published in Immunity (Cambridge, Mass.) (08.11.2022)
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Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors
Willis, Jordan R., Berndsen, Zachary T., Ma, Krystal M., Steichen, Jon M., Schiffner, Torben, Landais, Elise, Liguori, Alessia, Kalyuzhniy, Oleksandr, Allen, Joel D., Baboo, Sabyasachi, Omorodion, Oluwarotimi, Diedrich, Jolene K., Hu, Xiaozhen, Georgeson, Erik, Phelps, Nicole, Eskandarzadeh, Saman, Groschel, Bettina, Kubitz, Michael, Adachi, Yumiko, Mullin, Tina-Marie, Alavi, Nushin B., Falcone, Samantha, Himansu, Sunny, Carfi, Andrea, Wilson, Ian A., Yates, John R., Paulson, James C., Crispin, Max, Ward, Andrew B., Schief, William R.
Published in Immunity (Cambridge, Mass.) (08.11.2022)
Published in Immunity (Cambridge, Mass.) (08.11.2022)
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